Best TWAS P=2.8e-10 · Best GWAS P=1.17e-09 conditioned to 0.00635
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Whole Blood | CTNNAL1 | 0.14 | 0.07 | lasso | 6 | 0.07 | 9.4e-07 | 3.9 | 5.3 | 1.1e-07 | 0.10 | 0.10 | 0.86 | FALSE |
| 2 | YFS | Blood | CTNNAL1 | 0.15 | 0.07 | enet | 29 | 0.08 | 2.8e-26 | 3.9 | 5.1 | 3.1e-07 | 0.23 | 0.99 | 0.01 | FALSE |
| 3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | CTNNAL1 | 0.09 | 0.00 | blup | 83 | 0.04 | 1.0e-04 | 3.9 | 6.3 | 2.8e-10 | 0.63 | 0.02 | 0.42 | TRUE |