[Hub]/) : Traits : Arm predicted mass (right) : ← →

chr3:183,204,923-184,724,719

Best TWAS P=5.2e-20 · Best GWAS P=5.47e-22 conditioned to 0.000736

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex ECE2 0.24 0.20 bslmm 542 0.19 1.6e-22 7.1 6.9 7.1e-12 -0.37 1.00 0.00 FALSE
2 GTEx Artery Tibial PSMD2 0.13 0.09 lasso 5 0.08 1.3e-06 -5.6 5.8 5.1e-09 -0.42 0.88 0.02 FALSE
3 GTEx Brain Putamen basal ganglia ECE2 0.38 0.03 enet 22 0.11 1.4e-03 7.2 5.9 4.0e-09 -0.28 0.08 0.16 FALSE
4 GTEx Pituitary ECE2 0.52 0.30 lasso 7 0.23 1.5e-06 7.2 6.2 4.9e-10 -0.31 0.39 0.23 FALSE
5 GTEx Skin Sun Exposed Lower leg ABCF3 0.13 0.08 lasso 4 0.11 1.6e-09 5.1 6.1 1.1e-09 -0.36 0.98 0.01 FALSE
6 GTEx Skin Sun Exposed Lower leg PSMD2 0.13 0.14 lasso 4 0.15 1.4e-12 -5.6 5.8 6.1e-09 -0.39 1.00 0.00 FALSE
7 YFS Blood PSMD2 0.26 0.22 lasso 5 0.24 2.4e-77 -5.6 5.2 1.5e-07 -0.39 1.00 0.00 FALSE
8 The Cancer Genome Atlas Breast Invasive Carcinoma PSMD2 0.03 0.03 blup 50 0.03 4.8e-06 -5.6 5.5 4.9e-08 -0.48 0.66 0.27 FALSE
9 The Cancer Genome Atlas Brain Lower Grade Glioma ECE2 0.04 0.02 blup 61 0.03 3.5e-04 7.2 6.7 2.6e-11 -0.24 0.54 0.02 FALSE
10 The Cancer Genome Atlas Lung Adenocarcinoma PSMD2 0.09 0.02 blup 50 0.05 1.2e-06 -8.6 9.2 5.2e-20 -0.73 0.03 0.84 TRUE
11 The Cancer Genome Atlas Lung Squamous Cell Carcinoma PSMD2 0.05 0.00 enet 10 0.01 3.6e-02 7.1 6.2 6.6e-10 -0.49 0.01 0.10 FALSE
12 The Cancer Genome Atlas Testicular Germ Cell Tumors VWA5B2 0.10 0.04 blup 51 0.04 1.8e-02 5.1 -7.4 1.1e-13 0.43 0.03 0.33 TRUE