Best TWAS P=2.66e-08 · Best GWAS P=7.38e-12 conditioned to 8.86e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Testis | TPBG | 0.11 | 0.04 | enet | 12 | 0.09 | 6.4e-05 | 2.6 | 5.6 | 2.7e-08 | 0.25 | 0.23 | 0.08 | TRUE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | DOPEY1 | 0.11 | 0.08 | enet | 45 | 0.09 | 2.9e-11 | 3.8 | -5.4 | 7.9e-08 | -0.34 | 1.00 | 0.00 | FALSE |
| 3 | YFS | Blood | RWDD2A | 0.02 | 0.01 | bslmm | 347 | 0.00 | 8.2e-03 | 4.3 | -5.4 | 7.1e-08 | -0.24 | 0.89 | 0.00 | TRUE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | DOPEY1 | 0.08 | 0.08 | blup | 47 | 0.09 | 2.3e-10 | 4.5 | -5.1 | 2.8e-07 | -0.20 | 0.01 | 0.96 | FALSE |