TWAS hub - ENTPD6

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1560	0.0600	5.5e-04	0.033	0.037	0.043	0.049	0.039	5.8e-05	2.1e-05	5.7e-06	1.1e-06	1.5e-05
2	GTEx	Artery Tibial	0.2350	0.0656	1.3e-10	0.115	NA	0.159	NA	0.171	2.8e-09	NA	1.9e-12	NA	2.1e-13
3	GTEx	Brain Cerebellar Hemisphere	0.2200	0.0740	6.3e-06	0.264	NA	0.169	NA	0.170	1.9e-07	NA	4.1e-05	NA	3.8e-05
4	GTEx	Brain Cerebellum	0.1480	0.0650	4.4e-04	0.230	NA	0.145	NA	0.140	2.0e-07	NA	4.6e-05	NA	6.3e-05
5	GTEx	Colon Sigmoid	0.1710	0.0720	3.0e-03	0.125	NA	0.141	NA	0.129	3.7e-05	NA	1.1e-05	NA	2.6e-05
6	GTEx	Colon Transverse	0.1040	0.0510	9.5e-03	0.093	NA	0.022	NA	0.038	3.6e-05	NA	3.0e-02	NA	6.5e-03
7	GTEx	Esophagus Mucosa	0.0910	0.0370	3.1e-05	0.038	NA	0.064	NA	0.054	1.5e-03	NA	4.2e-05	NA	1.7e-04
8	GTEx	Esophagus Muscularis	0.1610	0.0640	5.4e-04	0.030	NA	0.036	NA	0.047	6.0e-03	NA	2.8e-03	NA	7.3e-04
9	GTEx	Muscle Skeletal	0.0354	0.0192	3.9e-03	0.023	NA	0.011	NA	0.014	2.3e-03	NA	2.4e-02	NA	1.5e-02
10	GTEx	Pancreas	0.1080	0.0470	7.0e-04	0.053	NA	0.046	NA	0.039	2.9e-03	NA	5.0e-03	NA	9.4e-03
11	GTEx	Prostate	0.6210	0.0990	1.1e-04	0.027	NA	0.158	NA	0.108	7.2e-02	NA	9.1e-05	NA	1.2e-03
12	GTEx	Skin Not Sun Exposed Suprapubic	0.1160	0.0600	5.8e-03	0.087	NA	0.065	NA	0.070	1.7e-05	NA	1.8e-04	NA	1.1e-04
13	GTEx	Skin Sun Exposed Lower leg	0.1060	0.0390	3.8e-05	0.067	NA	0.040	NA	0.057	3.1e-06	NA	2.9e-04	NA	1.6e-05
14	GTEx	Stomach	0.0970	0.0540	6.6e-03	0.034	NA	0.026	NA	0.024	9.4e-03	NA	2.1e-02	NA	2.5e-02
15	ROSMAP	Brain Pre-frontal Cortex	0.3173	0.0650	2.6e-09	0.097	0.075	0.118	0.123	0.118	1.7e-12	6.3e-10	5.8e-15	1.8e-15	5.9e-15
16	TCGA	Breast Invasive Carcinoma	0.0584	0.0282	2.0e-03	0.011	0.013	0.015	NA	0.018	1.8e-03	7.5e-04	3.1e-04	NA	1.0e-04
17	TCGA	Kidney Renal Clear Cell Carcinoma	0.0851	0.0313	1.2e-07	0.029	0.063	0.063	NA	0.038	2.8e-04	1.2e-07	1.2e-07	NA	4.1e-05
18	TCGA	Kidney Renal Papillary Cell Carcinoma	0.2920	0.0760	1.3e-11	0.174	0.158	0.151	NA	0.183	3.4e-10	2.3e-09	5.5e-09	NA	1.0e-10
19	TCGA	Brain Lower Grade Glioma	0.0573	0.0259	1.9e-04	0.000	0.022	0.019	NA	0.015	3.0e-01	1.3e-03	2.7e-03	NA	7.5e-03
20	TCGA	Pheochromocytoma and Paraganglioma	0.0650	0.0390	6.8e-03	0.069	0.032	0.013	NA	0.041	1.1e-03	2.0e-02	9.7e-02	NA	9.2e-03
21	TCGA	Prostate Adenocarcinoma	0.1383	0.0576	2.9e-05	0.002	0.019	0.029	NA	0.011	1.9e-01	4.0e-03	4.5e-04	NA	2.1e-02
22	TCGA	Thyroid Carcinoma	0.1580	0.0490	3.5e-12	0.141	0.121	0.123	NA	0.130	1.2e-13	8.3e-12	5.4e-12	NA	1.2e-12

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22
Falls in the last year	8.1	11.0	18.8	-0.6	4.2	3.7	3.9	3.3	2.7	4.3	4.3	3.2	3.5	1.9	3.9	4.2	3.4	-0.9	0.3	3.7	4.1	2.4	3.6	2.6	3.7
Age at First Birth	7.6	11.1	17.6	-0.9	4.2	4.1	3.5	3.2	2.9	4.2	3.8	3.4	4.0	3.4	3.3	3.4	3.4	-1.6	-0.3	3.7	3.8	2.8	3.8	2.3	3.8
Trunk fat percentage	6.2	24.7	50.7	3.5	-5.9	-6.4	-5.9	-2.0	-1.3	-6.1	-5.7	-6.3	-7.1	-1.9	-5.7	-4.6	-2.6	6.4	2.8	-4.3	-6.0	-2.1	-6.5	-0.8	-6.3
Prostate Cancer	6.0	8.5	16.6	-0.0	2.7	3.2	2.9	2.8	2.2	3.5	3.8	3.1	3.3	2.3	4.1	3.8	2.5	-0.2	1.6	3.4	3.8	2.3	3.1	2.2	3.0
Trunk fat mass	6.0	25.6	57.6	4.4	-5.9	-6.5	-6.2	-1.7	-0.9	-6.0	-5.6	-5.8	-7.2	-1.4	-5.9	-4.7	-2.2	7.6	3.2	-3.9	-6.2	-1.6	-6.5	-0.1	-6.4
Body fat percentage	6.0	23.6	51.1	3.9	-5.7	-6.4	-5.9	-1.6	-0.8	-5.9	-5.3	-6.0	-7.1	-1.7	-5.4	-4.2	-2.2	7.0	2.8	-4.0	-5.8	-1.8	-6.4	-0.3	-6.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	5.9	12.4	29.9	1.1	3.8	5.4	4.6	1.6	1.3	4.9	3.6	5.1	4.0	1.0	2.3	2.2	2.5	-1.6	-0.3	4.2	4.0	3.1	5.5	1.3	5.4
Whole body fat mass	5.7	24.0	60.1	4.5	-5.7	-6.3	-6.1	-1.4	-0.7	-5.9	-5.3	-5.5	-7.0	-1.2	-5.6	-4.4	-2.0	7.7	3.4	-3.6	-5.9	-1.5	-6.2	0.3	-6.2
Leg fat percentage (right)	5.5	20.1	51.8	4.3	-5.0	-5.8	-5.3	-0.8	-0.2	-5.5	-4.6	-5.5	-6.7	-1.4	-4.9	-3.6	-1.4	7.2	3.2	-3.3	-5.2	-1.3	-5.8	0.6	-5.7
Leg fat mass (right)	5.2	20.3	60.2	4.7	-5.1	-5.7	-5.6	-0.8	-0.2	-5.2	-4.7	-4.9	-6.5	-1.0	-5.1	-3.9	-1.4	7.8	3.3	-2.9	-5.3	-0.9	-5.7	0.7	-5.7
Ever used hormone-replacement therapy (HRT)	5.1	6.5	14.3	1.7	-3.2	-3.1	-3.0	-1.7	-1.4	-2.8	-2.8	-2.5	-3.8	-0.9	-2.5	-2.7	-1.8	2.2	1.4	-2.9	-3.2	-1.6	-3.2	-1.9	-3.2
Leg fat percentage (left)	4.9	17.6	49.6	4.0	-4.8	-5.4	-4.9	-0.9	-0.3	-5.2	-4.3	-5.1	-6.3	-1.3	-4.4	-3.3	-1.5	7.0	3.3	-2.9	-4.6	-1.3	-5.4	0.7	-5.3
Leg fat mass (left)	4.8	18.7	59.2	4.6	-4.9	-5.5	-5.3	-0.9	-0.3	-5.0	-4.5	-4.6	-6.1	-0.8	-4.9	-3.7	-1.4	7.7	3.6	-2.7	-5.0	-0.9	-5.4	0.9	-5.4
Waist circumference	4.6	16.8	47.8	4.1	-4.9	-5.1	-5.0	-1.5	-0.8	-4.9	-4.5	-4.1	-5.7	-1.2	-4.8	-3.9	-1.8	6.9	3.0	-2.7	-4.9	-0.9	-5.1	0.4	-5.0
Arm fat mass (right)	4.6	18.8	54.6	4.3	-4.8	-5.6	-5.4	-0.8	-0.1	-5.1	-4.6	-4.8	-6.2	-1.0	-4.9	-3.7	-1.3	7.4	3.0	-2.9	-5.2	-0.8	-5.5	0.7	-5.5
Arm fat mass (left)	4.6	18.9	57.7	4.5	-4.9	-5.5	-5.4	-0.9	-0.2	-5.0	-4.6	-4.6	-6.2	-1.2	-5.0	-3.8	-1.3	7.6	3.1	-2.8	-5.2	-0.7	-5.5	0.7	-5.4
Had menopause	4.2	5.3	12.1	1.8	-2.9	-1.7	-1.7	-2.8	-2.6	-2.2	-2.8	-1.7	-3.1	-1.6	-3.2	-3.5	-2.5	1.9	1.2	-2.0	-2.8	-1.0	-1.8	-1.9	-1.8
Arm fat percentage (left)	4.2	16.9	44.7	3.8	-4.7	-5.3	-5.0	-0.7	-0.1	-4.8	-4.4	-4.9	-6.2	-1.3	-4.7	-3.4	-1.3	6.7	2.4	-3.1	-4.9	-1.1	-5.3	0.3	-5.2
Arm fat percentage (right)	4.1	16.0	41.8	3.5	-4.6	-5.4	-5.0	-0.6	0.0	-4.8	-4.1	-4.9	-6.2	-1.3	-4.3	-3.0	-1.1	6.5	2.2	-3.1	-4.7	-1.0	-5.3	0.3	-5.2
Forced expiratory volume in 1-second (FEV1), Best measure	4.1	13.0	26.7	1.3	4.1	5.2	4.5	2.1	2.0	5.0	3.9	5.2	4.2	1.5	2.2	2.3	3.2	-1.8	-0.9	4.4	3.8	4.1	5.0	0.4	5.0
LDL Cholesterol	3.9	6.2	14.3	0.2	-2.5	-3.8	-3.6	-1.0	-0.5	-2.8	-3.0	-3.2	-3.3	-0.5	-2.4	-2.3	-1.2	1.2	-1.2	-2.7	-3.5	-1.0	-3.6	-1.5	-3.6
Weight	3.9	19.2	56.1	4.5	-4.9	-5.6	-5.7	-1.1	-0.5	-5.2	-4.6	-4.3	-6.0	-0.6	-5.1	-4.1	-1.5	7.5	3.2	-2.9	-5.4	-0.7	-5.5	0.7	-5.5
Body mass index (BMI)	3.7	15.6	57.9	4.7	-4.4	-4.8	-4.8	-0.8	-0.3	-4.5	-3.9	-3.6	-5.7	-0.9	-4.5	-3.4	-1.1	7.6	3.3	-2.3	-4.5	-0.6	-4.6	1.3	-4.6
Breastfed as a baby	3.6	4.5	9.0	-1.3	2.5	2.6	3.0	1.8	1.3	2.7	2.4	1.5	2.4	1.2	2.6	2.4	1.7	-2.7	-0.5	1.9	2.7	1.5	2.4	0.2	2.6
Osteoporosis (self-reported)	3.6	4.5	8.9	1.8	-2.8	-1.3	-1.5	-2.6	-2.4	-2.0	-2.5	-1.7	-2.3	-2.1	-2.8	-3.0	-2.5	0.9	0.6	-2.6	-2.4	-1.8	-1.6	-1.8	-1.6
Pack years of smoking	3.6	5.3	9.8	0.6	-2.9	-2.9	-2.7	-1.8	-1.9	-3.1	-2.7	-3.0	-2.5	-1.6	-1.6	-2.0	-2.5	1.7	0.9	-2.4	-2.4	-1.8	-3.0	-0.6	-3.0
Forced expiratory volume in 1-second (FEV1)	3.4	11.3	25.2	0.4	4.2	4.7	4.0	2.2	2.1	4.4	3.8	5.0	4.3	1.9	2.1	2.2	3.2	-1.8	0.2	3.9	3.4	3.1	4.7	1.0	4.6
BMI	3.3	19.4	81.8	5.9	-5.2	-5.4	-5.5	-0.5	0.1	-4.8	-4.1	-4.0	-6.6	-0.7	-4.6	-3.3	-1.0	9.0	2.3	-2.0	-4.7	1.0	-5.1	1.8	-5.2
