Best TWAS P=4.88e-11 · Best GWAS P=3.74e-11 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Skin Not Sun Exposed Suprapubic | TEX10 | 0.10 | 0.09 | lasso | 4 | 0.10 | 3.1e-06 | 4.3 | 5.6 | 2.3e-08 | 0.91 | 0.02 | 0.98 | FALSE |
| 2 | GTEx | Skin Sun Exposed Lower leg | INVS | 0.19 | 0.06 | enet | 30 | 0.11 | 1.5e-09 | 5.3 | 5.3 | 9.8e-08 | 0.78 | 0.02 | 0.98 | FALSE |
| 3 | GTEx | Skin Sun Exposed Lower leg | TEX10 | 0.27 | 0.27 | lasso | 8 | 0.28 | 7.0e-23 | 6.6 | 6.6 | 4.9e-11 | 0.99 | 0.01 | 0.99 | TRUE |
| 4 | The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | INVS | 0.10 | 0.03 | blup | 107 | 0.07 | 4.0e-04 | 6.4 | 5.7 | 1.2e-08 | 0.88 | 0.01 | 0.96 | FALSE |
| 5 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | INVS | 0.09 | 0.02 | enet | 11 | 0.04 | 4.0e-05 | 5.3 | 5.2 | 2.4e-07 | 0.65 | 0.02 | 0.77 | FALSE |
| 6 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | INVS | 0.16 | 0.12 | enet | 8 | 0.08 | 2.8e-04 | 5.3 | 5.5 | 4.1e-08 | 0.77 | 0.26 | 0.62 | FALSE |