Best TWAS P=1.73e-09 · Best GWAS P=7.6e-09 conditioned to 0.618
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Lung Adenocarcinoma | PARP12 | 0.02 | 0.01 | blup | 68 | 0.01 | 2.4e-02 | 5.7 | -5.8 | 5.8e-09 | -0.88 | 0.01 | 0.92 | FALSE |
| 2 | The Cancer Genome Atlas | Prostate Adenocarcinoma | PARP12 | 0.06 | 0.04 | lasso | 2 | 0.04 | 1.3e-04 | 5.5 | 5.3 | 9.2e-08 | 0.93 | 0.01 | 0.98 | FALSE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | PARP12 | 0.14 | 0.11 | enet | 10 | 0.12 | 9.4e-12 | 5.8 | -6.0 | 1.7e-09 | -0.93 | 0.00 | 1.00 | TRUE |