Maternal smoking around birth	3.3	4.8	9.9	1.3	-2.6	-2.6	-2.7	-1.1	-0.9	-2.6	-2.6	-2.7	-3.1	-1.5	-2.1	-2.1	-1.4	2.4	1.2	-2.4	-2.7	-1.3	-2.6	-0.7	-2.6
Chronic bronchitis/emphysema (father)	3.0	3.5	7.1	-0.4	-2.4	-2.4	-2.5	-2.0	-2.4	-2.4	-2.0	-2.4	-2.0	-1.8	-0.3	-1.2	-2.7	0.8	-0.9	-2.1	-1.4	-1.2	-2.0	-0.1	-2.2
Supplements: Fish oil (including cod liver oil)	2.9	3.7	6.9	-0.2	2.4	1.5	1.9	1.7	1.4	2.5	2.4	2.0	2.4	1.1	2.6	2.4	1.8	-0.1	1.8	2.4	2.3	1.4	1.7	2.1	1.8
Lung FVC	2.8	14.5	37.5	0.3	4.3	6.1	5.7	0.6	0.4	4.6	4.0	5.3	5.4	1.8	2.0	2.0	1.8	-2.7	0.3	3.9	4.5	1.9	6.1	1.0	6.1
Pack years adult smoking proportion	2.8	4.2	7.9	0.1	-2.5	-2.7	-2.5	-1.6	-1.8	-2.8	-2.3	-2.7	-2.1	-1.6	-1.0	-1.5	-2.4	1.6	0.5	-2.2	-2.0	-1.7	-2.8	-0.4	-2.8
Forced vital capacity (FVC)	2.7	10.3	20.7	-0.5	4.2	4.3	3.9	2.4	2.3	4.1	3.5	4.1	4.6	2.2	2.3	2.4	3.1	-1.9	0.3	3.7	3.4	2.4	4.2	1.7	4.2
Mouth/teeth dental problems: Dentures	2.7	4.5	12.2	2.5	-2.9	-2.5	-2.3	-1.0	-0.7	-2.2	-2.3	-2.7	-3.5	-1.8	-1.9	-1.8	-1.3	3.1	0.5	-1.6	-2.4	-0.5	-2.5	-0.0	-2.5
Peak expiratory flow (PEF)	2.6	6.1	11.7	1.9	2.5	3.0	2.4	2.4	2.4	3.0	2.2	3.4	2.4	2.1	1.1	1.5	2.8	0.9	2.8	3.4	2.3	2.1	2.9	2.4	2.9
Hayfever, allergic rhinitis or eczema	2.5	5.4	9.9	0.6	2.1	2.6	2.4	1.9	1.6	2.6	2.4	2.6	2.1	2.0	2.7	2.5	1.9	0.1	1.6	3.1	3.0	2.1	3.0	2.7	2.9
Medication: Lansoprazole	2.5	2.8	9.2	-1.2	1.7	0.4	0.2	1.9	1.4	1.1	2.5	1.7	0.8	1.2	2.7	2.8	1.6	0.2	0.5	1.9	2.4	1.3	1.1	3.0	0.9
Forced vital capacity (FVC), Best measure	2.5	9.1	19.4	0.7	3.6	4.4	3.9	1.6	1.5	4.1	3.2	4.2	4.1	1.5	1.9	1.9	2.5	-1.7	-0.6	3.6	3.2	3.1	4.2	0.7	4.3
Fractured/broken bones in last 5 years	2.5	3.2	5.3	0.7	1.6	1.8	1.9	1.9	1.7	1.8	2.2	1.7	0.7	-0.5	2.3	2.3	1.9	1.1	1.6	2.3	2.3	1.1	1.9	2.2	1.9
Fasting Glucose	2.4	2.9	8.5	-0.1	2.5	2.2	1.5	1.7	1.5	1.8	2.0	2.9	2.2	0.8	1.3	1.4	2.1	-0.7	0.9	2.0	1.6	0.8	1.9	-0.3	1.8
Number of live births	2.4	3.5	8.2	0.1	-2.4	-2.6	-2.5	-0.8	-0.7	-2.8	-2.2	-2.9	-2.2	-0.7	-1.0	-1.2	-1.5	1.4	0.9	-2.0	-1.9	-1.0	-2.6	-0.5	-2.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.3	2.7	7.6	0.6	1.4	2.6	1.8	0.7	0.3	2.4	1.9	2.6	1.3	0.8	1.2	1.1	1.1	-0.6	-0.5	1.9	2.0	1.4	2.8	0.3	2.6
Allergy or Eczema	2.1	5.5	10.6	0.9	1.9	2.7	2.5	1.3	0.9	2.8	2.6	3.1	2.1	1.5	2.9	2.4	1.4	0.1	1.3	3.1	3.3	2.4	3.2	2.5	3.0
Multivitamins +/- minerals	2.1	2.7	5.1	-0.3	2.1	1.7	2.2	1.4	1.2	2.3	2.0	1.8	2.0	-0.0	2.0	1.7	1.6	-0.9	-0.8	2.0	2.1	1.4	1.8	0.5	2.0
Hip circumference	2.1	9.1	41.5	3.8	-3.1	-3.8	-3.8	0.1	0.6	-3.2	-2.7	-2.7	-4.2	0.1	-3.2	-2.1	-0.2	6.4	2.5	-1.1	-3.3	0.7	-3.6	1.6	-3.7
Glaucoma (self-reported)	2.1	2.5	5.4	-1.0	1.8	2.1	2.3	1.2	0.8	2.0	1.6	1.2	1.8	-0.2	1.8	1.8	1.0	-1.0	0.3	1.7	2.3	0.6	2.0	1.1	2.1
Diabetes (father)	2.0	2.5	7.1	2.1	0.9	2.7	2.7	0.4	0.2	2.4	1.2	1.8	1.5	-0.9	0.7	0.5	0.7	1.3	-0.2	1.9	1.3	1.9	2.2	0.0	2.4
Current tobacco smoking	2.0	3.3	6.2	0.3	-1.9	-2.2	-1.6	-2.0	-2.2	-2.5	-1.9	-1.7	-1.4	-2.2	-1.2	-1.9	-2.3	1.7	0.5	-1.7	-2.0	-1.6	-2.3	-0.3	-2.2
Arm predicted mass (left)	2.0	10.2	40.2	4.2	-3.6	-3.7	-4.3	-1.0	-0.6	-3.6	-3.0	-1.9	-4.0	-0.2	-3.7	-3.2	-1.1	6.3	3.0	-1.5	-3.8	0.0	-3.5	1.3	-3.7
Breast Cancer	1.9	4.5	9.2	1.8	-2.2	-3.0	-2.5	-0.6	-0.3	-2.8	-2.3	-2.0	-2.6	0.3	-1.7	-1.9	-0.8	2.2	2.3	-2.5	-2.7	-1.7	-3.0	-0.3	-2.9
Smoking Status	1.9	4.5	17.8	0.7	-1.0	-3.3	-2.7	0.4	0.3	-2.6	-0.8	-2.2	-1.8	1.1	-0.1	-0.1	-0.2	4.2	2.8	-1.1	-1.7	-1.3	-3.2	3.2	-3.2
Eye problems/disorders: Diabetes related eye disease	1.9	2.1	4.9	0.3	-1.6	-1.4	-1.0	-1.4	-1.4	-1.5	-1.7	-1.3	-1.3	-0.2	-1.3	-1.8	-1.4	0.0	0.5	-2.2	-1.8	-2.1	-1.7	-1.9	-1.5
Leg fat-free mass (left)	1.9	10.1	34.6	3.5	-3.3	-4.0	-4.5	-0.6	-0.2	-3.5	-3.4	-2.4	-3.7	0.2	-3.8	-3.2	-0.9	5.9	3.0	-1.6	-4.0	-0.3	-3.9	1.1	-4.0
Sitting height	1.9	13.4	34.5	0.1	-3.5	-5.6	-5.9	-1.7	-1.3	-4.4	-4.2	-3.6	-3.8	-0.1	-3.7	-3.9	-2.0	2.5	-0.5	-3.8	-5.3	-1.6	-5.6	-0.8	-5.7
Leg predicted mass (left)	1.9	9.9	34.1	3.5	-3.2	-4.0	-4.4	-0.5	-0.1	-3.4	-3.3	-2.4	-3.7	0.2	-3.7	-3.1	-0.8	5.8	2.9	-1.6	-4.0	-0.3	-3.9	1.1	-4.0
Vitamin and mineral supplements	1.8	2.5	4.8	-0.6	-1.8	-1.7	-1.8	-1.4	-1.3	-2.2	-1.9	-1.9	-1.4	-0.3	-1.3	-1.4	-1.7	0.2	0.4	-2.1	-1.9	-2.0	-1.9	-0.9	-1.9
Hearing difficulty/problems with background noise	1.8	2.9	8.5	-2.0	1.9	1.6	2.2	1.7	1.3	1.7	1.5	0.5	2.6	-0.5	2.9	2.6	0.9	-1.7	0.3	1.2	2.3	-0.5	1.6	1.3	1.7
Emphysema/chronic bronchitis	1.8	2.0	5.9	0.5	-1.8	-1.5	-1.2	-0.9	-1.2	-1.6	-1.4	-1.3	-1.4	-1.2	0.0	-0.7	-1.7	2.4	2.0	-1.1	-1.0	-1.6	-1.7	1.2	-1.6
Breast cancer (self-reported)	1.8	2.1	4.6	-0.6	1.5	2.0	1.9	0.3	-0.2	2.1	1.7	1.9	1.9	-1.4	1.5	1.3	0.4	-1.5	-0.1	1.4	1.8	1.1	1.8	0.0	1.8
Basal metabolic rate	1.8	9.7	40.6	4.1	-3.2	-3.7	-4.2	-0.4	-0.1	-3.3	-3.0	-2.1	-3.8	0.2	-3.6	-3.0	-0.7	6.4	3.1	-1.2	-3.7	0.3	-3.6	1.4	-3.7
Arm fat-free mass (left)	1.8	9.4	37.8	4.2	-3.4	-3.6	-4.1	-0.7	-0.3	-3.3	-3.0	-2.0	-3.9	-0.4	-3.6	-3.0	-0.9	6.1	2.7	-1.3	-3.6	0.3	-3.4	1.3	-3.5
Bipolar Disorder or Schizophrenia	1.7	4.2	7.9	1.3	-2.7	-1.3	-1.4	-2.7	-2.8	-2.1	-2.3	-1.3	-1.9	-2.1	-2.3	-2.8	-2.6	1.1	0.7	-2.2	-2.4	-1.6	-1.6	-2.3	-1.6
Arm fat-free mass (right)	1.7	8.6	35.3	4.3	-3.3	-3.0	-3.7	-1.2	-1.0	-3.0	-3.0	-1.4	-3.4	-0.4	-3.6	-3.4	-1.4	5.9	3.1	-1.0	-3.5	0.0	-2.9	1.1	-3.1
Mean time to correctly identify matches	1.7	3.3	8.0	-1.3	-1.7	-1.7	-1.1	-1.0	-0.8	-1.6	-1.8	-2.6	-1.8	-1.4	-1.6	-1.3	-1.2	-1.9	-2.4	-2.8	-1.9	-1.7	-1.9	-2.7	-1.8
Arm predicted mass (right)	1.7	8.5	35.1	4.1	-3.3	-3.1	-3.7	-0.9	-0.6	-2.9	-3.0	-1.7	-3.4	-0.3	-3.5	-3.1	-1.1	5.9	3.1	-1.1	-3.5	-0.0	-3.1	1.2	-3.2
Chest pain or discomfort	1.7	2.5	7.1	0.9	-2.3	-2.0	-1.9	0.2	0.3	-1.3	-1.9	-2.5	-2.7	-2.1	-1.2	-0.6	-0.6	2.1	0.9	-1.1	-1.5	-0.4	-1.9	0.3	-2.0
Commuting to job workplace: Walk	1.7	1.8	4.5	-0.5	1.4	2.0	2.1	1.0	1.0	1.6	1.4	1.8	1.5	0.0	1.2	1.2	1.1	-0.6	-0.2	1.6	1.7	0.5	1.9	0.0	2.0
Smoking status: Current	1.7	2.6	5.2	0.1	-1.6	-2.0	-1.5	-1.7	-1.9	-2.3	-1.7	-1.7	-1.2	-2.0	-1.0	-1.6	-2.0	1.5	0.2	-1.5	-1.8	-1.1	-2.2	-0.4	-2.1
Medication: Atorvastatin	1.7	2.1	4.2	1.3	-2.0	-0.6	-1.3	-2.0	-2.0	-1.3	-1.6	-0.4	-1.4	-1.9	-1.8	-1.9	-2.1	1.3	-0.4	-1.2	-1.2	-1.4	-0.6	-0.9	-0.7
Bipolar Disorder (2018)	1.6	2.5	4.9	-0.4	-1.9	-1.4	-1.6	-1.9	-2.0	-1.5	-2.0	-1.2	-1.1	-2.2	-1.3	-1.8	-2.1	0.4	0.5	-1.6	-1.8	-1.6	-1.6	-1.2	-1.7
Alzheimer’s Disease (in father)	1.6	1.8	4.0	1.8	0.6	1.6	1.3	1.0	0.8	1.6	1.2	1.7	0.6	-0.3	0.6	1.1	1.1	1.3	0.6	1.9	1.3	2.0	1.7	1.4	1.6
Body Mass Index (BMI) (2010)	1.6	2.2	9.3	2.6	-0.9	-1.7	-1.6	0.5	0.8	-1.4	-1.3	-1.1	-1.7	0.2	-1.9	-1.3	0.4	3.0	1.6	-0.2	-1.8	0.6	-1.7	0.8	-1.6
