TWAS hub - MAPK9

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.1100	0.0430	3.3e-03	0.069	NA	0.021	NA	0.045	2.5e-06	NA	7.6e-03	NA	1.3e-04
2	GTEx	Adipose Visceral Omentum	0.2400	0.0670	1.0e-04	0.103	NA	0.087	NA	0.106	5.4e-06	NA	2.8e-05	NA	4.1e-06
3	GTEx	Artery Tibial	0.1892	0.0398	7.1e-09	0.101	NA	0.142	NA	0.136	2.8e-08	NA	3.0e-11	NA	8.6e-11
4	GTEx	Brain Cerebellar Hemisphere	0.3410	0.1040	1.2e-03	0.035	NA	0.141	NA	0.129	4.5e-02	NA	1.8e-04	NA	3.5e-04
5	GTEx	Brain Nucleus accumbens basal ganglia	0.6060	0.1240	5.3e-03	-0.003	NA	0.230	NA	0.148	4.0e-01	NA	7.8e-07	NA	9.1e-05
6	GTEx	Lung	0.0962	0.0364	3.7e-03	0.049	NA	0.027	NA	0.045	1.3e-04	NA	3.8e-03	NA	2.2e-04
7	GTEx	Nerve Tibial	0.1335	0.0426	8.5e-04	0.057	NA	0.033	NA	0.051	6.7e-05	NA	2.0e-03	NA	1.7e-04
8	GTEx	Pancreas	0.1360	0.0560	9.5e-03	0.127	NA	0.106	NA	0.100	5.2e-06	NA	3.3e-05	NA	5.3e-05
9	GTEx	Skin Not Sun Exposed Suprapubic	0.2060	0.0610	8.2e-05	0.066	NA	0.036	NA	0.051	1.7e-04	NA	4.4e-03	NA	8.5e-04
10	GTEx	Skin Sun Exposed Lower leg	0.1100	0.0330	6.9e-05	0.075	NA	0.096	NA	0.078	8.6e-07	NA	2.6e-08	NA	4.9e-07
11	GTEx	Testis	0.2090	0.0710	2.4e-03	0.063	NA	0.097	NA	0.097	9.1e-04	NA	4.6e-05	NA	4.4e-05
12	GTEx	Thyroid	0.1440	0.0460	9.4e-05	0.064	NA	0.058	NA	0.058	1.2e-05	NA	3.2e-05	NA	3.1e-05
13	NTR	Blood	0.0232	0.0080	1.7e-04	0.015	0.018	0.013	0.019	0.017	9.9e-06	9.4e-07	3.9e-05	8.4e-07	1.7e-06
14	ROSMAP	Brain Pre-frontal Cortex	0.1094	0.0257	1.3e-08	0.047	0.061	0.052	0.056	0.039	1.0e-06	2.3e-08	2.7e-07	1.0e-07	8.2e-06
15	YFS	Blood	0.0870	0.0186	4.0e-13	0.031	0.049	0.049	0.051	0.056	1.7e-10	1.5e-15	7.7e-16	2.0e-16	9.2e-18
16	TCGA	Colon Adenocarcinoma	0.0790	0.0400	4.5e-03	0.019	0.027	0.022	NA	0.029	2.6e-02	1.1e-02	1.9e-02	NA	8.4e-03
17	TCGA	Kidney Renal Clear Cell Carcinoma	0.0724	0.0411	1.0e-03	-0.002	0.024	0.011	NA	0.001	6.7e-01	8.4e-04	1.7e-02	NA	2.5e-01
18	TCGA	Thyroid Carcinoma	0.0590	0.0250	2.2e-04	0.042	0.045	0.036	NA	0.045	5.7e-05	3.0e-05	1.8e-04	NA	2.9e-05

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18
Forced expiratory volume in 1-second (FEV1), predicted	5.3	11.1	30.1	3.4	3.5	3.7	1.9	1.6	3.9	5.5	0.1	4.0	3.1	0.8	3.4	2.3	1.0	3.1	3.5	4.4	5.1
Migraine (self-reported)	4.7	5.9	10.9	2.2	1.8	2.7	2.2	-2.1	2.7	2.7	3.1	2.7	2.6	3.3	2.9	2.6	-1.1	-0.9	2.0	2.9	1.6
Standing height	3.8	37.5	109.2	5.4	6.3	5.4	5.5	-1.0	7.1	10.4	0.8	6.7	6.1	3.5	6.4	4.9	0.4	4.0	5.8	9.3	9.5
Headache pain in last month	3.8	6.5	15.6	3.2	1.7	2.5	1.9	-0.4	2.9	2.3	4.0	3.3	3.0	3.4	3.4	2.7	-2.6	-1.2	1.2	2.0	-0.1
Comparative height size at age 10	3.8	20.9	56.1	4.3	3.7	4.2	3.9	-1.0	5.3	7.5	1.0	5.2	4.8	2.1	4.9	4.4	0.7	3.1	4.6	6.7	7.1
Ever depressed for a whole week	3.4	4.2	9.4	-2.8	-2.6	-3.1	-2.4	-1.6	-2.1	-2.0	-0.8	-2.6	-2.4	-0.9	-2.2	-1.5	0.6	-1.2	-2.5	-1.5	-1.7
Height	2.9	55.2	178.2	6.8	6.8	6.0	6.2	-1.8	8.8	13.4	1.6	8.5	7.5	4.8	8.0	6.2	0.4	4.4	6.6	10.9	11.4
Forced vital capacity (FVC)	2.8	10.9	25.0	2.6	4.1	3.7	2.9	1.4	4.0	5.0	1.2	3.5	3.6	1.9	3.3	2.8	-1.5	1.6	4.1	3.7	4.8
Noisy workplace	2.8	3.5	6.8	2.0	2.1	2.4	1.0	-0.9	2.5	2.2	2.1	2.6	2.4	1.7	2.6	1.6	-0.6	0.3	1.8	1.7	0.6
Osteoarthritis (self-reported)	2.6	3.4	8.5	-2.9	-1.9	-2.9	0.4	-1.1	-2.3	-1.6	-2.3	-2.5	-2.2	-0.5	-2.5	-2.2	0.9	-1.1	-1.4	0.4	0.3
Medication: Gliclazide	2.6	3.0	7.4	2.0	1.6	1.5	1.4	-0.6	2.0	1.5	1.7	2.1	2.2	1.5	2.0	2.7	-0.5	-0.1	2.0	1.8	1.5
Ever unenthusiastic/disinterested for a whole week	2.5	3.1	7.2	-2.3	-1.7	-2.7	-2.0	-0.8	-2.5	-2.0	-0.7	-2.6	-2.1	-0.5	-2.2	-1.2	0.7	-1.4	-1.9	-1.0	-0.4
Forced vital capacity (FVC), Best measure	2.5	9.1	24.1	2.7	3.2	3.1	3.0	1.7	3.8	4.9	0.6	3.4	3.2	1.4	3.1	2.6	-0.9	2.0	3.2	3.6	4.2
Comparative body size at age 10	2.5	6.8	13.8	-2.4	-2.8	-2.8	-2.1	-1.0	-3.7	-3.6	-2.6	-3.4	-3.3	-2.2	-3.3	-2.7	1.6	0.2	-2.2	-2.7	-1.3
Medication: Ibuprofen (e.g. Nurofen)	2.4	3.0	7.9	1.9	1.7	1.3	2.5	-0.4	0.9	0.7	2.6	1.6	2.0	2.0	2.0	1.7	-2.8	-0.1	1.2	2.2	0.4
Lung cancer (father)	2.4	2.8	9.1	1.0	2.4	1.2	1.2	-1.0	1.7	1.9	0.3	1.7	2.0	0.8	1.6	1.8	-0.5	1.0	2.2	3.0	2.2
Pain experienced in last month	2.4	4.0	11.2	-2.3	-0.6	-0.6	-1.6	1.5	-2.3	-2.1	-2.6	-2.6	-2.2	-3.4	-2.8	-1.8	2.4	1.4	-0.3	-1.3	0.8
Frequency of tenseness / restlessness in last 2 weeks	2.3	3.6	6.5	2.1	2.6	1.4	2.1	0.5	2.5	2.3	1.6	2.3	2.4	1.8	2.3	1.8	-1.5	0.1	2.0	1.6	1.0
Trunk fat-free mass	2.3	13.1	34.9	3.6	2.4	3.4	2.1	-0.2	3.7	5.9	0.0	4.3	3.3	0.9	3.7	3.0	1.6	4.4	3.2	5.8	5.9
Forced expiratory volume in 1-second (FEV1)	2.3	7.8	20.8	2.0	3.3	3.1	2.2	1.3	3.5	4.6	0.5	3.0	3.0	0.4	2.8	1.9	-0.9	2.7	3.4	3.2	4.2
Forced expiratory volume in 1-second (FEV1), Best measure	2.3	7.3	20.7	2.1	2.9	2.7	2.2	1.4	3.3	4.5	0.1	2.8	2.7	0.0	2.6	1.9	-0.4	3.1	3.0	3.5	4.1
Trunk predicted mass	2.3	13.0	34.8	3.6	2.4	3.3	2.1	-0.2	3.7	5.9	0.0	4.3	3.2	0.9	3.7	3.0	1.5	4.4	3.1	5.8	5.8
Glaucoma (self-reported)	2.3	2.7	5.8	-2.0	-1.6	-2.4	0.2	-0.1	-1.7	-2.0	-1.4	-2.2	-1.6	-1.6	-1.9	-1.3	0.3	-0.5	-1.6	-2.3	-1.9
Illnesses of father: Heart disease	2.3	3.1	6.4	-1.3	-2.0	-1.5	-2.4	-0.8	-2.1	-1.9	-1.3	-2.0	-2.5	-1.3	-2.2	-1.4	2.3	0.2	-1.6	-2.4	-0.6
Heart disease (siblings)	2.3	2.9	5.0	-1.2	-2.2	-1.7	-1.1	0.1	-1.7	-1.5	-1.9	-1.7	-1.9	-2.2	-1.7	-1.7	1.8	1.0	-1.9	-1.9	-1.7
Neuroticism (2016)	2.2	3.2	6.1	2.0	2.5	1.7	1.3	-0.7	2.2	2.0	1.6	2.0	2.3	1.9	2.2	2.3	-1.4	0.3	1.8	1.4	0.3
Medication: Ibuprofen	2.2	2.6	6.1	1.6	1.7	1.3	2.3	-0.3	0.9	0.6	2.5	1.3	1.8	1.6	1.7	1.9	-2.4	-0.4	1.5	2.1	0.6
