Best TWAS P=1.74e-10 · Best GWAS P=9.96e-13 conditioned to 0.000767
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Breast Invasive Carcinoma | IBSP | 0.05 | 0.05 | lasso | 6 | 0.07 | 1.2e-13 | -7.1 | 6.4 | 2.0e-10 | -0.89 | 0.00 | 1.00 | FALSE |
| 2 | The Cancer Genome Atlas | Colon Adenocarcinoma | IBSP | 0.09 | 0.02 | enet | 15 | 0.07 | 9.4e-05 | -1.9 | 5.5 | 4.0e-08 | -0.71 | 0.02 | 0.62 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | IBSP | 0.08 | 0.00 | blup | 77 | 0.00 | 1.6e-01 | -5.1 | 6.4 | 1.7e-10 | -0.80 | 0.02 | 0.63 | TRUE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | IBSP | 0.06 | 0.01 | blup | 78 | 0.03 | 8.2e-05 | -5.2 | 5.5 | 4.8e-08 | -0.61 | 0.02 | 0.87 | FALSE |
| 5 | The Cancer Genome Atlas | Lung Adenocarcinoma | IBSP | 0.06 | 0.01 | blup | 78 | 0.03 | 7.7e-05 | -7.1 | 6.2 | 6.6e-10 | -0.84 | 0.00 | 0.99 | FALSE |
| 6 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | IBSP | 0.16 | 0.05 | blup | 76 | 0.08 | 3.6e-06 | 4.6 | 5.1 | 3.0e-07 | -0.65 | 0.27 | 0.72 | FALSE |