Systolic blood pressure, automated reading	1.6	4.8	16.9	4.1	-2.6	-1.4	-1.7	-0.8	0.1	-1.6	-2.4	-1.1	-3.2	-2.2	-3.6	-2.8	-0.2	4.0	-0.5	-0.7	-2.8	1.7	-1.2	-1.0	-1.3
Tinnitus: Yes, but not now, but have in the past	1.6	1.7	4.7	0.6	-1.8	-0.9	-0.5	-1.3	-1.3	-1.5	-1.7	-1.9	-2.0	-2.2	-1.3	-1.4	-1.6	0.4	-0.5	-1.5	-1.1	-0.2	-1.0	-1.2	-0.9
Health satisfaction	1.6	2.1	6.3	1.2	1.2	1.5	1.4	1.0	0.7	0.9	1.7	1.8	0.9	1.0	0.8	1.1	1.2	2.0	2.3	2.0	1.6	0.6	1.3	2.5	1.4
Neuroticism (2016)	1.5	2.2	4.3	-0.3	1.8	1.9	2.1	1.0	0.4	1.8	1.9	2.0	1.7	0.6	1.9	1.5	1.1	0.2	0.1	2.0	1.9	0.4	1.6	1.3	1.8
Rheumatoid Arthritis	1.5	2.0	5.5	1.0	-1.8	-1.6	-2.3	-1.1	-1.3	-1.9	-1.7	-1.6	-1.5	-0.7	-1.1	-1.6	-1.5	0.8	-0.8	-1.5	-1.8	0.1	-1.4	-0.4	-1.7
Diabetes (mother)	1.5	2.0	7.7	2.8	0.6	0.3	0.4	1.8	2.5	1.1	0.5	0.6	-0.5	-0.4	-0.6	0.3	2.3	2.6	0.3	1.6	0.0	2.5	0.5	1.1	0.6
Wheeze or whistling in the chest in last year	1.5	2.7	7.3	0.3	-1.4	-2.7	-2.3	0.8	0.7	-1.7	-1.4	-2.7	-2.6	-0.3	-0.5	-0.1	0.0	2.3	0.7	-0.7	-1.5	0.4	-2.7	0.9	-2.6
Number of children fathered	1.5	1.7	9.7	2.7	-1.5	-1.3	-1.6	0.2	0.6	-0.8	-0.9	-0.3	-1.6	-0.5	-0.7	-0.7	0.1	3.1	-0.3	0.2	-1.1	1.6	-1.1	1.0	-1.2
Mouth/teeth dental problems: Mouth ulcers	1.5	2.4	6.5	-1.7	2.0	1.6	2.1	1.9	1.6	1.8	1.2	0.5	2.5	0.3	1.9	1.8	1.5	-1.3	-0.8	0.9	1.6	-1.0	1.3	1.1	1.5
Supplements: Zinc	1.4	1.5	4.5	-0.9	2.1	1.0	1.3	1.3	1.4	1.3	1.5	1.0	1.4	0.6	0.8	1.2	1.6	-0.6	0.8	1.2	1.4	-0.5	1.1	1.3	1.2
Severe depression (siblings)	1.4	1.6	3.3	0.5	-1.3	-1.6	-1.4	-0.4	-0.3	-1.5	-1.7	-1.7	-1.1	-0.5	-1.3	-1.2	-0.7	1.8	-0.3	-1.3	-1.7	-1.0	-1.7	-0.2	-1.7
Qualifications: None of the above	1.4	3.0	7.8	1.4	-2.4	-1.5	-1.1	-1.6	-1.3	-2.4	-2.0	-1.8	-2.1	-2.8	-1.3	-1.7	-1.9	1.6	0.6	-2.0	-1.8	-1.5	-1.6	-0.9	-1.5
Qualifications: O levels/GCSEs or equivalent	1.4	2.3	5.3	-1.0	1.9	1.9	1.3	1.3	1.4	2.1	1.2	1.8	2.1	1.8	0.5	0.7	1.6	-2.3	-0.3	1.1	1.1	0.6	1.9	-0.9	1.8
Comparative body size at age 10	1.4	3.7	13.2	-0.9	-1.6	-3.2	-3.6	-0.0	0.1	-2.4	-1.6	-2.8	-2.2	0.1	-0.4	-0.7	-0.7	1.4	-0.1	-2.1	-2.2	-1.2	-3.0	1.0	-3.3
Angina (self-reported)	1.4	1.9	4.5	1.1	-2.1	-1.6	-1.6	-0.2	-0.1	-1.7	-1.6	-1.9	-2.0	-2.1	-1.1	-0.8	-0.8	1.5	-0.0	-1.5	-1.4	-0.4	-1.3	0.5	-1.4
Leg fat-free mass (right)	1.4	7.3	28.4	3.1	-2.7	-3.4	-3.8	-0.5	-0.2	-2.8	-2.7	-1.7	-3.0	0.4	-3.0	-2.7	-0.8	5.3	2.8	-1.1	-3.3	-0.1	-3.2	1.2	-3.4
Mother’s age at death	1.4	1.8	9.1	-1.1	-0.8	-0.5	-0.4	-1.2	-1.1	-0.6	-1.5	-0.9	0.3	0.7	-1.2	-1.5	-1.2	-1.9	-0.4	-1.8	-1.5	-2.2	-1.1	-3.0	-0.8
Worry (Nagel 2018)	1.3	2.8	22.0	-2.9	-0.1	0.2	-0.2	-1.1	-1.1	-0.2	-0.8	-0.7	0.7	-0.4	-0.3	-0.6	-1.2	-4.7	-3.5	-1.7	-0.4	-1.7	0.1	-2.7	-0.0
Crohns Disease (2017)	1.3	2.9	12.0	2.3	-2.0	-1.7	-1.6	-1.2	-1.0	-1.5	-2.0	-1.5	-1.8	-0.9	-1.6	-1.8	-1.4	3.5	1.4	-0.9	-2.0	-0.6	-2.0	0.1	-1.9
Reaction Time	1.3	2.4	7.7	-1.5	-1.1	-1.4	-0.7	-0.3	-0.1	-1.2	-1.1	-2.2	-1.3	-0.4	-1.0	-0.7	-0.5	-2.3	-2.5	-2.5	-1.6	-1.3	-1.8	-2.8	-1.6
Heel T-Score	1.3	10.6	20.2	-3.2	4.1	2.1	2.1	4.4	4.0	4.1	3.7	1.9	3.3	2.0	4.1	4.5	4.1	-2.8	-3.0	2.9	3.3	2.7	2.2	2.3	2.2
Waist Hip Ratio (WHR)	1.3	5.9	10.1	1.3	-3.2	-2.3	-2.0	-2.1	-1.8	-3.0	-3.0	-2.2	-3.2	-2.2	-2.7	-3.0	-2.2	2.0	1.4	-2.2	-3.0	-1.4	-2.7	-2.4	-2.5
Hearing difficulty/problems: Yes	1.3	2.0	5.9	-0.8	1.3	1.5	2.1	1.1	0.6	1.5	1.6	0.6	1.5	0.3	2.4	2.3	0.5	-0.3	0.7	1.5	2.2	0.5	1.5	1.5	1.6
Alcohol usually taken with meals	1.3	2.0	4.6	-0.9	1.8	2.0	2.0	1.2	1.1	2.1	1.2	1.2	1.4	1.6	-0.1	0.8	1.6	-1.9	-0.6	1.6	1.2	1.2	1.5	-0.7	1.7
Nervous feelings	1.3	2.4	17.0	-2.9	0.5	0.9	0.5	-0.9	-1.0	0.5	-0.5	0.1	1.6	-0.3	-0.3	-0.6	-0.8	-4.1	-2.8	-1.1	-0.0	-1.7	0.7	-2.7	0.7
Loud music exposure frequency	1.3	1.4	9.2	3.0	-1.2	0.9	1.0	-1.6	-1.8	0.1	0.0	0.9	-0.6	-1.3	-0.4	-0.8	-1.3	1.7	0.3	0.1	0.0	1.1	0.7	-1.2	0.7
Pulse rate, automated reading	1.3	4.1	11.6	2.3	-1.8	-1.0	-2.0	-3.4	-3.0	-1.8	-1.2	1.4	-1.9	-1.0	-3.1	-3.4	-2.2	2.4	1.4	-1.0	-2.3	-0.6	-0.6	-1.5	-1.0
Smoking status: Previous	1.3	2.0	10.0	0.6	0.6	-0.6	-0.6	1.9	1.8	0.1	0.9	-0.2	-0.5	2.5	0.9	1.4	1.6	2.3	2.6	0.6	0.4	0.3	-0.3	3.2	-0.4
Mineral and other dietary supplements	1.3	1.7	4.9	0.6	-1.4	-0.7	-1.0	-1.2	-1.1	-1.7	-1.5	-1.0	-1.6	-0.2	-2.2	-1.9	-1.0	-0.2	-1.5	-1.5	-1.7	-0.5	-0.9	-2.2	-0.9
Leg predicted mass (right)	1.3	6.9	27.7	3.1	-2.6	-3.3	-3.8	-0.4	-0.2	-2.7	-2.6	-1.6	-2.9	0.4	-2.9	-2.6	-0.7	5.3	2.7	-1.1	-3.2	-0.0	-3.1	1.2	-3.3
Verbal and Numeric Reasoning (VNR)	1.2	3.0	7.2	0.9	-1.7	-2.2	-2.7	-0.6	-0.6	-2.2	-2.0	-1.5	-2.3	0.9	-2.4	-2.1	-0.8	1.7	0.6	-1.4	-2.2	-1.0	-2.2	-0.4	-2.3
Ulcerative Colitis	1.2	1.7	4.4	-0.5	1.4	1.6	1.9	0.1	-0.3	1.7	1.4	1.6	2.1	0.1	1.7	1.2	0.2	-0.9	0.0	1.5	1.8	0.7	1.7	0.6	1.8
Blood Platelet Count	1.2	14.3	33.8	-2.8	-3.2	-4.0	-4.4	-5.8	-5.6	-5.8	-3.4	-3.4	-1.8	-0.8	-2.8	-3.7	-5.8	-1.1	2.2	-4.2	-3.0	-4.6	-3.3	-1.9	-3.7
Angina	1.2	1.6	4.1	1.5	-2.0	-1.3	-1.3	-0.3	-0.2	-1.4	-1.4	-1.8	-1.9	-2.0	-1.0	-0.7	-0.8	1.6	0.2	-1.3	-1.2	-0.2	-1.2	0.4	-1.2
Heel bone mineral density (BMD) T-score, automated (left)	1.2	2.7	7.6	-0.2	1.8	1.2	1.1	2.2	2.0	2.1	1.3	1.1	1.7	0.9	1.5	1.9	1.8	0.7	0.4	2.8	1.8	2.1	1.3	2.4	1.3
Medication: Levothyroxine sodium	1.2	2.1	6.9	1.9	1.1	1.6	1.2	1.8	1.9	1.7	1.0	1.3	0.8	2.6	0.0	0.5	2.1	1.2	0.8	1.9	0.9	1.6	1.2	0.9	1.3
Alcohol intake versus 10 years previously	1.2	1.8	4.9	1.0	-1.7	-0.4	-0.6	-2.1	-1.8	-0.6	-1.6	-0.3	-1.3	-1.8	-1.5	-2.2	-1.8	0.7	-0.2	-1.5	-1.5	-0.9	-0.3	-2.0	-0.4
Pulse wave reflection index	1.2	1.5	4.4	-0.2	1.3	0.7	0.9	2.0	1.6	1.0	1.5	0.6	0.5	0.8	1.9	2.1	1.8	0.6	0.2	1.1	1.3	0.4	0.6	2.0	0.7
Headache pain in last month	1.2	2.1	4.1	-0.0	1.8	1.9	2.0	1.0	1.2	2.0	1.5	2.0	1.9	-0.0	1.2	1.2	1.4	-0.3	0.7	1.7	1.5	-0.2	1.9	0.3	2.0
Age at first live birth	1.2	2.2	8.0	-1.3	1.5	2.3	1.5	0.3	0.4	2.0	0.6	1.4	2.2	0.6	-0.2	0.2	0.7	-2.8	-1.3	1.5	1.2	1.0	2.2	-0.4	2.1
Medication: Omeprazole	1.2	1.4	4.6	1.0	-1.2	-0.6	-0.3	-0.6	-0.8	-1.4	-1.6	-1.9	-0.8	-0.6	-1.0	-1.0	-1.1	1.7	1.6	-1.4	-0.9	-2.2	-0.8	0.6	-0.7
Heart disease (mother)	1.2	1.5	4.0	0.3	-1.4	-1.0	-1.1	-1.1	-1.1	-1.3	-1.4	-1.5	-1.3	-2.0	-1.3	-1.2	-1.2	0.0	-1.8	-1.6	-1.3	-0.6	-0.9	-0.7	-1.0
Whole body fat-free mass	1.2	7.0	32.4	3.8	-2.6	-3.0	-3.6	-0.2	0.0	-2.5	-2.5	-1.3	-2.9	0.5	-3.1	-2.6	-0.4	5.7	2.9	-0.7	-3.1	0.5	-2.8	1.6	-3.0
Mood swings	1.2	2.1	7.2	-0.5	-1.9	-1.6	-1.3	-0.9	-0.9	-1.4	-1.6	-1.8	-1.7	-0.5	-0.5	-0.7	-1.4	-0.5	0.9	-2.3	-1.3	-2.7	-1.8	-1.0	-1.7
Medication: Gliclazide	1.2	1.4	5.9	1.9	0.1	0.9	0.5	-0.0	-0.2	0.3	1.2	1.9	-0.2	1.4	0.5	0.3	0.3	2.4	2.1	1.2	1.2	0.7	1.2	1.6	1.1