Age at First Birth	2.1	3.0	8.0	-1.9	-1.3	-1.7	-1.8	1.0	-2.6	-2.2	-0.2	-2.4	-2.1	-0.2	-2.5	-0.5	1.0	-1.8	-1.1	-2.8	-0.2
Arm fat-free mass (right)	2.1	10.9	29.8	3.3	2.0	3.0	1.9	-1.0	3.4	5.3	0.4	3.8	3.1	1.1	3.5	3.0	1.4	3.8	2.9	5.5	5.3
Ever had prostate specific antigen (PSA) test	2.1	2.4	4.6	-2.1	-1.2	-2.2	-0.4	1.3	-2.1	-1.5	-1.9	-2.0	-1.9	-0.9	-2.0	-2.0	0.3	-0.3	-1.6	-1.0	-0.9
Multivitamins +/- minerals	2.0	2.5	8.7	1.6	2.1	1.5	0.7	-0.9	1.4	0.8	1.5	1.8	2.0	1.9	1.9	1.6	-3.0	-0.4	1.6	1.4	0.2
Arm predicted mass (right)	2.0	10.2	29.2	3.2	2.0	2.9	1.7	-0.7	3.2	5.1	0.5	3.7	2.9	1.2	3.2	2.9	1.3	3.6	2.8	5.3	5.4
Eye problems/disorders: Glaucoma	2.0	2.4	5.1	-2.2	-1.5	-2.2	0.2	0.5	-1.7	-1.9	-1.4	-2.3	-1.5	-1.0	-2.1	-1.1	-0.1	-1.0	-1.5	-1.7	-1.2
Number of operations (self-reported)	2.0	3.0	6.6	2.2	2.0	1.3	1.7	0.5	2.0	2.0	0.0	2.3	2.1	0.3	2.2	1.5	-0.2	2.5	1.4	2.6	1.0
Qualifications: CSEs or equivalent	1.9	2.5	5.8	2.0	0.8	1.9	0.6	-0.6	1.8	1.7	1.3	2.0	1.9	0.8	2.0	2.1	1.3	0.9	1.4	2.4	0.8
Medication for pain relief, constipation, heartburn	1.9	3.2	10.6	-0.7	-0.6	-1.1	-2.4	1.1	-1.5	-1.5	-2.4	-1.3	-1.8	-3.3	-1.9	-1.6	2.1	2.3	-0.9	-2.4	-0.5
Medication: Lisinopril	1.9	2.4	6.8	1.3	1.3	1.4	-0.3	0.3	1.5	2.3	0.5	1.4	1.6	2.0	1.2	1.8	1.7	0.1	1.6	2.6	2.3
Sensitivity / hurt feelings	1.8	3.1	7.5	2.1	1.4	1.1	2.0	-0.8	2.1	2.6	0.7	2.4	2.1	0.7	2.4	1.3	-1.8	1.4	0.7	2.7	0.7
Medication: Co-codamol	1.8	2.0	5.1	1.7	0.6	1.2	0.7	-0.2	1.6	2.1	1.6	1.9	1.7	2.3	2.0	1.2	-0.4	-0.2	0.7	2.0	0.5
Neuroticism score	1.8	3.8	9.7	2.6	1.3	1.0	1.6	-1.9	2.4	3.1	1.5	2.6	2.2	1.7	2.7	2.3	-1.1	0.3	0.7	2.4	0.8
Arm fat-free mass (left)	1.8	8.9	27.2	3.1	1.7	2.5	1.5	-0.8	2.8	4.7	0.6	3.5	2.7	1.2	3.1	3.0	1.3	3.4	2.5	5.2	4.8
Alcohol drinker status: Previous	1.8	2.1	6.8	1.6	0.7	1.2	2.6	1.0	1.9	1.3	1.1	1.8	1.7	1.5	1.8	2.3	-0.4	-0.6	1.0	0.2	-0.4
Neuroticism (Nagel 2018)	1.7	4.0	7.6	2.8	1.5	0.7	2.7	0.1	2.4	2.4	1.9	2.7	2.3	1.7	2.7	2.7	-2.0	0.1	0.6	2.2	0.1
Waist Hip Ratio (WHR)	1.7	7.7	19.9	1.8	2.6	2.7	2.3	0.3	3.2	1.9	4.5	2.5	3.4	3.3	2.9	4.4	-1.8	-2.9	3.3	1.5	1.0
Pulse wave reflection index	1.7	2.2	7.7	-0.9	-0.1	-0.9	-1.8	-1.7	-1.4	-0.8	-2.5	-1.6	-1.8	-0.9	-1.8	-1.2	2.8	0.9	-0.5	0.7	1.4
Ever highly irritable/argumentative for 2 days	1.7	2.0	4.8	-1.4	-1.2	-1.7	-1.2	-0.2	-1.7	-1.8	-0.0	-1.9	-1.8	-0.2	-1.8	-0.3	-0.0	-2.2	-1.3	-2.0	-1.1
Number of children fathered	1.7	1.9	5.8	1.3	2.4	1.6	0.9	1.0	1.2	1.3	1.1	1.3	1.5	1.7	1.1	1.3	1.1	-0.3	1.8	1.5	1.2
Mouth/teeth dental problems: Loose teeth	1.7	2.0	7.8	-1.5	-0.9	-0.9	-1.0	0.9	-2.0	-2.4	0.3	-2.1	-1.3	0.3	-1.8	0.0	0.3	-2.8	-0.3	-1.6	-0.7
Whole body fat-free mass	1.7	9.7	25.8	3.0	1.7	2.7	1.9	-0.8	3.1	5.1	-0.1	3.6	2.7	0.6	3.2	2.7	1.6	4.1	2.6	5.1	5.1
Whole body water mass	1.7	9.7	25.8	3.0	1.7	2.7	1.9	-0.8	3.0	5.0	-0.1	3.6	2.7	0.6	3.2	2.7	1.6	4.2	2.7	5.1	5.1
Basal metabolic rate	1.7	9.2	25.4	3.1	1.7	2.7	1.9	-1.1	3.0	4.7	0.3	3.5	2.8	0.8	3.2	3.0	1.2	3.8	2.7	5.0	4.6
Number of treatments/medications taken	1.6	2.8	7.0	1.0	0.3	0.4	2.5	-0.4	1.4	0.5	2.6	1.3	1.9	2.4	1.8	2.4	-2.2	-2.2	0.6	1.5	-1.1
Hand grip strength (right)	1.6	4.2	16.0	1.4	3.0	1.8	1.2	-0.6	2.1	3.9	-0.3	1.7	1.3	0.3	1.3	0.6	1.3	2.4	2.1	2.6	4.0
Average weekly fortified wine intake	1.6	1.9	4.1	-1.7	0.4	-0.4	-2.0	-0.9	-1.8	-0.9	-1.3	-1.7	-1.8	0.0	-2.0	-1.8	1.5	-1.1	-0.2	0.2	1.7
Hearing difficulty/problems with background noise	1.6	2.5	8.7	1.4	1.5	0.7	2.9	1.2	1.2	1.0	2.0	1.3	1.8	1.4	1.5	2.8	-1.3	-1.1	1.4	1.1	0.4
Medication: Paracetamol	1.6	2.6	5.9	1.1	0.5	1.7	1.4	0.3	2.4	1.9	1.6	1.8	2.1	1.9	2.4	1.5	-1.3	-0.8	1.3	2.2	0.3
Number of full sisters	1.6	1.9	8.1	-1.5	-0.4	-1.2	-2.3	-2.2	-0.6	0.2	-1.7	-0.9	-1.0	-1.5	-1.0	-1.3	2.8	1.0	-0.4	0.1	0.7
Leg pain on walking	1.6	2.0	9.7	0.4	1.1	0.5	-0.2	-1.1	0.4	-0.2	2.6	0.4	0.8	3.0	0.6	1.9	-1.1	-3.1	0.8	0.4	0.0
Arm predicted mass (left)	1.6	8.3	23.8	3.0	1.5	2.3	1.7	-0.8	2.7	4.5	0.4	3.4	2.6	0.9	3.0	2.9	1.4	3.5	2.3	4.9	4.7
Number of incorrect matches in round	1.5	2.4	7.0	-1.9	-1.2	-1.4	-0.5	1.0	-2.3	-2.4	0.0	-2.4	-1.8	0.2	-2.2	-0.8	-0.8	-2.6	-0.9	-1.1	-0.7
Medication: Paracetamol	1.5	2.3	6.0	0.7	0.7	1.6	1.4	0.0	1.7	1.4	1.7	1.2	1.7	2.5	1.8	1.3	-1.3	-1.9	1.5	2.1	0.6
Cholesterol lowering medication	1.5	2.2	9.4	-1.2	-1.2	-2.2	-2.1	-1.0	-0.5	-0.2	-2.3	-0.9	-1.1	-1.3	-1.1	-0.4	3.1	0.9	-1.2	-1.7	-0.8
Worry (Nagel 2018)	1.4	3.0	6.3	2.3	1.0	0.6	1.8	-2.0	2.3	2.5	1.1	2.3	1.8	1.6	2.3	2.1	-1.6	-0.4	0.4	1.9	0.2
Neuroticism	1.4	3.4	7.6	2.6	1.2	0.7	1.6	-0.9	2.2	2.7	1.3	2.6	2.2	1.1	2.6	2.5	-1.2	0.5	0.7	2.5	0.6
Vitamin and mineral supplements	1.4	1.9	3.6	-1.5	-1.2	-1.6	-0.9	1.1	-1.5	-1.2	-1.1	-1.7	-1.7	-1.5	-1.7	-1.4	1.9	-0.0	-1.2	-1.4	-0.3
Blood clot in the leg (DVT)	1.4	1.8	6.9	1.8	0.6	1.1	1.9	1.0	1.1	0.4	1.3	1.7	1.6	1.0	1.5	1.8	-2.6	0.2	0.7	0.7	-0.5
Pain type(s) experienced in last month: Hip pain	1.4	1.8	3.8	1.1	1.0	0.4	1.5	-1.9	1.6	1.9	1.0	1.3	1.5	2.0	1.6	1.6	-0.4	-1.0	0.9	1.1	0.8
Deep venous thrombosis (DVT) (self-reported)	1.4	1.8	6.9	1.8	0.7	1.2	1.8	0.9	1.0	0.4	1.3	1.6	1.5	0.9	1.4	1.9	-2.6	0.3	0.9	0.5	-0.3
Ever had hysterectomy (womb removed)	1.3	1.5	5.8	-1.3	-0.6	-1.1	-0.3	0.2	-2.2	-2.4	-0.6	-2.0	-1.1	-1.2	-1.7	0.3	1.2	0.0	-0.6	0.1	-0.4
Allergy	1.3	3.0	6.9	1.5	2.5	2.0	0.8	-0.3	1.9	2.2	1.2	1.8	1.5	2.3	1.7	1.6	0.3	-1.1	1.7	2.6	1.7
Hayfever/allergic rhinitis (self-reported)	1.3	1.8	6.8	-0.7	-2.6	-1.2	-1.0	0.5	-1.0	-1.1	-0.8	-0.7	-1.1	-1.5	-0.7	-1.7	-0.9	0.6	-1.9	-1.4	-2.2
