Best TWAS P=6.68e-08 · Best GWAS P=1.41e-10 conditioned to 0.000181
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Nerve Tibial | MAPK9 | 0.13 | 0.06 | lasso | 5 | 0.05 | 1.7e-04 | 3.2 | 5.1 | 2.7e-07 | -0.86 | 0.01 | 0.99 | FALSE |
| 2 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | MAPK9 | 0.07 | 0.00 | blup | 96 | 0.02 | 8.4e-04 | 2.6 | 5.3 | 1.5e-07 | -0.66 | 0.02 | 0.54 | FALSE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | MAPK9 | 0.06 | 0.04 | lasso | 3 | 0.05 | 2.9e-05 | 5.8 | 5.4 | 6.7e-08 | -0.68 | 0.04 | 0.92 | TRUE |