Whole body water mass	1.2	7.1	32.6	3.9	-2.6	-3.0	-3.6	-0.4	-0.1	-2.6	-2.5	-1.3	-3.0	0.4	-3.1	-2.7	-0.5	5.7	2.8	-0.7	-3.2	0.5	-2.8	1.5	-3.0
Ovarian Cancer	1.1	1.5	4.0	-0.1	-2.0	-0.9	-0.8	-1.3	-1.3	-1.4	-1.3	-1.6	-1.4	-0.9	-1.0	-1.0	-1.6	-0.1	-1.0	-2.0	-1.0	-1.0	-1.0	-1.5	-1.0
Mean Putamen Volume	1.1	1.2	4.1	-0.5	1.3	1.7	1.6	-0.2	-0.5	1.4	1.3	2.0	1.5	-0.0	0.7	0.5	0.2	-1.0	0.7	1.0	1.2	0.3	1.5	-0.2	1.6
Ever unenthusiastic/disinterested for a whole week	1.1	1.4	3.2	-1.4	1.2	1.1	1.3	0.9	0.4	0.8	1.7	1.0	1.2	0.1	1.8	1.5	0.6	-0.4	0.8	0.1	1.6	-1.7	0.9	1.7	1.0
Fluid intelligence score	1.1	2.3	5.0	1.0	-1.7	-1.8	-2.2	-0.9	-0.8	-2.0	-1.7	-1.2	-2.2	0.5	-2.0	-1.9	-0.9	1.7	1.1	-1.2	-1.6	-1.1	-1.5	-0.0	-1.6
Mouth/teeth dental problems: Loose teeth	1.1	1.3	8.3	-0.4	0.1	-1.3	-1.4	1.2	1.1	-1.0	0.2	-0.1	-0.1	2.1	0.6	0.8	0.8	1.8	1.1	-0.0	-0.0	-0.3	-0.8	2.9	-1.0
Suffer from ‘nerves’	1.1	1.8	4.6	-0.6	-1.3	-0.7	-1.0	-1.3	-1.2	-1.5	-1.3	-1.1	-1.1	-0.4	-1.2	-1.4	-1.2	-1.6	-2.1	-2.0	-1.2	-1.9	-0.7	-1.9	-0.8
Loneliness, isolation	1.1	1.5	5.2	-0.8	0.4	-1.5	-1.2	2.3	2.0	-0.2	0.6	-1.1	-0.6	1.5	1.3	1.6	1.5	0.7	-0.1	0.2	0.1	0.5	-1.4	2.1	-1.4
Deep venous thrombosis (DVT) (self-reported)	1.1	1.4	3.6	-0.2	-0.9	-0.9	-1.1	-1.8	-1.9	-1.7	-1.0	0.1	-0.3	-0.7	-1.3	-1.7	-1.6	0.6	0.8	-1.0	-1.3	-1.8	-0.8	-0.4	-0.9
Schizophrenia (2018)	1.0	2.2	6.0	1.9	-1.9	-0.6	-0.6	-1.9	-1.9	-1.6	-1.4	-0.6	-1.6	-0.8	-1.9	-2.2	-1.6	1.0	0.0	-1.6	-1.6	-0.7	-0.7	-2.4	-0.7
Blood Red Count	1.0	9.7	47.6	3.2	-1.9	1.2	0.6	-5.2	-4.3	-1.0	-2.4	1.4	-0.7	-2.5	-5.7	-5.8	-3.1	-1.1	-0.9	-1.7	-2.8	-0.4	0.8	-6.9	0.9
Hand grip strength (left)	1.0	2.7	11.9	1.3	1.3	0.9	0.3	2.0	2.0	1.4	0.9	1.3	1.3	2.3	0.1	0.9	2.0	1.9	-0.3	3.0	0.9	3.5	1.0	1.7	0.9
Bilateral oophorectomy (both ovaries removed)	1.0	1.1	4.8	0.6	-1.3	-0.2	0.1	-2.0	-2.2	-0.7	-0.9	-0.6	-0.5	-1.8	-0.3	-0.7	-2.1	-0.1	0.1	-0.7	-0.3	-0.4	-0.3	-1.8	-0.3
Number of incorrect matches in round	1.0	1.7	4.8	1.8	-2.2	-0.5	-0.7	-1.8	-1.9	-0.5	-1.4	-1.0	-1.6	-1.6	-1.0	-1.3	-2.0	1.5	-0.2	-1.0	-1.0	-0.3	-0.7	-0.4	-0.7
Heel bone mineral density (BMD) T-score, automated (right)	1.0	2.4	6.5	0.3	1.5	1.3	1.2	2.0	1.7	2.2	1.2	1.3	1.5	0.5	1.4	1.7	1.7	0.7	0.2	2.6	1.6	2.4	1.3	1.9	1.4
Illnesses of siblings	1.0	1.4	4.7	-2.1	1.2	0.7	0.8	1.0	0.9	1.2	1.4	0.9	1.0	1.2	1.6	1.7	0.9	-2.2	-1.0	0.6	1.2	0.4	0.5	-0.6	0.5
Worrier / anxious feelings	1.0	1.9	16.5	-2.5	0.7	1.1	1.1	-0.3	-0.5	0.7	-0.1	-0.3	1.4	0.5	-0.2	0.1	-0.4	-4.1	-1.8	-0.7	0.4	-1.6	0.6	-2.4	0.7
Lung cancer (father)	1.0	1.2	9.2	0.1	0.4	1.0	1.0	0.8	0.6	0.9	0.7	0.9	0.3	-0.0	1.0	1.2	0.5	1.4	1.4	1.1	1.3	-0.6	0.9	3.0	0.9
Trunk predicted mass	1.0	5.5	29.5	3.8	-2.1	-2.5	-3.1	0.0	0.2	-2.1	-1.9	-0.8	-2.5	0.7	-2.6	-2.2	-0.1	5.4	2.7	-0.3	-2.7	1.0	-2.3	1.8	-2.4
Exposure to tobacco smoke at home	1.0	1.1	3.0	-0.2	-1.3	-1.7	-1.6	-1.0	-1.2	-1.5	-0.7	-1.0	-1.4	-0.8	-0.1	-0.3	-1.4	0.9	0.3	-0.8	-0.7	-0.5	-1.5	-0.1	-1.6
Birth weight of first child	1.0	1.8	5.2	0.4	-1.8	-1.6	-1.2	-0.2	-0.2	-1.6	-1.4	-2.1	-2.1	-1.4	-0.6	-0.6	-0.6	-0.0	-0.9	-2.3	-1.6	-0.6	-1.8	-1.1	-1.6
Medication for cholesterol, blood pressure or diabetes	1.0	1.6	9.7	-3.1	0.1	-1.0	-0.8	0.3	0.3	-0.6	-0.6	-1.4	0.6	1.1	0.4	0.2	-0.1	-3.1	-0.8	-1.4	-0.6	-1.3	-1.3	-1.7	-1.2
Chronic bronchitis/emphysema (mother)	1.0	1.1	2.5	-0.1	-1.4	-1.2	-1.2	-1.0	-1.2	-1.2	-1.3	-1.5	-0.5	-0.1	-0.3	-0.7	-1.5	0.4	0.2	-1.2	-1.0	-1.0	-1.6	-0.4	-1.6
Seen a psychiatrist for nerves, anxiety, tension or depression	1.0	1.3	6.7	-0.0	-0.8	0.6	0.2	-2.3	-2.6	-0.3	-0.1	0.6	0.1	-1.2	-0.3	-0.9	-2.0	-1.6	-0.1	-0.9	0.3	-1.4	0.7	-1.5	0.5
Medication: Allopurinol	1.0	1.3	5.4	1.4	-1.6	-0.9	-1.0	-0.6	-0.3	-1.5	-0.9	-0.7	-1.9	0.2	-0.8	-0.6	-0.7	2.3	1.7	-0.8	-0.6	-0.8	-0.6	1.3	-0.7
Back pain experienced in last month	1.0	1.5	9.7	2.6	-1.2	-0.7	-0.6	0.0	0.1	-0.5	-0.6	-0.5	-1.7	-1.7	-0.6	-0.5	-0.0	3.1	1.8	-0.3	-0.9	0.0	-0.7	0.7	-0.7
Osteoarthritis (self-reported)	1.0	1.2	3.1	1.5	-0.5	1.6	1.1	-0.9	-1.1	1.0	0.2	1.3	0.4	-1.7	0.5	0.3	-0.9	1.1	0.4	1.5	1.2	1.1	1.8	0.6	1.6
Number of self-reported non-cancer illnesses	1.0	1.8	12.8	2.8	-1.5	-0.0	0.0	0.3	0.2	-0.7	-1.1	-1.2	-1.6	-2.2	-1.1	-0.5	-0.3	3.6	1.6	0.3	-0.3	-0.1	-0.2	1.0	-0.1
Eye problems/disorders: Glaucoma	1.0	1.1	2.5	-1.0	1.4	1.1	0.9	0.9	0.6	1.2	1.2	1.0	1.6	0.9	1.4	1.3	0.8	-1.1	-0.3	1.1	1.4	0.9	1.1	0.6	1.1
Unable to work because of sickness or disability	1.0	1.3	3.3	1.6	0.4	1.8	1.7	-0.8	-1.0	1.1	-0.1	1.0	1.0	-1.2	-0.4	-0.6	-0.6	0.6	1.5	1.5	0.9	0.5	1.7	0.3	1.8
Trunk fat-free mass	0.9	5.3	29.1	3.8	-2.0	-2.4	-3.0	0.0	0.2	-2.0	-1.9	-0.7	-2.4	0.7	-2.5	-2.1	-0.1	5.4	2.7	-0.2	-2.6	1.0	-2.2	1.8	-2.4
Noisy workplace	0.9	1.1	2.6	1.5	0.7	1.3	1.1	0.4	0.2	0.9	0.5	1.5	1.2	0.3	0.2	0.3	0.5	1.2	0.4	1.5	0.6	1.6	1.2	1.6	1.2
Prospective memory result	0.9	1.1	2.6	0.5	1.3	0.9	0.6	1.2	1.5	0.9	0.7	1.0	1.2	0.9	0.1	0.7	1.5	0.2	-0.6	1.6	0.7	1.5	0.9	1.5	0.9
Tense / ‘highly strung’	0.9	1.4	11.7	-2.6	0.9	0.6	0.4	0.1	-0.2	0.6	0.7	0.5	1.3	0.8	1.2	0.7	0.0	-3.4	-1.8	-0.6	0.6	-1.1	0.3	-1.1	0.3
Medication: Ventolin 100micrograms inhaler	0.9	1.1	4.0	-0.8	-0.9	-1.6	-1.1	-0.5	-0.7	-1.4	-0.9	-1.1	-0.8	0.6	0.2	-0.4	-1.0	0.1	0.5	-1.0	-0.9	-1.7	-2.0	-0.3	-1.8
Qualifications: College or University degree	0.9	2.9	6.0	-0.7	1.7	2.5	1.5	0.6	0.5	2.1	1.8	2.0	2.2	2.4	1.6	1.5	1.0	-1.9	-0.1	1.6	2.1	1.1	2.4	0.5	2.2
Medication: Blood pressure	0.9	1.7	10.0	3.2	-0.0	1.3	0.9	-0.1	-0.1	0.7	0.6	1.7	-0.7	-0.9	-0.7	-0.3	0.3	2.7	0.6	1.5	0.7	1.4	1.6	1.1	1.5
Long-standing illness, disability or infirmity	0.9	1.3	9.8	1.4	0.5	1.0	0.5	0.3	-0.4	0.3	0.6	1.1	0.4	-0.2	0.7	0.4	-0.0	2.2	3.1	1.0	0.9	-0.5	1.1	2.1	1.0
Illnesses of father: None of the above (group 1)	0.9	1.1	2.7	-1.3	1.6	0.6	1.0	0.9	1.0	0.2	1.6	0.8	1.2	1.6	1.2	1.4	1.1	-1.2	1.1	0.8	1.2	-0.0	0.6	0.4	0.7
Pain type(s) experienced in last month: Hip pain	0.9	1.2	7.6	2.3	-0.3	0.1	0.1	-0.3	-0.5	0.2	0.0	0.7	-0.2	-0.6	0.3	0.2	-0.4	2.8	2.6	1.3	0.3	0.6	0.1	1.4	0.1
High cholesterol (Self-reported)	0.9	1.6	6.0	2.1	-1.5	-0.6	-0.6	-1.7	-1.4	-1.1	-0.8	-0.1	-1.5	-1.5	-1.6	-1.5	-1.3	2.4	0.7	-0.7	-1.1	-0.5	-0.5	-0.2	-0.5
Medication: Lisinopril	0.9	1.1	7.8	2.8	-0.4	0.4	0.5	0.7	0.6	-0.3	-0.1	-0.3	-0.6	-0.5	-0.3	0.3	0.5	2.6	1.4	1.1	0.3	1.5	0.5	1.0	0.5
Commuting to job workplace: Cycle	0.9	1.1	3.6	-1.7	1.3	1.2	1.6	0.2	-0.2	1.1	0.2	0.5	1.9	-1.1	1.0	0.5	-0.2	-1.4	0.1	0.7	1.1	-0.8	1.1	0.3	1.2
Schizophrenia (2014)	0.8	1.8	4.7	1.3	-1.7	-0.7	-0.8	-2.2	-2.1	-1.4	-1.5	-0.5	-1.1	-0.7	-1.7	-2.2	-1.8	0.9	0.0	-1.2	-1.5	-0.8	-0.8	-1.4	-0.8