Back pain experienced in last month	1.3	1.9	6.3	1.3	0.2	0.7	0.6	-1.5	1.7	1.9	1.4	1.6	1.7	2.5	2.0	1.2	-0.8	-1.1	0.5	1.5	-0.1
Wears glasses or contact lenses	1.3	1.5	3.0	1.7	1.6	1.6	0.5	1.7	1.0	0.6	-0.1	1.6	1.2	0.3	1.1	0.8	-0.5	1.4	1.4	1.6	0.9
Coronary Artery Disease (CAD)	1.2	1.4	6.7	-0.1	-0.3	-1.0	0.2	2.6	-2.0	-2.0	-0.9	-1.3	-1.7	0.1	-1.5	-0.8	-0.5	-0.4	-0.3	-0.0	-0.5
Diabetes (father)	1.2	1.4	4.7	2.0	1.3	1.6	-0.9	-0.7	1.2	1.1	0.1	2.2	1.2	1.3	1.4	0.6	-0.7	1.0	0.9	0.8	0.3
Nervous feelings	1.2	2.2	7.9	1.7	1.0	0.5	1.6	-2.8	1.5	1.8	0.2	1.5	1.3	0.7	1.5	1.0	-1.7	0.5	0.4	2.7	0.7
Mouth/teeth dental problems	1.2	1.8	14.7	1.0	0.0	0.5	-0.2	0.6	0.7	0.2	-1.3	1.4	0.5	-2.1	1.0	-1.6	-0.5	3.8	-0.7	-0.7	-1.7
Weight	1.2	5.9	17.2	2.7	1.4	2.1	1.9	-1.4	2.4	3.0	1.0	2.9	2.5	1.2	2.8	3.1	0.4	2.3	2.3	4.2	3.0
Father’s age at death	1.2	1.6	4.7	-0.2	-0.3	-1.1	-1.1	0.0	-1.6	-1.3	-2.2	-1.1	-1.6	-1.9	-1.3	-2.0	0.6	1.5	-0.8	-0.5	-0.2
Depression (self-reported)	1.2	1.4	4.0	-1.5	-2.0	-1.6	0.6	0.3	-0.6	-0.5	-1.2	-1.4	-1.4	-1.2	-1.1	-1.5	0.8	0.6	-1.4	-0.9	-1.2
Neck or shoulder pain in last month	1.2	1.7	8.4	1.1	0.4	0.2	1.0	-2.9	1.0	1.1	1.9	1.1	1.7	1.4	1.4	1.5	-1.0	-0.0	0.0	1.4	-0.4
Suffer from ‘nerves’	1.2	1.8	4.0	1.8	0.8	0.3	1.9	-0.7	1.9	1.9	0.5	1.9	1.3	1.2	2.0	0.7	-2.0	0.8	0.1	0.8	-0.7
Mood swings	1.2	2.1	5.4	2.1	0.3	0.3	1.5	0.7	2.0	2.3	1.0	2.2	1.7	0.5	2.1	1.3	-1.0	1.7	0.2	1.5	0.2
Breast cancer (self-reported)	1.2	1.4	6.7	0.3	2.6	1.6	1.0	-0.2	0.7	0.1	0.8	0.4	1.7	0.6	0.8	0.9	-0.9	-0.4	2.1	1.3	1.2
Alzheimer’s Disease (in father)	1.1	1.2	4.7	-0.4	-0.3	-0.9	-2.2	-0.0	-1.7	-1.5	-0.8	-1.2	-1.1	-1.0	-1.4	-0.9	1.4	1.1	-0.8	-0.2	-0.2
Body Mass Index (BMI) (2010)	1.1	1.5	3.8	-0.9	-0.9	-0.6	-1.8	-0.1	-1.5	-1.2	-1.6	-1.4	-1.8	-1.6	-1.5	-0.8	2.0	0.2	-0.4	-0.5	0.5
Type 2 Diabetes (T2D) (2012)	1.1	1.2	4.8	1.2	2.2	1.4	0.2	0.5	0.7	0.9	0.8	0.7	0.8	1.5	0.5	1.1	-0.5	-0.8	1.5	1.0	1.8
Ulcerative Colitis	1.1	1.5	6.9	-0.6	1.5	-0.1	1.1	1.2	-0.1	-1.3	1.7	-0.4	0.8	1.1	0.1	1.6	-2.1	-2.6	1.4	0.2	-0.2
Pack years adult smoking proportion	1.1	1.6	5.0	0.8	1.1	2.1	1.0	0.1	1.7	1.1	1.0	1.2	1.6	1.5	1.2	1.3	0.0	-0.4	2.2	1.2	1.1
Impedance of leg (right)	1.1	5.3	15.1	1.2	3.4	1.2	2.5	-0.3	2.4	2.1	2.8	1.6	2.4	3.9	2.0	1.8	-2.9	-3.3	1.4	2.0	0.8
Current tobacco smoking	1.1	1.8	4.3	1.8	1.0	1.1	0.9	0.7	1.3	0.8	1.5	1.7	2.1	1.4	1.8	1.7	-0.8	0.1	0.8	1.9	-0.4
Diverticular disease/diverticulitis (self-reported)	1.1	1.3	3.2	0.7	1.3	1.3	0.7	-1.1	1.0	1.6	0.2	0.8	0.9	1.2	0.9	1.6	-0.4	-0.3	1.4	1.8	1.8
Impedance of leg (left)	1.1	5.5	15.1	1.3	3.4	1.4	2.3	-0.4	2.7	2.5	2.7	1.7	2.5	3.9	2.2	1.8	-2.7	-3.3	1.6	2.0	1.1
Heel bone mineral density (BMD) T-score, automated (right)	1.1	2.5	6.8	-1.1	-2.3	-1.8	-1.5	0.6	-1.0	-0.8	-1.3	-1.2	-1.7	-1.1	-1.2	-1.7	2.2	-0.0	-2.3	-2.6	-2.0
Frequency of tiredness / lethargy in last 2 weeks	1.1	1.8	4.2	1.6	-0.1	0.4	1.9	-0.8	1.6	1.7	1.4	1.8	1.9	1.3	2.0	1.2	-1.1	0.1	-0.1	1.6	-1.0
Length of working week for main job	1.1	1.2	3.5	-1.0	-1.2	-1.1	-0.3	-0.1	-1.8	-1.9	-0.3	-1.4	-1.6	-0.2	-1.4	-0.6	-0.4	-1.2	-1.2	-0.9	-1.1
Tense / ‘highly strung’	1.1	1.7	3.9	1.7	0.5	0.0	1.2	-2.0	1.7	1.5	1.3	1.6	1.3	1.6	1.8	1.3	-1.4	-0.6	-0.4	1.0	-1.2
Peak expiratory flow (PEF)	1.1	2.7	10.0	0.5	2.0	1.1	1.0	1.4	1.6	2.4	-0.7	1.2	1.3	-1.7	1.1	0.8	0.1	3.2	1.9	1.7	2.5
Medication for cholesterol, blood pressure or diabetes	1.1	1.8	5.6	-1.7	0.5	-0.7	-1.5	-0.6	0.1	0.9	-2.3	-0.9	-0.8	-2.2	-0.6	-1.7	2.4	1.5	-0.1	-1.4	0.5
Number of self-reported non-cancer illnesses	1.1	2.0	7.1	-1.6	-2.2	-2.7	1.0	-1.3	-1.3	-1.2	-0.7	-1.7	-1.1	-0.6	-1.1	-0.9	-0.0	-0.3	-2.2	0.3	-1.8
Irritability	1.1	1.8	5.1	0.9	-0.1	0.1	1.6	-0.7	1.1	1.2	2.3	1.2	1.4	2.1	1.5	1.5	-1.9	-2.0	-0.2	0.5	-0.6
Ovarian Cancer	1.0	1.3	5.1	-1.1	-0.7	-0.9	-0.5	0.7	-0.9	-0.1	-1.4	-1.1	-0.9	-2.1	-1.0	-0.8	1.8	2.3	-0.3	-0.3	0.7
Fed-up feelings	1.0	1.8	5.1	0.9	1.7	0.8	1.7	0.0	1.8	2.2	0.8	1.4	1.7	0.8	1.6	1.4	0.1	-0.1	1.6	1.5	1.3
Illnesses of siblings	1.0	1.4	3.2	1.2	1.3	1.4	1.8	0.2	1.5	1.3	0.4	1.6	1.3	0.8	1.5	1.0	-0.4	0.4	1.2	1.0	0.9
Shortness of breath walking on level ground	1.0	1.2	6.4	-1.1	-0.3	-1.1	-1.4	-0.9	-0.8	-1.1	1.5	-1.1	-0.5	1.0	-0.9	0.8	-1.1	-2.5	-0.6	-0.2	-0.3
Leg fat-free mass (right)	1.0	5.2	14.3	2.0	0.6	1.7	1.3	-1.4	2.1	3.6	-0.5	2.5	1.9	-0.3	2.2	2.1	1.6	3.8	1.8	3.5	3.7
Leg predicted mass (right)	1.0	5.3	15.1	2.0	0.7	1.7	1.3	-1.4	2.1	3.6	-0.5	2.5	1.9	-0.3	2.2	2.1	1.6	3.9	1.9	3.6	3.6
Ulcerative Colitis (UC)	0.9	1.7	4.2	0.4	2.0	1.3	0.6	0.3	0.5	-1.1	2.1	0.3	1.5	1.0	0.7	2.0	-1.9	-1.7	1.9	0.7	-0.4
Chronotype (morning person)	0.9	2.2	14.7	-0.9	-0.9	-0.1	-3.8	-1.0	-2.0	-1.7	0.0	-1.4	-1.7	0.2	-1.8	-0.5	1.3	-1.6	-0.4	-1.5	0.2
Severe depression (siblings)	0.9	1.0	7.5	1.2	0.6	0.6	-1.0	0.6	0.3	0.7	-1.0	0.7	0.4	-1.2	0.4	-0.7	1.0	2.7	0.2	0.7	0.8
Leg fat-free mass (left)	0.9	5.0	14.1	2.1	0.8	1.7	1.5	-1.4	2.0	3.4	-0.2	2.4	1.9	0.0	2.2	2.2	1.3	3.5	1.8	3.8	3.5
Frequency of unenthusiasm / disinterest in last 2 weeks	0.9	1.2	3.8	-0.4	-1.6	-1.8	0.7	-0.1	-0.8	-0.3	-0.2	-0.9	-1.4	0.9	-0.9	-1.1	-0.3	-1.9	-1.8	-0.8	-1.0
Hayfever, allergic rhinitis or eczema	0.9	2.0	4.7	-1.6	-1.7	-1.6	-0.3	0.3	-1.5	-2.2	-0.8	-1.5	-0.9	-2.1	-1.2	-1.4	-0.7	1.4	-1.2	-1.8	-1.8
Medication: Atenolol	0.9	1.1	4.8	0.4	0.4	0.5	-0.5	-1.6	-0.1	0.6	1.7	0.2	0.1	1.9	0.2	0.9	0.1	-2.2	0.4	1.6	1.4
