[Hub]/) : Traits : Arm predicted mass (right) : ← →

chr1:22,648,411-24,216,118

Best TWAS P=3.85e-11 · Best GWAS P=2.41e-11 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex HTR1D 0.11 0.07 enet 21 0.09 1.1e-10 -5.3 5.9 2.8e-09 -0.78 0.25 0.75 FALSE
2 GTEx Brain Cortex LUZP1 0.23 0.14 lasso 5 0.10 7.8e-04 -6.6 6.6 4.5e-11 -1.00 0.02 0.82 FALSE
3 GTEx Cells Transformed fibroblasts LUZP1 0.09 0.09 lasso 4 0.08 2.8e-06 -6.6 6.6 3.9e-11 -1.00 0.01 0.99 TRUE
4 GTEx Esophagus Muscularis RP1-184J9.2 0.07 0.08 enet 6 0.05 6.1e-04 -5.3 5.1 2.8e-07 -0.72 0.32 0.56 FALSE
5 GTEx Testis LUZP1 0.17 0.09 lasso 4 0.08 2.6e-04 -5.7 -5.8 6.6e-09 0.55 0.20 0.31 FALSE
6 The Cancer Genome Atlas Colon Adenocarcinoma HTR1D 0.10 0.07 enet 7 0.08 3.8e-05 -6.1 6.6 5.4e-11 -0.94 0.01 0.98 FALSE
7 The Cancer Genome Atlas Pancreatic Adenocarcinoma HTR1D 0.24 0.12 lasso 4 0.12 1.2e-05 -5.8 6.4 1.9e-10 -0.76 0.07 0.90 FALSE
8 The Cancer Genome Atlas Rectum Adenocarcinoma HTR1D 0.19 0.12 enet 11 0.13 7.3e-04 -6.7 6.1 8.1e-10 -0.94 0.01 0.90 FALSE