Respiratory disease	0.8	1.9	5.9	0.1	-0.1	-2.1	-1.5	1.9	1.6	-1.0	-0.2	-1.3	-1.0	0.9	0.8	0.8	1.1	2.4	1.8	0.2	-0.7	0.3	-2.2	1.5	-2.0
Other serious medical condition/disability diagnosed by doctor	0.8	1.0	4.4	1.4	0.2	1.5	1.3	0.2	0.1	0.9	0.2	0.9	0.2	-2.1	0.3	0.1	0.2	1.5	1.5	1.0	0.6	0.0	1.4	0.9	1.4
Medication: Metformin	0.8	1.1	7.1	1.2	-1.1	-0.2	-0.4	-1.2	-1.2	-0.7	-1.1	-0.3	-0.3	-0.1	-1.0	-1.0	-1.3	1.8	2.7	-0.3	-0.4	-1.1	-0.1	0.3	-0.2
Serious illness, injury or assault to yourself	0.8	0.9	4.3	1.2	-1.2	-0.2	0.2	-1.0	-1.3	-0.7	-1.0	-0.5	-0.6	-1.1	-0.6	-0.8	-1.3	1.2	2.1	-0.5	-0.4	-1.4	-0.4	-0.0	-0.3
Diverticular disease/diverticulitis (self-reported)	0.8	0.9	2.5	0.5	-1.2	-1.1	-1.0	0.7	0.6	-1.4	-0.9	-1.6	-1.0	-1.3	0.3	0.3	-0.1	1.3	1.2	-0.7	-0.4	-0.5	-1.2	1.0	-1.2
Past tobacco smoking	0.8	1.5	9.6	0.0	-0.5	0.8	0.7	-1.6	-1.3	0.0	-0.7	0.6	0.3	-1.4	-1.2	-1.5	-1.1	-2.0	-2.3	-0.5	-0.4	0.0	0.6	-3.1	0.7
Allergy	0.8	1.8	5.7	-0.5	-0.7	-0.8	-0.9	-1.3	-0.9	-0.9	-1.2	-0.9	-0.7	-1.3	-2.1	-1.8	-0.8	-1.4	-2.2	-1.9	-1.7	-1.1	-1.0	-2.4	-1.0
Pain all over the body in last month	0.8	0.8	3.6	-1.8	0.2	0.5	0.5	-0.8	-1.2	0.4	0.2	-0.3	1.3	0.1	0.6	0.1	-1.0	-1.9	-1.2	-0.8	0.6	-1.4	0.2	-0.8	0.2
Hayfever/allergic rhinitis (self-reported)	0.8	1.0	3.6	0.8	0.5	1.0	1.1	1.2	1.2	1.0	0.3	0.6	0.6	0.4	0.1	0.7	1.0	1.0	1.9	1.4	0.9	0.8	1.0	1.6	1.0
Blood clot in the leg (DVT)	0.8	1.1	3.8	-0.2	-0.7	-0.5	-0.8	-1.8	-1.9	-1.5	-0.8	0.2	-0.2	-0.7	-1.1	-1.5	-1.5	0.4	0.9	-0.8	-0.9	-1.7	-0.4	-0.5	-0.6
Exposure to tobacco smoke outside home	0.8	1.0	4.7	1.1	-1.4	-0.9	-0.8	-0.6	-0.6	-1.2	-0.4	-1.0	-2.2	-1.6	-0.4	-0.4	-0.6	1.5	0.5	-1.1	-1.0	-0.1	-0.9	-0.0	-0.9
Worry too long after embarrassment	0.8	1.3	6.7	-2.1	1.3	0.4	0.4	1.4	1.3	0.6	0.6	-0.8	1.4	1.5	1.2	1.5	0.9	-2.6	-0.2	0.2	0.9	-0.5	0.2	0.2	0.2
Supplements: Calcium	0.8	0.8	6.9	1.4	-0.9	0.1	0.0	-0.9	-0.9	0.1	-0.6	-0.2	-0.8	-2.6	-0.8	-0.9	-0.8	1.6	0.8	-0.3	-0.4	-0.8	0.2	0.1	0.2
Depressed Affect (Nagel 2018)	0.7	1.4	3.5	-0.4	-1.2	-1.8	-1.5	-0.2	-0.3	-1.4	-1.1	-1.7	-1.3	0.0	-0.4	-0.2	-0.8	0.6	1.2	-1.3	-1.1	-1.7	-1.9	0.6	-1.8
Neuroticism (Nagel 2018)	0.7	1.7	5.3	-1.8	-1.1	-1.0	-0.9	-1.3	-1.4	-1.2	-1.2	-1.4	-0.6	-0.8	-0.5	-0.7	-1.7	-1.8	-1.2	-2.0	-0.8	-2.3	-1.2	-1.2	-1.2
Alzheimer’s Disease (including proxy)	0.7	1.0	7.6	0.5	0.4	0.5	0.4	1.1	0.7	0.9	0.7	0.3	0.3	-0.6	1.4	1.4	0.7	0.6	-0.7	1.1	1.3	1.2	0.7	2.8	0.6
Type 2 Diabetes (T2D) (2018)	0.7	1.3	8.0	1.9	-0.5	0.7	0.4	-0.3	-0.4	0.4	0.3	1.3	-0.4	-0.2	0.3	0.3	-0.4	2.8	2.7	1.0	0.9	0.1	1.0	1.7	0.8
Number of treatments/medications taken	0.7	1.3	7.7	2.7	-0.9	0.2	0.1	-0.5	-0.5	-0.2	-0.5	0.3	-1.2	-1.7	-0.6	-0.9	-0.4	2.8	2.4	0.1	-0.5	0.1	0.3	-0.2	0.3
Relative age of first facial hair	0.7	1.4	6.9	-0.0	-1.1	-0.7	-0.8	-1.0	-0.5	-0.4	-1.2	-1.4	-0.3	-1.1	-0.8	-0.9	-0.9	-1.1	-2.6	-0.8	-1.2	1.0	-0.9	-2.6	-0.9
Relative age voice broke	0.7	1.1	5.7	-0.9	1.2	-0.2	0.2	0.7	0.9	0.5	0.5	0.0	1.2	0.5	0.7	0.5	0.8	-1.8	-2.4	0.3	-0.2	1.9	-0.4	-2.1	-0.2
Taking other prescription medications	0.7	1.0	6.2	2.1	-0.8	0.1	-0.0	0.4	0.4	-0.4	-0.7	-0.6	-0.8	-0.8	-0.5	-0.3	0.1	2.5	2.5	-0.2	-0.3	-1.0	-0.0	1.1	-0.0
High blood pressure	0.7	1.9	11.5	3.3	-1.1	0.6	0.1	-0.4	-0.4	0.2	-0.1	1.1	-1.3	-2.0	-0.8	-0.6	-0.2	3.4	-0.4	1.4	0.0	2.4	0.8	0.2	0.7
Mouth/teeth dental problems	0.7	1.0	4.8	-0.8	0.3	1.0	0.6	-1.3	-1.2	0.2	0.1	1.2	0.7	-0.4	-1.0	-1.0	-0.6	-2.1	-1.3	-0.1	-0.0	0.2	0.9	-2.2	0.9
Heart attack	0.7	0.9	3.8	2.0	-1.3	-0.1	-0.6	-0.7	-0.4	-0.5	-1.1	-0.5	-1.0	-0.2	-1.7	-1.4	-0.5	1.4	-0.3	-0.4	-1.1	0.2	-0.2	-0.9	-0.3
Medication: Ramipril	0.7	0.9	4.1	1.9	-1.0	0.0	-0.2	-0.7	-0.5	-0.3	-0.8	0.5	-1.2	-1.6	-1.4	-1.4	-0.5	2.0	1.0	-0.1	-0.8	-0.3	-0.0	0.0	-0.0
Medication: Simvastatin	0.7	1.0	5.1	1.8	-0.8	-1.0	-1.0	0.1	0.5	-0.8	-0.1	-0.3	-1.3	0.5	-0.7	-0.3	0.2	2.2	1.6	-0.2	-0.6	0.6	-0.8	1.6	-0.8
Asthma	0.7	1.4	4.8	0.1	-0.8	-2.0	-1.3	1.3	1.1	-1.0	-0.8	-1.6	-1.3	0.1	0.1	0.3	0.4	1.9	1.6	-0.3	-1.0	-0.4	-2.2	0.3	-2.0
Medication: Paracetamol	0.7	1.2	6.2	2.5	-0.5	1.3	0.8	-1.2	-1.1	0.8	0.2	1.5	-0.1	-1.3	-0.6	-1.0	-0.6	1.9	0.6	0.6	0.3	0.0	1.5	-0.1	1.4
Pulse wave peak to peak time	0.7	0.8	4.9	-0.4	-0.5	0.3	0.1	-0.6	-0.4	0.2	-0.4	-0.6	0.3	-0.7	-0.1	-0.5	-0.6	-2.2	-2.0	-0.3	-0.0	0.8	0.3	-2.1	0.3
Medication: Ibuprofen	0.7	0.9	2.2	1.5	0.6	0.6	0.6	1.0	1.0	1.1	1.0	0.7	0.4	0.1	1.1	1.2	1.0	1.5	0.8	1.3	0.7	1.4	0.6	0.7	0.6
Had major operations	0.7	0.8	3.5	0.8	0.7	1.3	0.8	-0.0	-0.3	0.6	0.7	1.1	0.7	0.5	0.3	0.3	0.2	0.5	1.9	0.9	0.9	-0.0	1.4	1.4	1.3
Leg pain on walking	0.7	0.9	7.0	1.5	-0.4	-0.5	-0.5	1.0	1.1	-0.3	-0.2	-0.2	-0.7	0.5	-0.1	0.3	0.7	2.6	1.5	0.3	-0.4	0.6	-0.6	1.6	-0.6
Commuting to job workplace: Car/motor vehicle	0.7	0.8	2.8	1.7	-0.6	-0.5	-0.8	-0.5	-0.1	-1.1	-0.7	-0.4	-1.3	-1.4	-1.6	-1.2	0.0	1.2	-0.7	-0.2	-1.0	1.2	-0.3	0.2	-0.4
Diabetes diagnosed by doctor	0.7	1.2	7.6	1.9	-1.0	0.6	0.2	-1.1	-1.1	0.1	-0.2	0.7	-0.6	-0.6	-0.1	-0.3	-1.1	2.4	2.8	0.4	0.5	-0.6	0.7	0.9	0.5
Asthma (self-reported)	0.7	1.5	4.9	-0.2	-0.7	-2.0	-1.4	1.4	1.2	-1.1	-0.8	-1.7	-1.2	0.4	0.3	0.5	0.4	1.7	1.6	-0.3	-0.9	-0.5	-2.2	0.5	-2.0
Wears glasses or contact lenses	0.7	0.9	5.6	2.4	-0.4	0.9	0.6	0.1	0.1	0.8	0.4	1.2	-0.5	-0.9	-0.0	0.0	0.3	2.0	0.4	0.9	0.4	0.7	1.0	0.9	0.9
Hearing aid user	0.7	0.8	5.5	2.4	-0.1	0.7	0.8	1.1	1.0	1.1	0.6	1.0	-0.7	-0.3	0.7	0.4	1.1	1.4	0.6	0.4	0.1	1.1	0.4	-0.5	0.5
Average weekly beer plus cider intake	0.7	1.0	3.3	0.4	-0.1	-1.5	-1.6	0.9	0.9	-1.0	-0.3	-0.0	-0.7	0.8	0.1	0.0	0.5	1.6	1.8	-0.4	-0.7	-0.8	-1.2	1.7	-1.3
Vascular/heart problems diagnosed by doctor	0.7	2.0	12.6	-3.5	1.7	-0.2	0.4	0.7	0.6	0.3	0.4	-0.7	1.8	1.8	1.0	0.8	0.5	-3.5	0.5	-0.7	0.4	-2.0	-0.4	-0.2	-0.2
Heart disease (siblings)	0.7	0.8	3.1	0.1	-0.6	-0.5	-0.7	-1.4	-1.4	-0.8	-0.8	-0.1	-0.3	-1.1	-1.1	-1.5	-1.2	0.3	0.6	-1.1	-0.8	-1.8	-0.4	0.3	-0.5
Depression (Nagel 2018)	0.6	0.9	3.5	0.6	-1.0	-0.7	-0.7	-1.8	-1.9	-1.1	-0.7	-0.5	-0.9	-0.3	-1.3	-1.1	-1.6	0.3	0.0	-0.5	-0.8	-0.0	-0.6	-0.6	-0.7
Major Depression (MDD)	0.6	0.7	4.6	1.5	-0.6	-0.1	0.1	0.2	0.6	-0.6	-0.1	-0.3	-0.6	0.6	-0.3	-0.0	0.1	2.1	2.1	0.0	0.1	-0.4	-0.2	1.3	-0.1
Primary Biliary Cirrhosis	0.6	0.8	5.1	0.8	0.8	0.4	0.5	1.0	1.1	0.3	1.0	0.3	0.5	0.9	0.7	0.9	1.1	1.4	0.6	0.3	0.6	-0.8	0.3	2.3	0.3
Blood White Count	0.6	4.2	13.4	0.3	-2.1	-2.6	-2.0	-1.3	-1.5	-2.8	-1.4	-2.1	-2.5	0.1	-0.8	-0.9	-1.8	2.7	3.7	-2.0	-1.3	-2.9	-2.4	0.9	-2.4
Height	0.6	10.8	23.1	1.0	-3.2	-4.5	-4.2	-1.8	-1.3	-4.0	-4.4	-3.7	-3.2	-1.2	-4.1	-4.1	-2.1	2.3	0.8	-3.0	-4.8	-1.5	-4.7	-1.4	-4.5
Neuroticism	0.6	1.3	7.0	-1.6	-0.7	-1.1	-0.9	-0.4	-0.6	-1.1	-0.9	-1.6	-0.6	-0.1	0.0	-0.1	-0.9	-1.4	-0.8	-1.9	-0.8	-2.6	-1.4	-0.6	-1.3