Sitting height	0.9	6.5	15.7	2.6	2.6	2.6	2.8	0.1	3.0	4.0	1.1	3.0	2.8	1.5	2.9	2.1	-1.5	1.6	2.4	3.0	3.3
Leg predicted mass (left)	0.9	4.9	13.7	2.0	0.7	1.6	1.5	-1.5	1.9	3.3	-0.2	2.4	1.9	0.1	2.2	2.2	1.3	3.4	1.8	3.7	3.5
Trunk fat mass	0.9	3.8	9.6	1.8	1.2	1.4	2.3	-2.0	1.8	1.1	2.1	1.9	2.3	2.1	2.1	3.1	-0.8	-0.2	2.0	3.1	1.1
Medication: Simvastatin	0.9	1.4	3.9	-0.5	-1.5	-1.8	-0.6	-1.3	-1.2	-1.6	0.1	-0.9	-1.2	0.7	-1.1	0.5	0.1	-2.0	-1.4	-0.7	-1.3
Worrier / anxious feelings	0.9	1.7	2.8	1.1	1.7	0.9	1.3	-1.6	1.4	1.6	0.9	1.2	1.4	1.2	1.3	1.6	-0.6	-1.0	1.3	1.7	1.2
Pulse rate	0.9	1.6	3.3	-0.1	-1.3	-1.0	-0.4	1.4	-1.1	-1.8	-1.1	-0.4	-0.7	-1.8	-0.6	-1.6	-1.3	1.5	-1.8	-0.8	-1.8
Worry too long after embarrassment	0.9	1.5	3.1	1.5	1.8	1.3	1.4	-0.5	1.4	1.5	1.1	1.4	1.3	0.8	1.5	1.5	-1.2	-0.0	0.9	0.8	0.5
Emphysema/chronic bronchitis	0.9	1.0	3.5	-0.7	-0.4	-0.5	-1.2	-0.5	-1.7	-0.9	-1.5	-1.3	-1.2	-0.7	-1.4	-1.9	0.0	0.5	-0.5	-0.2	0.4
Heart disease (mother)	0.9	1.1	4.8	1.0	-0.6	0.3	1.0	-0.5	1.3	2.2	-0.0	1.5	0.7	1.3	1.2	0.5	0.5	0.5	-0.2	1.8	1.1
Knee pain experienced in last month	0.9	1.4	5.0	-0.7	-1.9	-1.9	0.4	-0.5	-0.8	-1.4	0.5	-0.8	-1.0	0.8	-0.6	-0.5	-0.5	-1.5	-1.8	-0.4	-2.2
Smoking status: Current	0.9	1.5	4.8	1.4	0.9	0.9	1.0	0.7	1.2	0.7	1.2	1.5	2.0	1.3	1.6	1.4	-0.7	0.1	0.7	2.2	-0.3
Risk taking	0.9	1.4	4.3	0.6	2.1	1.4	-0.1	-0.1	1.3	1.0	0.6	0.5	1.2	0.4	0.7	1.1	0.3	1.2	2.0	1.4	2.0
Unable to work because of sickness or disability	0.9	1.2	3.8	1.0	0.7	2.0	0.4	0.7	1.3	0.5	1.6	1.2	1.2	0.6	1.1	1.9	0.2	-0.3	1.4	0.5	0.3
Irritable Bowel Disease (IBD)	0.8	1.8	5.7	0.6	2.4	1.8	0.5	1.1	0.6	-0.9	2.1	0.4	1.6	0.6	0.8	2.0	-1.5	-1.1	2.1	0.7	0.4
Supplements: Zinc	0.8	0.9	3.1	1.5	0.5	1.2	0.3	0.8	0.8	0.7	-0.1	1.4	0.8	0.6	1.2	0.8	0.1	1.3	0.6	1.8	0.6
Supplements: Glucosamine	0.8	1.1	3.5	0.4	1.9	0.4	0.6	-1.1	0.0	-0.2	0.9	0.4	1.1	1.4	0.4	1.7	-0.7	-0.7	1.5	1.4	1.1
Had other major operations	0.8	0.9	3.5	0.3	1.9	0.9	0.4	0.5	0.9	-0.2	0.8	0.6	1.5	-0.3	0.9	1.2	-0.7	1.4	1.7	0.2	-0.3
Medication: Ramipril	0.8	1.1	4.2	-0.0	-1.3	-1.2	0.2	-0.4	-1.1	-1.2	1.2	-0.6	-0.7	0.9	-0.6	0.1	-1.2	-2.1	-1.1	-1.2	-1.2
Happiness	0.8	0.9	2.5	-0.7	-0.9	-1.6	-0.7	0.5	-0.5	-0.0	-1.2	-1.0	-1.3	-0.5	-0.9	-1.4	0.4	-0.8	-1.4	-1.2	-0.5
Loud music exposure frequency	0.8	0.8	5.2	0.6	-1.6	-0.7	-0.6	-1.7	0.1	-0.4	-0.3	0.4	-0.2	0.0	0.4	-0.3	-0.3	0.5	-1.5	0.0	-2.3
Health satisfaction	0.8	1.1	5.7	-0.1	0.3	-0.6	1.2	-2.4	0.6	0.4	1.2	0.2	0.9	0.9	0.7	1.6	-1.0	-1.4	0.4	1.5	0.1
Medication: Blood pressure	0.8	1.5	6.1	0.9	-0.6	0.1	1.3	-0.2	-0.2	-1.0	2.2	0.3	0.6	2.0	0.4	1.5	-1.9	-2.5	-0.1	0.4	-1.1
Medication: Omeprazole	0.8	0.9	3.7	-1.0	-0.4	-1.1	-0.0	1.2	-1.2	-1.9	-0.0	-1.2	-0.6	0.2	-0.9	-0.4	-0.2	-1.3	-0.8	-0.4	-1.5
Pulse rate, automated reading	0.8	2.6	6.9	-1.4	-2.1	-1.5	0.0	1.8	-2.1	-2.6	-0.7	-1.8	-1.6	-1.1	-1.8	-1.7	-0.7	-0.1	-1.9	-1.6	-1.9
Family relationship satisfaction	0.8	0.9	2.5	-1.0	-0.7	-1.6	0.2	-0.5	-1.1	-1.0	-0.9	-1.2	-1.3	-0.4	-1.1	-1.5	-0.1	-0.3	-1.1	-0.8	-1.1
Handedness (chirality/laterality): Left-handed	0.8	1.0	2.4	1.0	0.4	1.4	1.6	-1.2	0.6	1.0	0.7	0.9	1.1	1.3	1.1	0.7	-1.4	0.1	0.7	1.2	0.3
Ever had stillbirth, spontaneous miscarriage or termination	0.8	0.9	3.7	1.4	0.9	1.0	-0.9	-0.3	0.3	0.2	1.4	1.0	0.7	0.9	0.8	1.9	-0.1	-0.1	1.3	0.2	1.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.8	0.9	2.5	0.4	0.8	1.2	0.3	-1.5	0.3	0.3	0.7	0.1	0.1	1.6	0.1	1.2	-0.9	-1.6	1.2	0.8	1.5
Medication: Aspirin	0.8	1.0	3.8	-1.0	-1.8	-2.0	0.4	-1.0	-0.8	-0.1	-0.4	-0.7	-1.0	0.4	-0.6	-1.0	0.3	-0.8	-1.9	-0.4	-1.0
Illnesses of father: None of the above (group 1)	0.8	1.0	3.0	0.1	1.1	0.3	1.2	-0.3	1.3	1.7	-1.4	0.7	0.7	-0.7	0.8	-0.2	0.4	1.4	0.4	1.6	0.9
Illnesses of father: High blood pressure	0.8	1.0	5.6	-0.1	-0.4	-0.5	0.5	0.1	-0.7	-1.0	1.7	-0.5	0.1	1.4	-0.2	0.5	-2.4	-1.9	-0.7	-0.5	-1.0
Basal cell carcinoma (self-reported)	0.8	0.9	3.6	-1.8	-0.5	-0.9	-0.2	0.1	-1.1	-1.1	0.0	-1.4	-1.1	-0.6	-1.3	-0.5	0.6	-0.8	-0.4	-1.9	0.2
Pack years of smoking	0.8	1.1	4.1	0.5	0.8	1.9	0.9	-0.2	1.1	0.5	0.9	0.8	1.2	1.5	0.8	1.0	-0.0	-0.7	2.0	0.9	1.0
Reaction Time	0.7	1.3	4.1	-0.8	-2.0	-2.0	-0.5	-0.7	-0.9	-0.6	-0.5	-0.8	-1.3	0.0	-0.7	-0.7	-0.4	-1.9	-1.8	-0.9	-1.2
Blood Eosinophil Count	0.7	5.7	12.3	-1.5	-3.5	-2.1	-0.8	-0.3	-2.8	-2.7	-2.1	-2.3	-2.6	-3.1	-2.3	-3.1	2.1	2.2	-2.8	-2.2	-2.0
Allergy or Eczema	0.7	1.9	7.3	-0.9	-2.0	-1.2	0.9	0.6	-0.9	-2.0	-0.4	-0.8	-0.4	-1.7	-0.6	-1.5	-1.3	1.2	-1.4	-1.9	-2.7
Eye problems/disorders: Diabetes related eye disease	0.7	0.7	3.5	-0.7	-1.3	-1.1	-0.1	-1.1	-0.6	-0.3	-1.2	-0.6	-0.9	-0.7	-0.9	-0.8	1.9	0.1	-0.6	0.2	-0.1
Medication: Levothyroxine sodium	0.7	1.2	2.7	-0.7	-1.4	-1.6	1.6	0.4	-1.1	-1.0	-0.2	-0.8	-0.5	-0.9	-0.5	-0.0	-1.5	1.1	-1.5	-1.0	-1.5
Waist circumference	0.7	2.4	8.3	1.5	0.6	1.4	1.2	-1.4	1.1	0.3	2.4	1.5	2.0	1.5	1.7	2.9	-0.7	-0.3	1.8	2.2	0.7
Time employed in main current job	0.7	0.8	4.2	0.9	0.6	0.8	-0.2	2.0	1.0	1.1	0.8	1.0	1.0	0.4	1.1	0.7	0.1	0.2	0.7	-0.7	-0.0
Hair/balding pattern: Pattern 3	0.7	1.0	3.5	0.8	1.4	1.2	1.4	1.9	1.3	0.4	0.1	1.1	1.1	0.3	0.8	0.7	-0.7	0.4	1.6	0.5	0.0
Mouth/teeth dental problems: Dentures	0.7	1.2	5.9	-0.2	0.4	0.3	0.0	-1.1	0.2	0.2	1.6	-0.2	0.4	1.4	-0.0	2.4	1.3	-2.3	1.2	0.3	0.9
Medication: Cholesterol lowering	0.7	1.1	3.3	1.2	-0.1	0.4	1.2	-0.5	-0.4	-1.0	1.8	0.5	0.4	1.6	0.2	1.6	-1.7	-1.4	0.4	1.4	0.2
Illnesses of mother	0.7	0.9	2.7	-0.1	0.1	-0.2	-1.2	0.9	-0.9	-0.8	-1.4	-0.7	-1.2	-1.7	-0.9	-1.4	0.9	1.1	-0.5	-0.7	-0.3
