Best TWAS P=3.28e-09 · Best GWAS P=7.85e-10 conditioned to 0.0567
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Coronary | CTNNB1 | 0.30 | 0.00 | lasso | 4 | 0.01 | 1.0e-01 | 6.0 | -5.7 | 1.4e-08 | -0.93 | 0.03 | 0.55 | FALSE |
| 2 | GTEx | Nerve Tibial | CTNNB1 | 0.05 | 0.00 | enet | 4 | 0.00 | 2.0e-01 | 4.9 | 5.1 | 3.1e-07 | 0.69 | 0.07 | 0.55 | FALSE |
| 3 | NTR | Blood | CTNNB1 | 0.04 | 0.04 | lasso | 6 | 0.04 | 4.6e-13 | 5.8 | -5.9 | 3.3e-09 | -0.89 | 0.02 | 0.98 | TRUE |