[Hub]/) : Traits : Arm predicted mass (right) :

chr2:168,949,234-170,419,444

Best TWAS P=7.97e-17 · Best GWAS P=4.54e-15 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex NOSTRIN 0.14 0.13 lasso 4 0.12 1.9e-14 -7.8 8.3 8.0e-17 -0.97 0.00 1.00 TRUE
2 GTEx Adrenal Gland NOSTRIN 0.21 0.09 lasso 4 0.09 4.1e-04 5.8 5.9 4.5e-09 -0.40 0.49 0.10 FALSE
3 GTEx Lung NOSTRIN 0.09 0.06 lasso 4 0.07 7.1e-06 6.8 6.2 4.6e-10 -0.39 0.46 0.41 FALSE
4 GTEx Pancreas NOSTRIN 0.30 0.12 enet 17 0.08 3.3e-04 -5.5 5.5 3.3e-08 -0.47 0.30 0.59 FALSE
5 GTEx Stomach NOSTRIN 0.15 0.04 enet 9 0.09 6.8e-05 6.8 7.2 6.8e-13 -0.58 0.40 0.49 FALSE
6 GTEx Testis NOSTRIN 0.43 0.17 enet 17 0.32 1.0e-14 -4.9 6.4 1.7e-10 -0.68 0.08 0.92 FALSE
7 METSIM Adipose NOSTRIN 0.07 0.09 lasso 6 0.08 1.6e-12 6.8 6.8 1.2e-11 -0.59 0.76 0.24 FALSE
8 The Cancer Genome Atlas Breast Invasive Carcinoma NOSTRIN 0.03 0.01 blup 55 0.02 9.5e-05 -5.4 6.1 1.3e-09 -0.37 0.02 0.96 FALSE
9 The Cancer Genome Atlas Colon Adenocarcinoma G6PC2 0.32 0.07 blup 29 0.06 3.8e-04 -5.6 -6.9 4.1e-12 0.79 0.00 0.96 FALSE
10 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma G6PC2 0.47 0.23 enet 8 0.28 4.4e-32 -5.6 -6.4 1.3e-10 0.79 0.00 1.00 FALSE
11 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma NOSTRIN 0.12 0.13 lasso 7 0.14 4.5e-15 -5.4 6.3 3.1e-10 -0.43 0.02 0.98 FALSE
12 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma G6PC2 0.56 0.13 blup 29 0.16 2.1e-09 -5.6 -6.6 3.5e-11 0.75 0.00 1.00 FALSE
13 The Cancer Genome Atlas Brain Lower Grade Glioma NOSTRIN 0.08 0.01 enet 6 0.04 2.1e-05 5.5 6.2 4.5e-10 -0.32 0.01 0.97 FALSE
14 The Cancer Genome Atlas Lung Squamous Cell Carcinoma NOSTRIN 0.05 0.00 blup 55 0.01 1.1e-02 -5.4 6.1 1.3e-09 -0.38 0.01 0.69 FALSE
15 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma NOSTRIN 0.17 0.07 lasso 2 0.08 4.3e-04 5.2 5.6 2.2e-08 -0.44 0.01 0.94 FALSE
16 The Cancer Genome Atlas Stomach Adenocarcinoma G6PC2 0.22 0.01 enet 4 0.08 3.1e-06 -5.6 -5.4 6.1e-08 0.71 0.00 0.96 FALSE
17 The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma NOSTRIN 0.27 0.04 lasso 3 0.08 2.8e-03 5.7 5.2 1.6e-07 -0.44 0.01 0.53 FALSE