Best TWAS P=3.15e-09 · Best GWAS P=4.45e-08 conditioned to 0.0629
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Breast Mammary Tissue (Male) | CST7 | 0.15 | 0.0 | lasso | 4 | 0.03 | 7.0e-02 | -4.6 | -5.9 | 4.3e-09 | 0.62 | 0.06 | 0.08 | FALSE |
2 | ROSMAP | Brain Pre-frontal Cortex | ENTPD6 | 0.32 | 0.1 | bslmm | 432 | 0.12 | 1.8e-15 | 3.9 | 5.9 | 3.2e-09 | -0.70 | 0.70 | 0.24 | TRUE |