Average weekly spirits intake	0.6	0.7	2.3	0.2	-0.6	-1.0	-0.8	-0.1	0.1	-1.4	-0.8	-0.8	-0.7	0.0	-0.6	-0.7	-0.0	0.8	1.1	-1.0	-1.2	-1.5	-1.3	0.3	-1.2
Medication: Co-codamol	0.6	0.7	2.0	-1.0	1.0	0.4	0.3	0.5	0.3	0.5	0.7	0.9	0.7	-1.0	1.1	1.0	0.3	-0.3	-0.5	1.3	1.1	1.0	0.8	1.4	0.7
Hand grip strength (right)	0.6	1.6	6.8	1.3	0.8	0.4	-0.1	1.4	1.5	0.9	0.4	1.0	0.6	1.5	-0.5	0.2	1.6	2.0	0.2	2.3	0.4	2.6	0.5	1.9	0.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.6	0.8	2.0	0.1	-1.0	-1.2	-1.4	-1.1	-1.3	-1.3	-0.7	-0.9	-1.1	0.4	-0.4	-0.6	-1.2	0.4	-0.6	-0.8	-0.8	-0.4	-1.1	0.1	-1.2
Qualifications: CSEs or equivalent	0.6	0.8	2.6	0.4	-0.7	-0.8	-1.5	-1.4	-1.6	-0.5	-0.4	0.5	-0.7	0.1	-1.2	-1.2	-1.1	-0.2	-1.2	-0.7	-0.9	0.0	-0.4	-0.6	-0.7
Medication: Atenolol	0.6	0.7	2.5	1.6	0.3	0.6	0.3	0.9	1.1	0.6	0.5	0.8	0.1	0.7	0.2	0.5	1.0	1.0	1.0	1.2	0.5	1.2	0.7	0.9	0.7
Diabetes (self-reported)	0.6	1.0	7.8	1.3	-0.6	0.5	0.4	-1.1	-1.2	0.2	-0.0	1.1	-0.4	-0.7	-0.0	-0.4	-1.0	1.8	2.8	0.3	0.4	-0.9	0.6	0.7	0.6
Time employed in main current job	0.6	0.7	2.3	0.2	-0.2	-1.0	-1.0	0.2	0.6	-1.0	-0.5	-0.7	-0.7	1.5	-0.9	-0.6	0.4	-0.2	-0.7	-1.1	-1.2	-0.7	-1.0	-1.2	-1.0
Medication: Ibuprofen (e.g. Nurofen)	0.6	0.7	1.6	1.1	0.6	0.6	0.9	1.1	1.2	1.1	0.7	0.4	0.5	-0.4	1.0	1.0	1.1	1.1	0.3	1.1	0.6	1.2	0.5	0.2	0.7
Medication: Cholesterol lowering	0.6	1.0	6.8	2.4	-0.8	-0.4	-0.6	-0.6	-0.4	-0.4	-0.3	0.5	-1.2	-1.0	-1.0	-0.8	-0.4	2.6	1.2	0.3	-0.6	0.3	-0.3	1.0	-0.3
Illnesses of mother	0.6	0.7	2.0	-0.8	0.6	0.3	0.6	1.2	1.2	0.3	1.0	0.1	-0.1	1.0	1.4	1.3	1.1	-0.0	1.1	-0.4	0.7	-1.4	0.4	0.4	0.4
Pulse wave Arterial Stiffness index	0.6	0.7	4.8	0.3	0.2	-0.6	-0.4	0.4	0.2	-0.5	0.0	0.3	-0.5	0.5	-0.2	0.1	0.3	2.2	1.9	-0.0	-0.4	-1.1	-0.7	2.0	-0.6
Birth weight	0.6	1.3	3.6	0.3	-1.0	-1.0	-0.7	-1.0	-0.7	-1.6	-1.4	-1.3	-1.4	-1.1	-1.9	-1.8	-0.7	0.2	-0.7	-0.8	-1.6	0.3	-1.0	-1.3	-0.9
Neck or shoulder pain in last month	0.6	0.9	1.8	1.2	0.6	0.9	0.9	0.9	0.8	0.9	1.1	1.3	-0.1	-0.8	0.8	0.7	1.0	1.0	0.9	1.1	0.8	0.9	1.2	0.9	1.1
Alcohol intake frequency.	0.6	1.4	8.6	-1.0	-0.1	1.0	1.3	-1.3	-1.3	0.8	-0.4	-0.4	0.8	-1.3	-0.1	-0.5	-1.3	-2.7	-0.9	-0.5	0.4	-0.7	0.8	-2.9	0.9
Overall health rating	0.6	1.4	8.8	2.4	-0.4	0.3	-0.0	-0.4	-0.6	-0.4	0.4	1.1	-0.9	-0.6	-0.5	-0.3	-0.1	3.0	2.9	0.9	0.4	-0.2	0.6	1.3	0.4
Age at last live birth	0.6	0.9	2.4	-1.4	1.2	1.1	0.5	0.6	0.8	1.1	0.6	1.0	1.4	0.6	0.3	0.5	0.8	-1.5	0.3	0.8	0.8	0.3	1.3	0.9	1.1
Supplements: Vitamin C	0.6	0.7	3.2	0.6	-1.0	-1.1	-1.1	-0.2	0.1	-0.7	-0.7	-0.9	-1.8	-0.9	-0.7	-0.7	-0.1	0.6	-0.8	-1.2	-1.1	-0.2	-1.0	-0.3	-1.0
Knee pain experienced in last month	0.6	0.9	4.4	1.7	-1.0	-1.1	-0.9	0.6	0.7	-0.9	-0.5	-1.1	-1.3	-0.7	-0.2	0.2	0.1	2.1	0.5	-0.1	-0.6	0.9	-0.8	0.9	-0.9
Hypertension (Self-reported)	0.6	1.7	9.7	3.1	-1.3	0.4	-0.1	-0.6	-0.6	0.1	0.0	1.1	-1.3	-1.7	-0.5	-0.4	-0.4	3.1	-0.7	1.3	0.1	2.4	0.7	0.0	0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.6	0.7	2.8	0.1	0.9	0.9	1.1	0.8	0.6	0.5	0.9	0.2	0.7	0.2	0.5	0.9	0.7	0.7	1.7	0.7	1.1	-0.5	0.9	1.2	1.0
Average weekly red wine intake	0.6	1.0	2.7	-0.2	0.8	0.3	0.0	1.4	1.6	0.4	1.0	-0.2	-0.3	1.4	0.3	1.2	1.5	0.4	1.1	1.2	1.0	1.6	0.7	1.2	0.5
Ever had bowel cancer screening	0.6	0.7	2.1	0.9	0.4	1.1	1.3	1.1	1.1	1.4	0.4	0.4	0.2	-0.0	0.5	0.7	0.9	0.7	0.8	0.9	0.6	-0.2	0.8	0.2	1.0
Tinnitus: Yes, now most or all of the time	0.6	0.7	2.5	-0.9	0.7	1.0	0.5	-0.2	-0.5	1.1	0.5	1.6	1.4	-0.0	0.3	0.2	-0.3	-0.4	0.0	1.4	1.0	0.3	1.1	1.4	1.0
Medication: Paracetamol	0.6	0.9	6.4	2.5	-0.8	0.5	0.2	-1.1	-1.0	0.2	-0.1	0.8	-0.8	-1.0	-0.9	-1.2	-0.5	1.9	0.3	-0.2	-0.4	0.1	0.7	-0.5	0.6
Alcohol drinker status: Never	0.6	0.8	3.8	-0.2	-1.0	-0.3	0.0	-0.8	-0.7	-0.4	-0.9	-0.6	-0.9	-1.2	-0.7	-0.6	-0.8	-1.1	-1.9	-0.9	-0.6	-0.5	-0.6	-1.7	-0.4
Risk taking	0.6	0.9	6.0	2.4	-0.4	-0.8	-0.9	0.5	0.8	-0.2	0.0	0.2	-1.4	0.9	-0.4	-0.4	0.8	1.8	0.9	0.3	-0.8	1.4	-0.7	-0.1	-0.7
Ever depressed for a whole week	0.6	0.8	2.1	-1.4	1.2	0.7	0.7	0.6	0.2	0.4	1.2	0.4	1.1	0.9	1.2	1.2	0.5	-1.3	0.4	0.1	1.2	-0.6	0.8	0.7	0.7
Medication: Omeprazole (e.g. Zanprol)	0.6	0.7	3.0	0.9	-0.6	0.0	0.2	0.1	-0.1	-0.8	-0.8	-1.3	-0.2	-0.1	-0.3	-0.1	-0.4	1.7	1.7	-0.7	-0.0	-1.6	-0.1	1.7	-0.0
Heart attack/myocardial infarction (self-reported)	0.6	0.8	4.0	2.0	-1.2	-0.0	-0.5	-0.7	-0.3	-0.5	-1.1	-0.4	-1.0	-0.2	-1.7	-1.4	-0.4	1.2	-0.3	-0.3	-1.0	0.3	-0.1	-1.0	-0.2
Schizophrenia vs Biploar Disorder	0.5	0.6	2.3	0.7	-0.7	-0.5	-1.1	-1.5	-1.2	-0.7	-0.7	0.2	-0.6	0.2	-1.2	-1.3	-0.9	-0.4	0.0	-0.6	-0.9	0.6	-0.2	0.1	-0.4
Alzheimer’s Disease (in mother)	0.5	0.6	5.6	0.4	-0.5	-0.6	-0.5	0.4	0.1	-0.5	-0.3	-0.6	-0.5	-0.8	0.7	0.4	-0.2	1.2	-1.4	-0.2	0.3	0.3	-0.3	2.4	-0.4
Coronary Artery Disease (CAD)	0.5	0.6	1.6	-0.9	-0.6	-0.8	-0.7	-0.2	-0.1	-1.1	-0.9	-1.0	-0.6	0.6	-0.2	-0.8	-0.3	-0.6	0.6	-1.1	-0.9	-1.3	-0.9	-0.7	-0.9
Crohns Disease (2012)	0.5	0.8	7.1	1.5	-0.8	-0.7	-0.5	-0.3	-0.2	-0.6	-1.0	-1.1	-0.6	-0.1	-0.7	-0.6	-0.6	2.7	0.0	0.1	-0.7	-0.4	-1.1	0.3	-0.9
HbA1C	0.5	0.6	4.1	1.0	0.2	-0.2	0.1	0.7	0.6	0.4	0.2	0.6	0.2	0.7	0.2	0.1	0.5	1.6	1.1	1.0	0.3	0.0	0.0	2.0	0.0
Type 2 Diabetes (T2D) (2012)	0.5	0.6	1.7	1.3	0.2	1.2	1.0	0.5	0.1	0.8	0.4	1.0	0.6	0.4	-0.1	0.1	0.7	0.2	-0.4	0.9	0.7	0.8	1.0	0.7	1.1
Blood Eosinophil Count	0.5	3.6	6.3	1.6	-2.3	-1.6	-1.2	-1.6	-1.2	-2.0	-2.0	-2.5	-2.2	-0.8	-2.4	-2.1	-1.4	1.5	1.9	-2.5	-2.0	-2.1	-1.8	-1.8	-1.7
Lung FEV1/FVC ratio	0.5	2.5	13.4	3.7	-0.0	1.3	0.6	-0.5	0.2	1.0	0.5	2.8	-0.8	-0.5	-1.9	-1.7	1.1	0.3	-2.0	0.4	-0.7	2.4	1.7	-2.6	1.5
Tanning	0.5	6.0	44.0	-0.6	0.3	-1.5	-1.4	2.0	1.5	-0.9	0.2	-0.4	-0.4	0.5	2.0	1.5	0.9	4.9	5.9	1.1	0.7	-2.0	-1.1	6.6	-1.3
Medication for hormone replacement therapy	0.5	0.6	1.6	1.3	0.5	0.6	0.7	0.5	0.4	0.3	1.3	1.0	0.2	0.6	0.8	0.8	0.7	1.0	0.8	0.8	0.8	1.0	0.8	0.6	0.7
Fed-up feelings	0.5	1.0	12.5	0.8	-0.4	-0.3	0.2	-0.4	-0.5	-0.5	-0.4	0.1	-0.2	0.3	-0.3	-0.5	-0.5	1.8	3.5	-0.3	-0.4	-1.8	-0.4	0.5	-0.3
High blood pressure (mother)	0.5	0.6	2.2	1.4	-0.3	0.4	-0.0	-0.7	-0.9	0.3	-0.3	1.2	0.1	-0.8	-0.7	-0.8	-0.7	1.3	1.5	1.1	-0.1	1.0	0.5	0.3	0.4
Impedance of leg (left)	0.5	2.4	15.6	-2.6	1.1	1.4	2.1	-0.3	-0.5	0.9	1.2	-0.3	1.4	-0.2	1.7	1.4	-0.3	-4.0	-1.8	-0.1	1.6	-0.4	1.0	-1.9	1.2
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.8	2.6	-1.2	-0.6	-0.9	-1.0	-0.8	-1.1	-0.6	-0.7	-0.6	-0.1	-0.2	-0.1	-0.5	-1.2	-1.1	-0.4	-1.1	-0.6	-1.6	-1.0	-0.6	-1.1
Financial difficulties in last 2 years	0.5	0.6	1.9	-0.7	1.3	0.3	0.6	1.1	0.9	0.5	0.8	0.4	1.4	0.9	0.6	0.9	1.0	0.1	1.1	0.9	0.7	0.1	0.2	0.9	0.3
