[Hub]/) : Traits : Arm predicted mass (right) : ← →

chr4:105,598,022-107,092,169

Best TWAS P=1.41e-17 · Best GWAS P=2.32e-19 conditioned to 0.000416

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex PPA2 0.08 0.03 bslmm 429 0.04 2.2e-05 -5.3 -6.2 6.8e-10 0.61 0.08 0.89 FALSE
2 GTEx Artery Aorta PPA2 0.11 -0.01 enet 24 0.01 1.6e-01 -8.5 -6.2 4.8e-10 0.58 0.07 0.36 FALSE
3 GTEx Brain Cortex PPA2 0.14 0.09 lasso 9 0.09 1.6e-03 -7.0 -7.1 1.0e-12 0.79 0.08 0.46 FALSE
4 GTEx Cells Transformed fibroblasts PPA2 0.11 0.03 lasso 3 0.01 6.5e-02 -5.9 -6.2 4.2e-10 0.59 0.42 0.10 FALSE
5 GTEx Esophagus Gastroesophageal Junction PPA2 0.29 0.15 lasso 5 0.14 8.8e-06 -8.5 -8.5 1.4e-17 0.81 0.08 0.87 TRUE
6 GTEx Esophagus Mucosa PPA2 0.18 0.06 enet 14 0.12 2.5e-08 6.6 -7.2 8.3e-13 0.68 0.10 0.90 FALSE
7 GTEx Heart Atrial Appendage PPA2 0.15 0.05 lasso 7 0.06 7.4e-04 -7.3 -5.7 1.3e-08 0.70 0.24 0.37 FALSE
8 GTEx Muscle Skeletal PPA2 0.19 0.06 enet 28 0.11 8.7e-11 -7.1 -5.2 2.1e-07 0.67 0.76 0.24 FALSE
9 GTEx Nerve Tibial PPA2 0.13 0.07 enet 23 0.07 2.1e-05 -5.9 -5.9 3.8e-09 0.63 0.54 0.19 FALSE
10 GTEx Ovary PPA2 0.18 0.10 lasso 3 0.14 2.2e-04 -5.9 -6.9 4.1e-12 0.72 0.08 0.59 FALSE
11 The Cancer Genome Atlas Thyroid Carcinoma PPA2 0.04 0.02 blup 84 0.04 6.1e-05 -7.1 -6.5 8.1e-11 0.74 0.14 0.66 FALSE