Mouth/teeth dental problems: Bleeding gums	0.7	0.9	3.5	-1.1	-0.6	-1.2	-0.5	0.5	-1.2	-1.2	0.1	-1.5	-1.1	1.0	-1.3	0.0	0.4	-1.9	-0.7	-0.1	-0.2
Chronic bronchitis/emphysema (mother)	0.7	0.9	3.1	-1.3	0.2	-0.9	-0.8	-1.3	-1.0	-1.8	0.3	-1.5	-0.3	0.0	-1.1	0.1	-0.4	-1.3	-0.1	-0.6	-0.9
Whole body fat mass	0.7	3.1	8.8	1.9	0.8	1.2	1.7	-2.1	1.5	0.8	2.0	1.8	2.1	2.0	2.0	3.0	-0.6	-0.1	1.6	2.9	0.7
Leg fat mass (right)	0.7	2.5	7.0	2.0	0.5	1.0	1.3	-1.9	1.2	0.6	2.0	1.8	1.9	1.7	1.9	2.6	-0.8	0.3	1.1	2.6	0.4
Qualifications: NVQ or HND or HNC or equivalent	0.7	0.9	5.8	0.6	0.3	0.9	-0.8	-0.6	-0.1	0.6	-1.0	0.4	0.3	-0.1	0.1	0.3	2.4	1.1	1.0	0.8	1.6
Smoking status: Previous	0.7	1.0	2.8	-1.1	-0.5	-0.5	-1.1	-0.1	-1.7	-1.5	0.4	-1.6	-1.4	-0.0	-1.5	0.5	1.0	-1.3	0.1	-0.5	0.7
Medication for cholesterol	0.7	1.0	2.1	1.0	1.4	1.5	0.9	-0.3	0.8	0.5	1.1	1.0	1.1	0.5	0.9	1.2	-1.3	0.3	1.2	1.0	1.0
Mineral and other dietary supplements	0.7	0.9	4.1	-0.5	-1.5	-0.8	0.1	0.4	-0.3	0.1	-1.4	-0.8	-0.9	-1.3	-0.8	-1.2	2.0	1.0	-0.9	-0.5	-0.1
Mother’s age at death	0.7	0.9	4.8	0.1	2.1	1.2	-0.5	0.3	-0.3	0.1	0.1	-0.2	0.2	0.3	-0.4	0.7	0.4	-0.2	1.8	-0.1	2.2
Myopia	0.7	1.0	2.6	-0.8	-0.7	-0.7	-0.9	0.3	-0.7	-1.4	-1.1	-0.8	-0.6	-1.6	-0.6	-1.3	0.3	1.3	-0.6	-1.5	-1.2
Medication: Omeprazole (e.g. Zanprol)	0.7	0.9	4.0	-0.6	0.2	-0.8	0.2	1.1	-1.1	-2.0	0.6	-1.0	-0.3	0.8	-0.7	0.9	-0.4	-1.6	-0.3	-0.6	-1.2
Leg fat mass (left)	0.7	2.6	7.2	2.0	0.4	1.1	1.3	-2.0	1.3	0.8	1.9	1.8	1.9	1.6	1.9	2.6	-0.6	0.4	1.1	2.7	0.5
Depressed Affect (Nagel 2018)	0.6	1.2	3.5	1.4	1.2	-0.2	1.9	0.7	1.0	1.2	0.7	1.3	1.2	0.4	1.3	1.6	-0.5	0.4	0.5	1.4	0.3
Prostate Cancer	0.6	0.9	5.1	1.2	-0.3	0.1	-0.7	-2.0	-0.0	-0.7	-0.0	0.7	-0.3	0.0	0.3	-0.4	-0.5	0.8	-0.9	-1.1	-2.3
Cardiovascular Disease	0.6	2.0	4.8	-0.9	-2.1	-2.2	0.1	-0.3	-2.1	-1.9	-1.3	-1.5	-1.4	-1.5	-1.5	-0.0	1.2	1.0	-1.8	0.1	-0.8
Hand grip strength (left)	0.6	1.5	7.4	0.7	1.0	0.5	0.4	0.0	0.4	2.4	-1.2	0.5	-0.4	-0.7	-0.1	-1.0	1.5	2.3	0.2	1.1	2.7
Frequency of depressed mood in last 2 weeks	0.6	0.8	2.3	1.3	-0.1	0.3	0.9	0.8	1.2	1.5	0.4	1.1	0.6	1.5	0.9	1.0	-1.0	-0.6	-0.2	0.2	0.1
Hearing difficulty/problems: Yes	0.6	1.0	2.7	1.3	0.8	0.5	1.6	0.4	0.8	1.2	0.1	1.1	0.6	1.1	0.9	1.3	0.6	-0.3	1.0	1.5	1.2
Angina	0.6	0.8	4.3	0.5	0.5	1.0	0.3	0.1	0.0	0.1	1.2	0.4	0.4	2.1	0.3	0.9	0.1	-1.0	1.2	1.7	1.0
Taking other prescription medications	0.6	1.0	3.8	-0.3	-0.5	-0.7	2.0	-1.6	-0.1	-0.8	1.4	-0.2	0.5	0.6	0.3	1.1	-1.3	-0.9	-0.5	-0.2	-1.8
Bilateral oophorectomy (both ovaries removed)	0.6	0.7	4.3	-0.2	0.4	0.3	1.0	0.3	-0.6	-0.3	-0.5	-0.5	0.2	-0.9	-0.3	0.1	0.1	1.8	0.2	2.1	1.1
Heel bone mineral density (BMD) T-score, automated (left)	0.6	1.4	5.1	-0.1	-1.8	-0.7	-1.8	0.2	-0.3	-0.6	-0.7	-0.3	-0.7	-0.5	-0.3	-1.1	1.6	0.1	-1.6	-2.3	-2.2
Alcohol usually taken with meals	0.6	0.9	3.6	-1.6	0.5	-0.5	1.3	1.9	-0.8	-1.1	-1.2	-1.2	-0.5	-0.6	-1.2	-0.9	-0.2	-0.0	0.6	-0.2	-0.1
Hip circumference	0.6	2.7	11.8	2.1	1.0	1.3	1.1	-1.4	1.1	1.0	1.4	1.7	1.8	1.3	1.8	2.5	-0.7	1.2	1.4	3.4	1.2
Alcohol intake versus 10 years previously	0.6	0.8	9.4	-0.1	-0.8	-0.7	-0.7	-3.1	-0.1	0.1	-0.8	0.0	0.1	-0.5	0.3	0.5	1.3	0.1	-0.7	0.2	-0.7
Medication: Lansoprazole	0.6	0.6	4.9	-0.4	-0.2	-1.3	-0.2	-2.2	-0.8	-0.8	-0.5	-0.5	-0.7	-0.2	-0.6	0.2	0.9	0.1	-0.4	1.0	-0.2
Prospective memory result	0.6	0.8	2.8	0.1	-1.1	-0.7	-0.4	-0.9	-1.3	-1.3	0.0	-0.6	-1.0	0.4	-0.6	-0.9	-1.7	-1.0	-1.0	-0.0	-0.9
Hair/balding pattern: Pattern 4	0.6	1.3	5.4	0.3	0.3	0.2	0.2	-1.6	0.3	1.2	1.4	0.2	0.7	2.3	0.5	1.7	-0.9	-1.7	0.5	1.4	1.7
Birth weight of first child	0.6	1.1	4.2	0.1	-0.8	0.4	-0.7	0.0	-1.5	-0.9	-1.7	-0.6	-1.0	-1.7	-1.0	-1.1	0.6	2.1	-0.1	-0.2	0.8
Medication: Amlodipine	0.6	0.8	2.1	1.3	-0.1	0.8	0.5	-0.0	1.0	0.8	1.3	1.1	1.1	1.5	1.1	1.1	-0.7	-0.5	-0.1	0.7	-0.6
Birth weight	0.6	1.3	4.4	1.3	0.5	0.8	-0.6	-1.7	0.6	1.5	-0.4	0.9	0.3	-0.5	0.8	0.6	2.0	1.5	0.3	2.1	1.5
Age at first live birth	0.6	1.0	2.3	1.0	1.3	1.3	-0.5	-0.6	1.1	1.4	0.4	1.5	1.1	1.1	1.2	0.3	0.1	-0.4	1.1	1.2	0.6
Mean time to correctly identify matches	0.6	1.2	5.9	-0.6	-1.9	-1.9	-0.2	-0.4	-0.7	-0.3	-0.5	-0.8	-1.3	0.5	-0.8	-0.1	0.1	-2.4	-1.6	-0.6	-0.9
Medication: Aspirin	0.6	0.8	2.6	-0.9	-1.5	-1.6	0.7	-0.7	-0.7	0.0	-0.3	-0.5	-1.0	0.7	-0.6	-0.9	0.1	-0.8	-1.5	-0.5	-0.7
Average weekly red wine intake	0.6	0.9	4.3	-1.9	0.6	-0.7	0.8	2.1	-1.1	-0.8	-0.2	-1.5	-0.2	-0.1	-1.1	-0.2	-0.3	-0.4	0.8	-0.4	0.6
Ever had bowel cancer screening	0.6	0.7	5.4	-0.1	-1.3	-0.7	-0.2	0.5	-0.2	-1.0	0.0	-0.4	-0.2	-1.1	0.1	0.6	0.1	0.7	-0.9	-0.7	-2.3
Mouth/teeth dental problems: Mouth ulcers	0.6	1.0	2.6	-1.3	-0.0	-1.4	1.2	-0.1	-1.1	-0.5	-0.4	-1.4	-0.9	0.3	-1.4	0.0	-0.6	-1.5	0.2	0.9	1.6
Miserableness	0.6	1.1	2.2	1.3	1.0	0.3	1.3	0.8	1.0	1.4	0.9	1.3	0.9	1.4	1.2	1.1	-1.5	-0.8	0.2	0.6	0.1
Guilty feelings	0.6	0.9	1.8	0.9	1.3	0.8	0.7	0.1	1.1	1.3	0.4	0.9	1.1	0.3	1.0	0.8	-0.0	1.1	1.3	1.2	1.0
Hearing aid user	0.6	0.7	4.8	0.8	-0.0	0.0	-1.3	-2.2	0.2	0.7	0.3	0.1	-0.0	0.9	0.0	0.5	0.8	-1.1	-0.1	1.1	0.9
Supplements: Fish oil (including cod liver oil)	0.6	0.8	7.0	-0.1	0.6	0.2	0.4	1.3	-0.1	-0.6	1.5	0.3	0.5	0.7	0.4	0.5	-2.6	-1.0	-0.1	-0.3	-1.1
Alcohol drinker status: Never	0.6	0.7	2.9	-0.2	0.1	-0.2	-1.6	-0.4	-0.1	-0.1	-1.1	0.1	-0.5	-0.9	-0.2	-1.5	0.9	1.7	-0.8	-0.4	-0.5
Age started oral contraceptive pill	0.6	0.7	2.1	-0.2	-1.3	-0.9	0.3	-0.4	-0.4	-0.4	-0.9	-0.5	-0.9	-1.1	-0.5	-1.0	-0.2	0.7	-1.4	-1.1	-1.5