Neuroticism score	0.5	1.0	5.7	-2.3	0.3	-0.0	0.2	0.0	-0.4	0.1	0.1	-0.4	0.6	0.3	1.0	0.7	-0.4	-2.4	-0.8	-1.0	0.3	-2.4	-0.3	-0.6	-0.3
Impedance of arm (right)	0.5	2.4	18.7	-3.2	0.7	0.2	1.1	-0.1	-0.0	0.4	0.4	-1.4	0.8	-0.4	1.1	1.0	-0.2	-4.3	-3.0	-1.1	0.5	-0.6	-0.0	-2.6	0.2
Father’s age at death	0.5	0.7	2.4	0.8	0.4	1.3	1.3	0.4	0.4	1.3	0.1	0.4	0.7	-0.5	0.0	0.0	0.5	-1.6	-0.9	0.6	0.3	1.2	0.8	-1.2	1.0
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.9	3.7	1.6	-0.5	0.6	0.5	-1.7	-1.9	-0.3	-0.0	1.2	0.5	-0.3	-0.7	-1.1	-1.3	1.1	1.2	0.3	-0.0	-0.2	0.4	-0.5	0.4
Pulse rate	0.5	0.8	3.6	0.0	0.5	0.1	-0.6	-1.1	-1.0	-0.4	0.4	1.8	0.2	1.9	-1.3	-0.9	-0.3	0.1	1.9	0.2	-0.1	-1.1	0.5	0.2	0.2
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.6	2.9	-0.2	1.1	0.3	0.3	0.3	0.2	0.7	0.7	1.1	0.8	-0.4	0.5	0.5	0.3	0.7	1.7	1.1	0.6	-0.0	0.6	1.7	0.5
Impedance of arm (left)	0.5	2.3	18.0	-3.0	0.8	0.7	1.4	-0.3	-0.1	0.7	0.3	-1.1	1.2	0.0	0.9	0.8	-0.3	-4.2	-2.5	-0.9	0.6	-0.6	0.3	-2.5	0.6
Gout (self-reported)	0.5	0.7	2.3	0.5	-1.1	-0.9	-0.7	-0.5	-0.4	-1.5	-0.6	-0.8	-1.5	-0.9	-0.2	-0.3	-0.7	1.1	1.3	-0.9	-0.5	-0.4	-0.6	0.8	-0.7
High blood pressure (siblings)	0.5	0.8	5.4	2.3	-1.1	-0.2	-0.1	-0.3	-0.4	-0.7	-0.7	-0.3	-0.9	-0.9	-0.5	-0.6	-0.5	2.3	1.1	-0.2	-0.3	0.1	-0.0	0.6	-0.0
Medication: Seretide 50 evohaler	0.5	0.5	2.2	-0.2	-0.8	-0.2	-0.3	0.1	0.1	-0.6	-0.2	-0.9	-1.5	-1.1	-0.2	-0.1	-0.1	-0.9	-1.4	-1.2	-0.3	-0.2	-0.2	-1.4	-0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.6	4.2	0.7	-0.1	0.4	0.4	1.1	1.1	0.6	-0.0	-0.2	-1.0	0.8	-0.2	0.3	1.0	0.7	-0.7	0.9	0.0	2.1	0.3	-0.7	0.4
Family relationship satisfaction	0.5	0.6	2.6	0.2	0.4	-0.4	-0.4	1.2	1.3	-0.5	0.6	-0.1	-0.7	1.4	-0.0	0.5	1.3	1.1	0.4	-0.2	0.1	-0.3	-0.1	1.6	-0.2
Medication: Aspirin	0.5	0.6	1.6	0.9	-0.9	-0.7	-0.6	-1.2	-1.1	-0.8	-0.5	-1.1	-0.8	-0.1	-0.8	-0.6	-1.2	0.4	-0.0	-0.9	-0.5	-0.2	-0.6	-0.8	-0.6
Illnesses of father: Heart disease	0.5	0.7	3.1	-0.3	0.9	0.6	0.2	1.2	1.3	1.4	0.5	0.3	0.6	0.1	0.3	0.6	1.2	-0.1	-1.8	1.0	0.4	1.3	0.8	0.4	0.7
Eye problems/disorders: Cataract	0.5	0.6	3.1	1.3	-0.9	-0.3	-0.2	0.7	0.7	-0.3	-0.3	-0.6	-1.5	0.3	-0.2	0.2	0.5	1.8	0.3	0.1	-0.3	1.0	-0.5	0.8	-0.4
Guilty feelings	0.5	0.7	2.5	-1.5	-0.0	0.1	0.2	-0.6	-1.2	-0.1	0.4	-0.4	0.6	-0.4	1.4	0.9	-1.2	-1.4	0.7	-0.6	1.0	-1.6	0.0	0.4	-0.0
Ever taken oral contraceptive pill	0.5	0.6	2.5	0.8	0.6	-0.5	-0.5	1.1	1.1	0.4	0.6	0.7	-0.1	-0.2	0.2	0.3	1.2	1.1	1.6	0.7	-0.2	0.6	-0.5	0.7	-0.4
Commuting to job workplace: Public transport	0.5	0.6	3.3	0.0	0.2	0.9	0.7	-0.4	-0.5	0.6	0.4	1.1	0.8	0.5	0.2	-0.1	-0.2	-1.8	-1.2	0.3	0.5	0.2	0.8	-1.5	0.8
Cholesterol lowering medication	0.5	0.8	2.2	1.2	-1.3	-1.0	-1.2	-0.5	-0.4	-1.1	-0.7	-0.8	-1.2	-0.3	-0.9	-0.7	-0.7	1.5	-0.3	-0.7	-0.8	0.5	-0.8	0.5	-0.9
Impedance of whole body	0.5	2.5	19.1	-3.1	0.3	0.4	1.2	-0.9	-0.8	0.1	0.0	-1.5	0.7	-0.8	0.9	0.6	-0.9	-4.4	-2.6	-1.2	0.5	-1.0	-0.1	-2.9	0.2
Irritable Bowel Disease (IBD)	0.4	0.9	7.3	2.1	-0.7	0.0	0.2	-0.6	-0.8	0.2	-0.6	0.1	-0.4	-1.4	-0.2	-0.6	-0.7	2.7	0.8	0.6	-0.2	0.4	0.1	1.1	0.1
Ulcerative Colitis (UC)	0.4	0.8	2.9	1.0	0.1	1.2	1.2	-0.1	-0.4	1.0	0.5	1.1	0.3	-1.7	0.7	0.4	-0.1	0.9	-0.4	1.0	0.9	0.7	1.5	0.8	1.4
HDL Cholesterol	0.4	0.6	4.5	-1.4	-0.4	-0.2	-0.4	-0.3	-0.8	-0.1	0.6	0.0	-0.3	-1.1	2.1	1.1	-0.8	-0.5	-0.6	-0.5	0.5	-0.7	-0.2	0.5	-0.4
Triglycerides	0.4	0.6	3.8	0.0	1.2	0.1	-0.2	0.9	0.9	0.3	0.5	1.2	0.7	2.0	-0.3	-0.1	1.1	0.8	0.7	0.8	-0.1	0.4	0.3	1.1	0.2
Systolic Blood Pressure	0.4	2.1	6.7	2.6	0.7	1.8	1.4	0.4	0.9	1.2	0.8	2.4	0.2	-1.6	-0.9	-0.5	1.4	1.7	-0.3	1.6	0.3	2.0	2.1	0.2	2.0
Hair Pigment	0.4	10.8	49.1	-2.0	-1.5	0.4	-0.2	-4.7	-4.5	-0.9	-1.5	-1.7	0.5	-1.6	-1.8	-2.5	-3.9	-7.0	-6.5	-3.4	-1.0	-1.3	0.5	-7.0	0.3
Ever had hysterectomy (womb removed)	0.4	0.5	4.8	2.2	-0.7	0.5	1.0	-0.3	-0.1	-0.3	-0.1	-0.9	-0.3	-0.8	-0.1	0.1	-0.3	1.0	1.0	-0.0	0.2	0.1	0.2	-0.6	0.4
Age when periods started (menarche)	0.4	1.0	7.3	0.3	-0.4	0.7	0.9	-1.4	-1.5	0.0	0.0	0.1	0.4	-0.1	-0.3	-0.7	-1.1	-1.7	-1.2	-0.8	-0.3	0.8	0.3	-2.7	0.4
Stomach or abdominal pain in last month	0.4	0.5	4.1	0.2	0.2	0.5	0.1	-0.9	-0.9	0.1	-0.2	0.4	0.7	-0.2	-0.2	-0.7	-0.7	0.1	2.0	-0.0	-0.0	-1.5	0.6	0.0	0.5
Hair/balding pattern: Pattern 2	0.4	0.4	2.8	-1.3	0.4	-0.2	-0.1	-0.2	-0.6	-0.1	0.7	0.6	0.5	0.6	1.0	0.3	-0.3	-1.7	-1.1	-0.4	0.2	0.4	-0.2	-0.7	-0.2
Had other major operations	0.4	0.4	2.2	-0.0	0.2	0.9	0.4	-0.3	-0.3	0.7	0.2	0.3	0.8	-1.1	0.3	0.3	-0.4	-0.1	-1.1	1.0	0.6	1.5	0.8	-0.0	0.6
Qualifications: A levels/AS levels or equivalent	0.4	0.9	3.9	-1.6	1.2	0.0	-0.3	1.7	2.0	0.9	0.4	0.5	1.2	0.7	0.4	0.7	1.7	-1.0	-1.3	0.3	-0.1	0.5	0.0	0.2	-0.0
Seen doctor (GP) for nerves, anxiety, tension or depression	0.4	0.6	2.6	-0.5	0.1	0.7	-0.0	-0.5	-0.9	0.4	0.9	0.9	0.8	-0.2	1.6	0.6	-0.7	-1.0	-0.2	-0.6	0.7	-1.5	0.7	-0.4	0.5
Ever highly irritable/argumentative for 2 days	0.4	0.5	1.3	-0.8	-0.3	-1.1	-1.1	-0.2	-0.1	-0.9	-0.7	-1.1	-0.7	0.7	-0.4	-0.5	-0.3	0.5	-0.1	-0.8	-1.0	-0.3	-1.1	0.2	-1.1
Mouth/teeth dental problems: Bleeding gums	0.4	0.5	2.7	-0.3	-0.3	-0.9	-0.1	0.6	0.4	-0.4	-0.2	-1.4	-0.2	0.1	1.0	0.8	-0.1	0.5	1.7	-0.4	-0.0	-0.5	-1.1	0.1	-0.9
Medication: Amlodipine	0.4	0.5	1.8	0.7	-1.0	-0.4	-0.3	-1.1	-1.2	-0.5	-1.0	-0.4	-0.3	-0.9	-0.5	-1.0	-1.3	0.5	0.4	-0.4	-0.4	-0.4	-0.4	-0.2	-0.3
Shortness of breath walking on level ground	0.4	0.5	1.7	1.2	-0.9	-0.7	-0.8	-0.7	-0.7	-0.8	-0.3	-0.4	-0.8	-0.5	-0.1	-0.5	-0.6	1.3	-0.0	-0.6	-0.7	0.5	-0.8	-0.8	-0.8
Medication for pain relief, constipation, heartburn	0.4	0.8	6.2	-2.5	0.8	-0.7	-0.5	0.8	0.6	-0.3	0.2	-0.0	0.3	1.2	0.3	0.5	0.6	-2.1	-0.1	-0.2	-0.1	-0.3	-0.8	0.1	-0.7
Comparative height size at age 10	0.4	2.3	5.1	2.0	-2.1	-1.2	-1.1	-0.6	-0.2	-1.5	-2.2	-2.1	-1.7	-0.8	-2.2	-1.9	-0.8	1.8	0.1	-1.2	-2.1	0.1	-1.6	-0.5	-1.5
Ever had stillbirth, spontaneous miscarriage or termination	0.4	0.4	3.6	1.9	0.1	0.4	-0.2	0.1	0.4	0.1	0.1	0.6	0.2	0.4	-0.3	-0.4	0.5	0.8	0.9	0.5	-0.4	1.3	0.5	-0.5	0.3
Friendships satisfaction	0.4	0.5	2.3	0.3	-0.2	-0.8	-0.5	0.3	0.4	-1.0	-0.0	-0.4	-1.5	0.5	-0.8	-0.3	0.5	1.5	0.5	-0.4	-0.3	-1.0	-0.4	1.1	-0.5
Qualifications: nursing, teaching	0.4	0.6	2.7	-0.4	0.5	-0.2	0.0	1.2	0.8	0.9	0.4	-0.1	0.4	1.6	0.8	0.9	0.7	0.9	0.2	0.6	0.1	0.7	-0.6	1.5	-0.4
Medication: Aspirin	0.4	0.5	1.1	1.0	-0.9	-0.7	-0.4	-1.0	-0.9	-0.7	-0.4	-1.1	-0.9	0.1	-0.7	-0.5	-1.0	0.6	0.4	-1.0	-0.5	-0.6	-0.7	-0.7	-0.6
Average weekly champagne plus white wine intake	0.4	0.5	2.8	0.2	0.4	1.1	0.9	-0.7	-0.6	0.5	0.1	0.8	0.5	-0.4	-0.7	-0.7	-0.1	-0.8	-0.4	0.2	0.0	0.2	0.9	-1.7	0.9
Medication: Blood pressure	0.4	0.8	3.8	1.0	-0.1	1.1	0.8	-0.4	-0.6	0.6	0.6	1.5	0.2	-0.5	0.5	0.5	-0.3	0.9	-0.3	1.4	1.0	1.9	1.2	0.2	1.1
