Best TWAS P=6.83e-11 · Best GWAS P=8.76e-11 conditioned to 0.0246
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | RALGPS1 | 0.08 | 0.07 | enet | 27 | 0.09 | 3.8e-11 | 4.0 | 5.3 | 1.1e-07 | -0.77 | 0.45 | 0.55 | FALSE |
| 2 | GTEx | Esophagus Mucosa | RALGPS1 | 0.05 | 0.01 | lasso | 6 | 0.02 | 2.7e-02 | -6.5 | -6.3 | 3.3e-10 | 0.90 | 0.03 | 0.92 | FALSE |
| 3 | GTEx | Skin Sun Exposed Lower leg | RALGPS1 | 0.06 | 0.02 | lasso | 6 | 0.01 | 2.5e-02 | -6.5 | -5.9 | 2.9e-09 | 0.93 | 0.04 | 0.95 | FALSE |
| 4 | GTEx | Thyroid | RALGPS1 | 0.09 | 0.04 | enet | 12 | 0.01 | 2.7e-02 | -6.4 | 6.5 | 6.8e-11 | -0.78 | 0.02 | 0.97 | TRUE |
| 5 | METSIM | Adipose | RALGPS1 | 0.04 | 0.04 | lasso | 3 | 0.04 | 2.8e-06 | -5.8 | -6.0 | 2.3e-09 | 0.93 | 0.02 | 0.98 | FALSE |
| 6 | YFS | Blood | RALGPS1 | 0.08 | 0.13 | lasso | 18 | 0.15 | 1.1e-45 | -6.5 | -5.9 | 4.2e-09 | 0.93 | 0.02 | 0.98 | FALSE |