Impedance of whole body	0.6	3.0	11.9	0.2	2.7	0.6	2.2	-0.5	1.8	1.0	2.2	0.6	1.7	2.7	1.2	1.4	-2.4	-3.5	1.2	0.6	0.0
Depression (Nagel 2018)	0.5	0.7	2.5	0.0	-1.6	-1.3	1.1	0.1	-0.1	0.4	-0.1	-0.1	-0.7	0.7	-0.2	-0.6	-0.7	-1.1	-1.6	-0.9	-0.9
Schizophrenia vs Biploar Disorder	0.5	0.6	2.7	0.3	-0.6	0.1	0.1	1.6	-0.0	0.1	-1.1	0.3	-0.4	0.1	-0.2	-1.6	1.4	1.1	-0.5	-0.4	-0.0
Alzheimer’s Disease (in mother)	0.5	0.5	2.0	-1.2	0.6	-0.2	1.4	-0.8	0.0	-0.2	-0.2	-0.7	0.3	-0.6	-0.4	0.1	0.6	-0.3	1.4	-0.1	1.3
HbA1C	0.5	0.5	1.4	0.2	0.5	1.2	1.1	-0.6	0.9	0.4	0.6	0.5	0.9	1.0	0.6	0.7	-0.6	-0.9	0.8	0.7	0.2
Lupus	0.5	0.8	2.6	-1.0	1.0	0.2	-0.2	1.2	-0.3	-0.3	-1.4	-0.9	0.1	-1.6	-0.7	-0.3	0.6	0.8	1.2	0.2	1.3
Lung FEV1/FVC ratio	0.5	2.7	13.2	-1.4	-0.6	-0.7	-1.2	-0.5	-0.5	0.1	-1.7	-1.0	-0.7	-3.6	-0.8	-1.4	3.4	3.1	-0.2	0.6	1.1
Average weekly spirits intake	0.5	0.6	2.9	-0.5	1.3	0.1	0.0	-0.2	-0.4	-0.0	-0.9	-0.6	-0.7	0.9	-0.8	-0.7	0.7	-0.9	0.5	1.0	1.7
Trunk fat percentage	0.5	2.1	6.4	0.8	0.5	0.4	1.8	-2.0	0.7	-0.6	2.2	0.7	1.4	2.1	1.1	2.5	-1.4	-1.8	1.1	1.4	-0.6
Townsend deprivation index at recruitment	0.5	0.7	3.3	1.0	-0.3	0.4	0.4	0.2	0.0	-0.0	1.4	0.4	0.5	1.4	0.5	1.8	-0.3	-0.5	0.4	1.4	0.2
Maternal smoking around birth	0.5	0.7	3.8	-1.0	-1.0	-1.0	-0.3	-0.4	-0.5	-1.0	-0.2	-0.8	-0.6	0.9	-0.4	0.3	0.1	-2.0	-0.8	0.2	-1.4
Tinnitus: Yes, but not now, but have in the past	0.5	0.6	1.4	-0.5	-1.0	-0.7	-1.2	-1.1	-0.6	-0.6	-0.8	-0.6	-0.9	-0.3	-0.5	-0.7	1.1	-0.2	-0.9	-0.2	-0.8
Hair/balding pattern: Pattern 2	0.5	0.6	1.8	-0.2	-0.1	0.3	-0.6	-1.2	0.1	0.8	-1.3	0.3	-0.1	-0.3	0.3	-1.1	1.3	1.3	-0.3	1.2	0.3
Qualifications: None of the above	0.5	1.0	4.6	-0.2	-0.2	0.3	0.7	-0.6	0.3	-0.7	2.2	0.1	0.3	1.5	0.6	1.1	-1.1	-2.0	0.2	-0.2	-1.4
Pain all over the body in last month	0.5	0.5	2.7	0.2	0.9	0.8	0.2	1.6	0.4	0.6	0.0	0.6	0.5	0.2	0.4	0.3	-0.9	0.4	1.1	-0.3	1.1
Fluid intelligence score	0.5	1.0	4.2	0.5	0.7	0.6	2.1	0.2	0.8	1.2	-0.5	0.5	0.9	-0.4	0.3	0.2	0.9	1.6	1.1	0.9	1.6
Qualifications: A levels/AS levels or equivalent	0.5	1.2	5.1	-1.2	-0.1	-0.9	-0.4	0.2	-0.6	-0.2	-2.3	-1.1	-0.7	-2.0	-1.2	-1.8	0.6	1.6	0.0	-0.7	0.5
Pulse wave Arterial Stiffness index	0.5	0.6	2.9	0.3	0.2	-0.1	-0.2	-1.7	0.4	0.6	-1.1	0.0	-0.1	-0.5	0.0	-0.4	0.4	1.3	-0.2	1.6	1.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.7	3.8	-0.3	-1.0	-0.5	0.4	1.0	-0.6	-0.3	0.6	-0.5	-0.6	1.0	-0.4	-0.4	-1.9	-0.9	-1.2	-0.2	-0.9
Qualifications: College or University degree	0.5	1.5	3.6	-1.5	-1.2	-1.7	1.1	0.7	-1.0	-0.3	-1.2	-1.4	-1.3	-1.8	-1.5	-1.9	-0.2	0.5	-1.2	-1.6	-0.0
Medication: Seretide 50 evohaler	0.5	0.6	1.9	-0.4	-1.3	-0.5	0.6	0.0	-0.6	-0.9	0.3	-0.7	-0.8	-1.0	-0.6	-0.4	0.8	0.2	-0.7	-1.4	-1.1
Had major operations	0.5	0.6	2.5	-0.7	-0.1	-0.9	-0.3	-0.5	-0.4	0.4	-1.6	-0.6	-0.5	-0.9	-0.7	-0.4	1.2	1.3	-0.2	0.5	1.0
Illness, injury, bereavement, stress in last 2 years	0.5	0.6	5.4	-0.5	0.3	-0.4	-0.2	0.3	-0.5	-0.4	-0.4	-0.7	-0.9	-0.8	-0.7	-0.3	2.3	0.9	0.2	-0.7	0.5
Long-standing illness, disability or infirmity	0.5	0.8	4.9	0.9	-0.0	-0.1	0.8	-0.7	0.4	-0.3	1.4	0.4	1.0	0.7	0.8	2.2	-0.7	-0.4	-0.0	1.1	-0.7
Friendships satisfaction	0.5	0.6	2.2	-0.6	-0.1	-1.3	1.3	-1.5	0.2	0.4	0.9	-0.4	-0.4	0.2	-0.1	0.4	-0.3	-0.9	-0.7	-0.5	-1.1
Qualifications: nursing, teaching	0.5	0.8	2.7	-0.7	0.2	-0.4	0.3	-1.1	0.8	1.6	-0.9	0.0	0.6	-1.0	0.3	-0.4	0.9	1.5	0.3	1.2	1.3
Commuting to job workplace: Walk	0.5	0.6	1.5	-0.6	-0.6	-0.8	-1.2	-0.8	-1.0	-0.7	0.7	-1.2	-0.7	-0.3	-0.8	-0.2	-1.1	-0.4	-0.8	-0.3	0.1
Osteoporosis (self-reported)	0.5	0.7	2.8	-1.0	-0.9	-1.1	0.3	-0.3	-0.6	-1.3	-0.4	-0.9	-0.5	-0.5	-0.7	-1.0	0.3	0.2	-0.3	-1.7	-1.0
Average weekly champagne plus white wine intake	0.5	0.7	3.5	0.5	-1.0	-0.8	0.4	1.9	-0.8	-1.4	0.0	-0.4	-0.7	-0.2	-0.5	0.8	0.2	-0.1	-0.9	-1.0	-1.4
Financial situation satisfaction	0.5	0.6	1.8	0.6	-1.1	-1.1	-0.4	-0.8	0.4	0.3	-0.4	0.5	0.3	-0.7	0.7	0.1	0.4	1.3	-1.3	0.5	-1.3
Supplements: Calcium	0.5	0.6	2.4	0.6	0.9	0.3	0.3	1.6	0.2	-0.7	0.4	0.4	0.8	0.2	0.5	1.2	-1.3	0.4	1.0	0.3	-0.6
Bipolar Disorder (2018)	0.4	0.7	4.2	-0.8	-0.0	-0.2	0.9	-1.0	-0.4	-0.5	1.1	-0.8	0.1	0.7	-0.3	0.3	-2.0	-1.5	-0.1	0.3	-0.3
Alzheimer’s Disease (including proxy)	0.4	0.6	2.4	-1.0	0.1	-0.5	-0.1	0.2	-0.7	-0.8	-1.0	-0.9	-0.2	-1.5	-0.8	-0.5	1.4	0.9	0.5	-0.0	0.6
Crohns Disease (2017)	0.4	0.8	2.5	0.6	1.6	1.5	0.0	1.4	0.7	-0.0	1.1	0.3	1.1	-0.2	0.6	1.4	0.0	0.4	1.3	0.5	0.8
Major Depression (MDD)	0.4	0.5	2.2	-0.0	-0.4	0.0	-0.8	-0.8	-0.4	-1.1	-0.4	-0.3	-0.4	-0.4	-0.4	-0.7	-1.5	-0.4	-0.5	-1.0	-1.3
Verbal and Numeric Reasoning (VNR)	0.4	0.9	2.6	0.6	0.5	0.2	1.1	-0.9	1.1	1.6	-0.3	0.8	0.9	-0.4	0.7	0.8	1.3	1.5	0.7	0.8	1.1
Breast Cancer	0.4	0.9	2.4	-0.8	-1.0	-1.0	-1.5	-0.5	-1.4	-1.4	-0.3	-0.9	-0.9	-0.8	-1.0	-1.2	-0.4	0.6	-1.4	0.2	-0.9
Crohns Disease (2012)	0.4	0.7	3.7	-0.2	0.9	0.3	-0.8	1.2	-0.3	-0.3	-0.4	-0.4	0.1	-0.9	-0.5	0.6	1.9	1.0	1.1	0.7	1.2
Primary Biliary Cirrhosis	0.4	0.5	2.5	0.3	0.8	0.8	-0.3	1.5	-0.0	0.1	-0.2	0.1	-0.0	-0.7	-0.0	0.7	1.6	0.6	0.8	0.9	1.0
Rheumatoid Arthritis	0.4	0.6	3.0	-0.8	0.4	-0.0	-1.1	0.8	-0.3	-0.3	-1.7	-0.6	-0.7	-0.5	-1.0	-1.2	1.0	0.2	0.1	-0.2	0.4
Hypothyroidism (self reported)	0.4	0.9	2.7	-0.6	-1.0	-1.6	0.8	-0.9	-1.4	-0.9	-0.5	-0.8	-0.8	0.2	-0.7	-0.9	-1.0	0.2	-1.5	-0.2	-1.4
Type 2 Diabetes (T2D) (2018)	0.4	0.7	2.9	0.4	0.6	-0.4	0.3	-1.5	0.5	0.2	-0.1	0.4	0.7	-0.9	0.6	0.9	1.5	1.7	0.2	1.1	-0.1