Medication: Bendroflumethiazide	0.4	0.6	4.9	1.1	-0.5	-0.1	-0.3	0.4	0.2	-0.5	0.2	0.2	-1.1	0.5	0.0	0.3	0.2	2.2	0.4	0.6	0.4	0.9	0.2	1.9	0.1
Illnesses of father: High blood pressure	0.4	0.5	2.4	0.9	-1.0	0.0	-0.4	-0.3	-0.4	0.2	-1.2	-0.4	-0.4	-1.6	-1.0	-0.9	-0.6	1.2	0.2	-0.3	-0.8	-0.2	-0.0	0.1	-0.1
Ever had prostate specific antigen (PSA) test	0.4	0.5	1.4	0.7	0.4	1.2	1.1	0.7	0.6	0.4	0.5	-0.1	0.6	0.2	0.5	0.7	0.6	0.1	-0.3	0.8	0.9	0.7	1.1	0.5	1.1
Diastolic blood pressure, automated reading	0.4	1.3	6.9	2.4	-0.6	-0.5	-0.7	0.4	0.9	-0.4	-0.3	0.4	-1.6	-0.6	-1.5	-0.7	0.9	2.6	-0.8	0.7	-0.9	2.4	-0.2	-0.1	-0.3
Myopia	0.4	0.6	2.1	1.0	0.3	1.3	1.1	-0.3	-0.2	1.0	0.4	0.7	0.5	-0.2	-0.0	0.2	0.0	0.2	0.6	1.1	0.9	0.5	1.5	0.3	1.4
Pain experienced in last month	0.4	0.7	4.8	-1.6	0.6	-0.0	-0.1	-0.2	-0.3	0.0	-0.0	0.0	0.8	1.9	-0.3	-0.2	-0.2	-2.2	-1.0	-0.1	0.0	0.4	-0.2	-1.3	-0.2
Intelligence (Savage-Jansen 2018)	0.3	1.0	4.4	0.5	1.2	0.8	0.4	0.7	0.4	0.5	0.9	1.4	0.6	2.1	0.0	0.3	0.8	1.0	1.0	1.3	0.9	0.1	1.1	2.0	1.0
Bipolar Disorder (2011)	0.3	0.3	2.0	-0.4	-0.1	0.1	0.5	-0.9	-1.1	-0.5	-0.1	-0.1	0.2	0.1	0.1	-0.4	-0.9	0.2	0.0	-0.4	-0.0	-1.4	-0.3	-0.6	-0.1
Cardiovascular Disease	0.3	0.9	5.5	2.3	-0.4	0.8	0.5	-0.6	-0.6	0.1	0.3	0.9	-0.0	-1.2	-0.4	-0.3	-0.4	2.4	0.4	0.9	0.3	1.0	0.8	0.2	0.7
Hypothyroidism (self reported)	0.3	0.6	3.5	1.8	-0.2	0.4	0.3	0.5	0.5	-0.1	-0.3	-0.1	-0.5	0.9	-0.8	-0.5	0.6	1.9	0.7	0.8	-0.0	1.0	0.2	1.1	0.3
Chronotype (morning person)	0.3	0.8	4.2	-0.6	-0.1	0.3	-0.2	0.2	0.1	0.7	-0.2	0.1	0.4	1.8	-0.0	-0.2	0.1	-1.9	-2.1	-0.5	-0.1	0.2	0.4	-1.9	0.3
Impedance of leg (right)	0.3	1.6	12.1	-2.1	1.0	1.1	1.7	-0.1	-0.2	0.7	0.9	-0.5	1.0	-0.2	1.2	1.2	0.0	-3.5	-1.5	-0.2	1.2	-0.4	0.7	-1.8	0.9
Hair/balding pattern: Pattern 3	0.3	0.4	1.4	0.3	-0.4	-0.7	-0.9	0.0	0.6	0.1	-0.8	-0.0	-0.6	-0.4	-1.2	-0.9	0.4	0.3	0.0	-0.4	-1.0	-0.9	-0.7	-0.0	-0.7
Happiness	0.3	0.4	1.1	0.4	0.6	0.9	1.0	-0.5	-0.5	0.3	0.7	0.8	0.4	0.5	-0.3	-0.1	0.1	0.1	-0.7	0.4	0.5	-0.0	1.1	0.0	1.0
Depression (self-reported)	0.3	0.3	1.4	1.2	-1.0	-0.3	-0.5	-0.3	-0.7	-0.3	0.3	-0.1	-0.9	-0.7	0.9	0.3	-0.7	0.4	0.7	-0.7	0.2	-0.1	-0.3	-0.2	-0.4
Standing height	0.3	3.3	7.8	0.5	-1.8	-2.3	-2.5	-1.1	-0.7	-2.1	-2.5	-2.1	-1.4	0.3	-2.4	-2.4	-1.2	0.8	0.2	-1.7	-2.8	-0.2	-2.5	-1.1	-2.5
Length of working week for main job	0.3	0.3	1.2	-0.6	0.2	-0.9	-0.4	0.6	0.6	-0.4	-0.2	-0.8	-0.1	-0.6	0.1	0.2	0.3	0.7	-0.3	-0.1	-0.6	0.1	-1.1	0.4	-1.0
Hypothyroidism/myxoedema (self-reported)	0.3	0.7	2.7	1.3	0.2	0.7	0.7	1.1	1.1	0.4	0.2	0.1	-0.1	1.2	-0.2	0.1	1.1	1.7	0.8	0.6	0.4	0.1	0.4	1.6	0.5
Eye problems/disorders: None of the above	0.3	0.4	1.3	-0.5	1.0	0.8	0.7	0.1	0.4	0.3	0.5	0.2	1.0	0.3	0.0	0.1	0.5	-1.2	0.5	-0.0	0.4	-1.0	0.9	-0.6	0.8
Migraine (self-reported)	0.3	0.4	1.4	0.8	0.4	0.7	0.7	0.3	0.6	0.6	-0.3	0.3	0.5	0.7	-0.5	-0.4	0.5	1.0	-0.0	0.9	-0.2	1.2	0.4	-0.8	0.6
Illnesses of siblings: Diabetes	0.3	0.4	1.9	1.3	-0.4	0.1	0.1	-0.2	-0.2	-0.1	-0.9	-0.3	0.0	-0.2	-0.8	-1.0	-0.3	1.4	1.2	0.0	-0.5	-0.2	0.0	0.2	0.1
Miserableness	0.3	0.5	3.8	-0.6	-0.5	-0.9	-0.4	-0.2	-0.4	-0.7	-0.3	-0.9	-0.5	0.3	0.1	0.3	-0.6	-0.0	1.2	-0.7	-0.1	-1.9	-1.0	0.4	-0.9
Financial situation satisfaction	0.3	0.3	1.9	-0.3	-0.4	0.1	0.1	-1.1	-1.0	-0.4	-0.2	-0.0	0.1	-1.4	-0.1	-0.2	-1.1	0.2	0.4	-0.2	0.1	-1.1	0.3	-0.1	0.2
Number of operations (self-reported)	0.3	0.5	3.1	1.8	-1.0	0.7	0.2	-0.8	-0.7	-0.0	-0.7	-0.5	-0.3	-0.9	-0.5	-0.5	-0.9	0.6	0.7	0.1	0.1	0.6	0.6	-0.2	0.5
Irritability	0.3	0.5	3.9	-0.6	0.0	0.0	0.6	-0.9	-1.1	-0.0	-0.1	-0.1	-0.1	0.1	-0.1	-0.3	-0.6	-1.1	-0.8	-0.7	-0.3	-1.3	-0.2	-2.0	-0.0
Age started oral contraceptive pill	0.3	0.3	1.1	-0.0	-0.1	1.0	0.5	-0.5	-0.5	0.7	-0.4	0.1	0.3	-0.9	-0.4	-0.4	-0.5	-1.1	0.2	-0.0	0.1	0.0	0.9	-0.9	0.8
Basal cell carcinoma (self-reported)	0.3	0.4	3.6	0.5	0.6	0.0	-0.2	0.3	0.3	0.3	0.8	0.3	0.5	0.4	0.4	0.4	0.5	-0.3	-1.3	0.6	0.2	1.9	0.2	-0.3	0.1
Lupus	0.2	0.3	1.4	-1.0	0.9	0.2	-0.3	0.2	0.2	0.3	-0.0	0.1	0.5	0.0	-0.4	-0.2	0.3	-1.2	-0.5	0.7	0.0	0.8	0.3	0.1	0.2
Sensitivity / hurt feelings	0.2	0.4	2.0	0.1	-0.9	-0.3	-0.1	-0.6	-0.9	-0.5	-0.8	-0.4	-0.5	-0.8	-0.4	-0.6	-1.0	0.2	0.0	-0.8	-0.5	-1.4	-0.4	-0.3	-0.4
Townsend deprivation index at recruitment	0.2	0.3	1.3	-0.3	0.0	-1.1	-0.9	0.6	0.7	-0.4	-0.1	-0.2	-0.9	0.1	-0.4	-0.0	0.7	0.0	0.3	-0.4	-0.7	-0.4	-1.0	0.1	-1.0
Average weekly fortified wine intake	0.2	0.2	1.2	0.4	-0.3	0.0	-0.3	-0.1	-0.4	0.0	0.4	0.2	0.1	0.7	0.8	0.3	-0.2	0.2	-1.1	0.1	0.1	1.1	-0.1	-0.1	-0.2
Supplements: Glucosamine	0.2	0.2	1.1	0.7	-0.3	-0.5	-0.4	-0.2	-0.1	0.1	-0.5	-0.2	-0.4	0.1	-0.4	-0.7	-0.0	0.8	1.0	-0.4	-0.7	-0.5	-0.4	0.1	-0.4
Hair/balding pattern: Pattern 4	0.2	0.6	3.3	-0.1	-0.5	-0.4	-0.9	-0.7	-0.9	-0.6	-0.4	-0.2	-0.5	-1.1	-0.1	-0.1	-0.9	1.8	1.8	0.1	-0.1	-0.6	-0.1	1.0	-0.3
Number of full brothers	0.2	0.3	1.3	0.4	-0.4	-0.5	0.1	-0.1	0.0	-0.1	-0.4	-0.6	-0.3	0.4	-0.3	-0.3	-0.1	0.5	0.4	-0.8	-0.8	-0.9	-0.9	-1.1	-0.7
Number of full sisters	0.2	0.3	0.8	-0.7	-0.7	-0.4	-0.4	-0.0	-0.3	-0.5	-0.2	-0.6	-0.2	-0.7	0.9	0.5	-0.6	-0.8	0.0	-0.7	0.2	-0.7	-0.6	0.0	-0.6
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.2	1.2	-0.5	0.1	-0.9	-0.9	0.3	0.1	0.0	-0.2	-0.0	-0.1	0.3	0.2	0.2	0.0	0.3	0.2	0.1	-0.4	0.2	-0.9	1.1	-0.9
Illness, injury, bereavement, stress in last 2 years	0.2	0.3	1.6	0.5	-0.2	0.6	-0.1	0.5	0.7	0.2	0.4	0.2	-0.3	1.3	0.5	0.6	0.5	0.1	0.4	0.2	0.5	0.4	0.8	0.1	0.5
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.5	2.2	-0.9	0.4	-0.6	-0.6	1.0	1.0	0.1	0.8	0.2	0.3	0.8	1.5	1.2	0.8	-0.2	0.1	0.3	0.4	0.5	-0.4	0.6	-0.5
Medication for cholesterol	0.2	0.3	1.4	-0.9	0.1	-0.6	-0.2	0.6	0.8	-0.0	-0.6	-1.2	-0.3	0.2	-0.4	-0.0	0.5	-0.6	0.1	-0.4	-0.4	-1.1	-0.7	-0.2	-0.5
Ever smoked	0.2	0.4	3.5	-0.1	0.3	-0.3	-0.2	0.4	0.1	-0.1	0.5	-0.2	-0.1	0.0	1.0	0.9	0.1	1.3	1.1	0.4	0.4	-0.1	-0.3	1.9	-0.3
Alcohol drinker status: Previous	0.2	0.2	0.9	0.6	-0.4	0.5	0.7	-0.4	-0.5	0.4	-0.1	0.1	-0.0	-1.0	0.4	0.1	-0.7	0.3	0.7	0.3	0.6	-0.4	0.4	-0.0	0.5
Frequency of depressed mood in last 2 weeks	0.1	0.1	0.3	0.3	0.2	0.2	0.3	-0.4	-0.6	0.2	0.2	0.5	0.3	0.1	-0.2	-0.2	-0.2	-0.2	0.0	0.1	0.1	-0.4	0.2	-0.5	0.2
Reason for reducing amount of alcohol drunk: Health precaution	0.1	0.1	0.8	-0.7	-0.3	-0.1	-0.6	-0.4	-0.1	-0.3	-0.0	0.3	-0.2	0.2	-0.3	-0.3	-0.2	-0.9	-0.4	-0.1	-0.1	0.4	0.1	-0.5	-0.1
Handedness (chirality/laterality): Left-handed	0.1	0.2	1.9	0.5	-0.2	0.2	0.3	-0.3	-0.4	0.0	-0.1	0.5	-0.3	0.4	-0.3	-0.4	-0.0	-0.1	-1.4	-0.5	-0.3	0.1	0.2	-0.5	0.2

Hub : Genes

ENTPD6

Models

Trait associations