Relative age of first facial hair	0.4	0.9	2.3	-1.2	-0.4	-0.8	-1.2	1.0	-0.8	-0.3	-1.1	-1.1	-1.3	-0.1	-1.3	-1.5	1.2	-0.3	-0.2	-0.5	0.9
Other serious medical condition/disability diagnosed by doctor	0.4	0.5	2.8	-0.4	0.3	-0.2	1.7	-0.8	0.0	0.5	0.2	-0.4	0.5	0.6	0.0	0.5	-0.2	-0.9	0.6	1.0	1.2
Ever used hormone-replacement therapy (HRT)	0.4	0.5	2.1	0.0	-1.5	-0.9	-0.5	-0.6	-0.7	-0.7	0.0	-0.2	-0.6	-0.3	-0.2	0.2	-0.3	0.2	-1.4	-0.3	-1.2
Medication for hormone replacement therapy	0.4	0.5	2.2	0.4	0.3	0.7	1.1	1.5	0.3	-0.2	1.4	0.2	0.4	0.5	0.4	0.7	-1.0	-0.4	0.3	0.2	-0.3
High blood pressure	0.4	1.2	4.2	-0.2	-1.6	-1.9	1.1	-0.1	-1.1	-1.5	0.3	-0.9	-0.7	-0.5	-0.6	0.2	-0.8	-0.4	-1.7	-0.3	-2.1
Stomach or abdominal pain in last month	0.4	0.5	3.6	0.6	0.0	-0.2	0.1	0.1	0.7	0.5	0.8	0.9	0.8	1.1	1.0	0.6	-1.9	-0.0	0.2	0.1	-0.4
Past tobacco smoking	0.4	0.7	2.2	0.9	0.8	0.3	0.9	-0.4	1.5	1.4	-0.6	1.3	0.9	-0.3	1.2	-0.4	-0.5	1.3	0.1	-0.1	-0.2
Financial difficulties in last 2 years	0.4	0.6	1.6	1.3	-0.6	0.8	-0.6	0.1	0.6	0.6	0.4	1.1	0.8	0.5	0.9	-0.1	-1.2	0.1	-0.5	1.2	-0.2
Diabetes (self-reported)	0.4	0.6	3.3	0.8	0.4	-0.4	0.3	-1.8	0.5	0.1	0.6	0.8	0.8	0.4	0.8	1.0	1.0	0.6	0.1	1.0	-0.5
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.5	1.4	-0.5	-1.2	-0.7	-0.9	0.7	-0.8	-0.4	-0.3	-0.5	-0.8	-0.7	-0.6	-0.8	-0.1	0.1	-1.1	-0.9	-0.7
Hypothyroidism/myxoedema (self-reported)	0.4	0.8	2.6	-0.5	-1.1	-1.6	1.1	-0.5	-1.2	-0.5	-0.5	-0.6	-0.8	-0.4	-0.7	-0.7	-0.4	0.8	-1.5	-0.6	-1.0
Medication: Ventolin 100micrograms inhaler	0.4	0.5	2.2	-1.0	-0.2	0.1	-0.0	-0.6	-0.7	-0.6	0.3	-0.8	-0.2	0.7	-0.8	-0.7	-0.7	-1.5	0.4	-0.8	0.5
Body fat percentage	0.4	1.7	5.6	1.0	0.2	0.3	1.2	-1.9	0.5	-0.9	2.3	0.8	1.3	1.8	1.1	2.4	-1.2	-1.4	0.8	1.2	-1.0
Leg fat percentage (right)	0.4	1.5	5.5	1.3	-0.0	0.1	0.8	-1.6	0.2	-1.0	2.4	0.9	1.1	1.7	1.0	1.9	-1.3	-1.0	0.2	1.2	-1.4
Exposure to tobacco smoke outside home	0.4	0.5	1.9	1.2	0.9	0.4	0.1	0.1	0.3	0.7	0.5	0.7	1.1	0.4	0.9	0.9	0.1	1.0	0.3	1.4	0.4
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.5	2.7	0.3	1.1	0.0	-0.2	1.6	0.2	-0.5	0.3	-0.1	0.5	0.4	0.2	1.5	-0.9	0.1	0.5	0.1	-0.2
Pulse wave peak to peak time	0.4	0.5	2.6	0.1	0.2	0.5	0.5	1.6	0.0	0.1	1.2	0.4	0.5	0.9	0.4	0.9	-0.4	-1.2	0.6	-0.7	-0.5
Angina (self-reported)	0.4	0.5	2.9	0.2	0.2	0.7	-0.2	-0.3	-0.3	-0.1	0.7	0.1	-0.0	1.7	0.0	0.4	0.4	-0.9	0.7	1.5	0.9
Medication: Allopurinol	0.4	0.6	1.6	-0.8	-0.7	-0.7	0.1	0.5	-0.9	-1.1	0.4	-0.9	-0.5	-0.1	-0.8	-0.3	-0.9	-1.2	-0.7	-1.3	-0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.4	2.7	0.0	0.5	-0.2	-0.2	1.2	0.2	-0.0	0.4	0.2	0.3	1.3	0.4	-0.2	-0.5	-0.6	0.0	1.6	-0.2
Arm fat mass (left)	0.4	1.6	6.8	1.6	0.2	1.0	0.7	-1.3	0.9	0.1	1.5	1.5	1.4	1.1	1.5	2.6	-0.3	0.4	1.1	1.8	0.0
Commuting to job workplace: Public transport	0.4	0.4	2.3	-0.5	-1.0	-0.9	0.0	0.3	-0.5	-0.9	0.2	-0.3	-0.4	-0.7	-0.3	-0.3	-0.5	-0.2	-0.8	-0.4	-1.5
Leg fat percentage (left)	0.4	1.4	4.5	1.4	-0.1	0.2	0.6	-1.8	0.4	-0.8	2.1	0.9	1.1	1.5	1.1	1.9	-1.0	-0.8	0.3	1.3	-1.1
Average weekly beer plus cider intake	0.4	0.6	4.4	0.9	0.3	0.9	-2.1	-0.5	0.2	0.1	1.1	0.7	0.1	1.2	0.5	0.6	-0.1	-0.4	0.2	-0.1	0.1
Vascular/heart problems diagnosed by doctor	0.4	1.2	4.3	0.0	1.9	1.9	-0.3	0.0	1.1	1.5	0.1	0.8	0.7	0.6	0.7	-0.1	0.2	-0.1	2.0	0.2	2.1
Mean Putamen Volume	0.3	0.3	1.6	-0.0	1.3	0.5	0.2	0.6	0.6	0.4	-0.3	0.2	0.6	0.8	0.2	-0.2	-0.1	-0.7	0.9	0.4	0.7
Blood White Count	0.3	2.2	15.4	1.0	-3.4	-0.1	-0.5	-0.3	0.1	-1.2	1.3	0.5	-0.0	0.1	0.9	0.7	-0.7	-0.5	-2.1	-1.1	-3.9
BMI	0.3	1.8	7.7	-0.7	-2.5	-1.2	-1.2	-0.6	-1.7	-2.8	-0.2	-0.9	-1.1	-1.5	-0.9	0.1	0.5	0.4	-1.1	-1.0	-2.1
Smoking Status	0.3	0.6	2.6	-0.3	0.5	0.0	-0.5	0.8	-0.8	-1.2	1.1	-0.4	0.3	0.6	-0.4	1.6	0.6	-0.9	0.8	1.1	0.3
Medication: Metformin	0.3	0.5	2.9	0.3	0.1	0.0	-0.7	-0.9	0.2	0.3	-0.2	0.2	0.2	0.3	0.2	0.9	1.7	0.2	0.1	1.5	0.7
Diabetes (mother)	0.3	0.4	1.1	0.2	-0.9	0.0	0.3	0.9	0.8	1.0	-0.5	0.9	0.3	-0.1	0.8	-0.2	1.0	0.8	-0.3	-0.5	-0.5
Relative age voice broke	0.3	0.5	1.7	-0.7	1.0	-0.2	-0.2	0.2	0.6	0.9	-1.1	-0.1	-0.0	0.7	-0.1	-1.2	-0.1	-0.4	0.5	0.6	1.3
Chronic bronchitis/emphysema (father)	0.3	0.3	1.1	0.6	0.4	0.8	0.5	-0.1	0.7	0.1	1.1	0.4	0.8	0.4	0.5	0.9	-0.0	-0.3	0.7	0.6	0.0
High blood pressure (mother)	0.3	0.4	2.0	0.8	0.2	0.1	0.2	-0.8	0.2	0.4	0.4	0.7	0.9	0.3	0.7	0.8	-0.7	1.0	0.1	1.4	-0.1
Impedance of arm (right)	0.3	1.4	9.9	-0.8	1.6	-0.2	1.8	-0.5	0.4	-0.5	1.0	-0.6	0.6	1.3	-0.0	0.7	-1.7	-3.1	0.7	-0.4	-0.8
Arm fat percentage (right)	0.3	1.1	5.4	0.3	-0.6	-0.3	0.0	-1.5	-0.6	-2.3	1.6	-0.1	0.3	0.5	0.1	1.8	-0.8	-1.0	0.2	-0.1	-1.9
Number of live births	0.3	0.5	2.3	-0.2	0.3	-0.4	0.8	-1.4	0.2	-0.1	-0.8	0.0	-0.1	-1.0	0.0	-0.3	1.1	1.5	-0.1	-0.1	-0.1
Asthma	0.3	0.6	1.8	-0.6	-1.3	-0.6	-0.7	-0.2	-0.8	-0.1	-1.1	-0.8	-0.8	0.1	-0.9	-1.3	0.4	-0.5	-0.7	-0.5	0.4
Impedance of arm (left)	0.3	1.4	5.8	-0.4	2.2	0.3	1.9	-0.8	1.2	0.3	1.0	0.0	1.1	1.3	0.5	0.8	-1.7	-2.4	1.1	-0.1	-0.4
Arm fat mass (right)	0.3	1.3	6.0	1.3	0.2	0.8	0.7	-1.5	0.6	-0.0	1.3	1.1	1.2	0.9	1.2	2.4	-0.2	0.4	1.1	1.8	0.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.5	2.2	-1.4	0.5	-1.4	-0.4	-1.5	-0.4	0.5	-0.3	-0.8	-0.1	0.3	-0.6	-0.3	-0.2	0.1	0.1	1.0	0.8
Qualifications: O levels/GCSEs or equivalent	0.3	0.4	3.2	0.4	0.5	0.2	0.5	0.1	0.2	0.3	-0.8	0.3	0.7	-1.1	0.4	-0.0	-0.0	1.8	0.7	0.6	0.5
Gout (self-reported)	0.3	0.5	2.3	0.9	0.0	0.6	0.3	1.2	0.6	0.3	0.7	0.8	0.6	0.5	0.7	0.4	-1.5	-0.1	-0.1	-0.4	-0.2
Number of full brothers	0.3	0.3	1.4	0.8	0.3	0.1	-0.0	-1.0	0.4	0.5	1.2	0.6	0.3	0.2	0.8	0.9	-0.2	-0.0	-0.4	-0.2	-0.7
Eye problems/disorders: None of the above	0.3	0.4	1.3	0.5	0.3	1.1	-0.6	0.3	0.8	0.4	0.8	0.7	0.7	0.5	0.7	0.3	-0.3	0.4	0.8	-0.4	-0.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.4	3.0	0.1	0.1	0.5	-0.6	-0.6	-0.2	0.4	0.6	0.3	0.2	0.9	0.3	-0.0	-1.1	-0.5	0.0	1.7	0.3
Alcohol intake frequency.	0.3	0.7	3.4	0.2	-0.3	0.1	-0.0	-1.9	0.6	0.8	-1.1	0.6	0.1	-0.4	0.6	0.1	1.7	1.3	-0.4	0.7	-0.2
Overall health rating	0.3	0.6	1.9	0.5	-0.1	-0.6	0.7	-0.4	0.0	0.4	0.8	0.3	0.8	1.4	0.6	1.4	-1.1	-1.3	-0.1	1.1	0.1
Commuting to job workplace: Car/motor vehicle	0.3	0.4	1.2	0.3	0.3	0.4	0.7	0.0	0.8	0.7	0.6	0.6	0.8	0.7	0.6	1.0	1.1	-0.3	0.4	0.5	0.2
Hypertension (Self-reported)	0.3	0.8	2.3	-0.3	-1.4	-1.5	0.9	-0.4	-1.1	-1.3	0.4	-0.8	-0.5	-0.1	-0.6	0.2	-0.5	-0.7	-1.4	-0.1	-1.4
Diabetes diagnosed by doctor	0.3	0.5	4.1	0.4	0.3	-0.6	-0.0	-2.0	0.3	0.1	-0.1	0.3	0.5	-0.2	0.4	0.8	1.2	0.7	0.0	1.2	-0.0
Asthma (self-reported)	0.3	0.6	2.1	-0.6	-1.4	-0.5	-0.7	-0.1	-0.6	0.0	-1.3	-0.8	-0.9	-0.2	-0.9	-1.3	0.8	-0.2	-0.7	-0.6	0.4
Ever taken oral contraceptive pill	0.3	0.3	1.2	0.2	-0.6	0.1	1.1	0.4	-0.5	-0.0	-0.2	0.2	0.1	-0.6	0.3	-0.4	-1.1	0.9	-0.2	1.0	0.2
Medication: Atorvastatin	0.3	0.4	2.7	0.5	0.3	0.5	0.7	-0.0	0.1	-0.0	-0.4	0.0	0.4	-0.8	0.1	0.2	0.7	1.6	0.7	1.1	0.8
Fractured/broken bones in last 5 years	0.3	0.4	2.0	0.6	-1.4	-0.4	-0.2	-0.7	-0.7	-0.2	-0.0	0.3	-0.5	0.2	0.1	-0.3	-0.7	-0.1	-1.3	0.7	-1.1
Bipolar Disorder or Schizophrenia	0.2	0.6	2.3	-0.8	-0.4	-0.4	0.5	-1.0	-0.6	-0.4	0.5	-1.0	-0.6	0.4	-0.7	-0.6	-1.3	-1.5	-0.6	-0.7	-0.2
Schizophrenia (2018)	0.2	0.3	1.2	-0.3	-0.5	-0.3	-0.1	-0.2	-0.4	-0.1	-0.2	-0.6	-0.8	-0.0	-0.6	-1.1	-0.0	-0.7	-0.7	-1.1	0.0
Bipolar Disorder (2011)	0.2	0.2	2.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	-0.5	0.4	1.4	1.1
Fasting Glucose	0.2	0.3	1.3	1.1	-0.6	0.2	0.0	0.5	-0.2	-0.6	-0.4	0.2	0.3	-0.4	0.2	-0.2	0.2	0.9	-0.6	1.0	-0.1
LDL Cholesterol	0.2	0.3	1.7	-0.1	0.4	0.3	1.0	0.4	-0.0	-0.1	-0.2	0.1	0.5	0.6	0.2	-0.2	-1.3	-0.9	0.5	0.4	0.4
Schizophrenia (2014)	0.2	0.5	3.5	0.1	-0.0	-0.0	0.8	0.5	0.2	0.2	0.9	-0.0	-0.2	1.4	0.0	-0.6	-1.2	-1.9	-0.3	-0.2	-0.0
Triglycerides	0.2	0.3	1.2	0.2	1.1	0.6	0.8	-0.1	-0.6	-0.5	0.1	-0.1	0.3	-0.1	-0.2	0.1	-0.6	-0.1	1.1	0.2	1.0
Blood Platelet Count	0.2	1.9	5.8	1.6	2.2	1.3	-0.7	1.7	1.2	0.0	2.1	1.0	1.4	1.5	1.4	1.5	-2.4	-0.2	1.2	-0.1	-0.5
Heel T-Score	0.2	1.2	7.7	-0.4	-1.3	-0.2	-1.7	0.3	0.1	0.0	0.1	-0.1	-0.4	-0.4	0.1	-1.1	1.8	0.5	-1.5	-2.8	-1.4
Systolic Blood Pressure	0.2	1.2	4.3	-0.3	-0.6	-1.3	-0.1	-2.1	-0.5	-0.1	1.5	-0.4	-0.4	1.0	-0.2	0.2	-1.6	-2.0	-1.6	-0.3	-1.3
Respiratory disease	0.2	0.4	1.9	-0.2	-1.4	-0.4	-0.1	-0.1	-0.1	0.2	-1.2	-0.4	-0.5	-0.5	-0.5	-1.1	0.6	0.1	-0.8	-0.5	-0.1
Lung FVC	0.2	1.0	9.1	0.1	0.4	0.3	1.0	3.0	-0.4	-1.3	0.2	-0.3	-0.1	-1.1	-0.5	0.8	-1.2	0.5	0.6	-0.6	-0.7
Age when periods started (menarche)	0.2	0.6	2.8	-0.6	-0.6	-0.2	0.9	-0.7	0.9	1.1	-0.6	0.2	0.2	-1.2	0.3	-0.6	0.8	1.7	-0.2	0.4	0.0
Serious illness, injury or assault to yourself	0.2	0.3	3.4	-0.3	0.2	-0.1	-0.6	-1.9	-0.0	-0.4	-0.4	-0.2	0.1	-0.5	-0.1	0.1	0.1	0.5	0.0	-0.1	-0.1
Heart attack	0.2	0.3	0.8	0.2	0.1	0.3	-0.8	0.1	0.5	0.2	0.3	0.5	0.5	0.8	0.3	0.9	0.8	-0.5	0.3	0.6	0.2
Falls in the last year	0.2	0.3	1.6	0.6	-0.3	0.4	0.8	0.4	-0.0	-0.4	-0.1	0.5	0.3	-0.3	0.3	-0.4	-1.2	0.5	-0.1	0.5	-0.6
Exposure to tobacco smoke at home	0.2	0.2	0.9	0.1	0.7	0.5	-0.2	0.8	-0.0	-0.5	0.7	-0.1	0.5	-0.1	0.0	0.9	0.0	-0.1	1.0	0.0	0.3
High blood pressure (siblings)	0.2	0.3	1.2	-0.5	0.3	-0.6	-1.1	0.6	-1.0	-0.8	-0.3	-0.8	-0.7	-0.2	-0.8	-0.3	-0.2	0.1	-0.2	0.0	0.3
Wheeze or whistling in the chest in last year	0.2	0.3	2.2	0.2	-0.8	-0.0	0.2	0.0	0.2	0.5	0.7	0.2	0.1	1.5	0.1	0.2	-0.6	-1.0	0.0	0.8	0.7
Chest pain or discomfort	0.2	0.3	1.3	-0.2	0.5	0.0	-0.8	0.6	0.1	0.4	-0.3	0.4	0.4	0.2	0.3	-0.7	-0.3	0.3	0.6	1.1	0.8
Supplements: Vitamin C	0.2	0.3	1.3	0.0	-0.1	0.0	0.6	-0.5	0.2	0.7	-0.7	0.1	-0.2	0.6	-0.0	0.1	1.1	0.2	0.1	0.8	0.8
Arm fat percentage (left)	0.2	1.0	4.0	0.5	-0.4	0.0	0.1	-1.5	-0.3	-2.0	1.5	0.1	0.6	0.4	0.3	1.8	-0.8	-0.6	0.4	0.0	-1.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.4	1.8	0.4	0.6	0.4	0.6	1.3	0.4	0.1	0.3	0.4	0.7	-1.1	0.5	1.0	-0.7	0.4	0.9	0.1	-0.2
Tinnitus: Yes, now most or all of the time	0.2	0.2	0.6	0.6	0.7	-0.3	0.8	0.7	0.1	0.2	-0.1	0.4	0.3	-0.3	0.3	0.6	0.3	0.1	0.0	0.8	-0.2
High cholesterol (Self-reported)	0.2	0.4	1.9	-0.3	-0.8	-1.4	1.0	-0.6	-0.4	-0.5	-0.3	-0.3	-0.4	0.7	-0.4	0.8	1.0	-0.3	-0.6	0.5	-0.4
Commuting to job workplace: Cycle	0.2	0.3	2.6	0.9	-0.2	0.6	0.6	1.6	0.3	0.1	0.0	0.6	-0.3	0.4	0.4	-0.2	-0.2	0.3	0.1	-0.3	-0.1
Heart attack/myocardial infarction (self-reported)	0.2	0.3	0.9	0.4	0.1	0.4	-0.9	0.2	0.7	0.3	0.2	0.6	0.6	0.5	0.4	0.9	0.9	-0.1	0.4	0.7	0.3
Intelligence (Savage-Jansen 2018)	0.1	0.4	1.5	-0.6	-0.3	-0.4	1.2	-0.6	-0.0	0.4	-0.9	-0.4	0.2	-0.5	-0.4	-0.5	1.0	0.6	0.2	0.6	1.0
HDL Cholesterol	0.1	0.2	1.2	-0.5	-0.6	-0.6	-0.1	0.7	0.3	0.4	0.4	-0.0	-0.3	0.4	-0.1	0.0	-0.5	-0.5	-0.6	-1.1	-0.4
Tanning	0.1	1.7	4.2	1.3	1.1	1.0	1.7	0.7	1.2	0.8	2.0	1.5	1.9	0.8	1.7	1.7	-1.9	0.4	0.9	0.9	-0.4
Systolic blood pressure, automated reading	0.1	0.3	1.3	0.1	0.1	-0.2	0.5	-0.8	0.1	-0.1	1.1	0.2	0.2	0.5	0.3	0.5	-1.1	-1.1	-0.5	-0.5	-0.5
Body mass index (BMI)	0.1	0.5	2.4	0.5	-1.2	-0.1	-0.5	-1.0	-0.5	-1.6	0.8	0.1	0.0	-0.1	0.1	1.2	0.1	0.4	-0.0	0.2	-1.2
Had menopause	0.1	0.1	0.4	-0.1	-0.4	0.0	0.0	-0.6	0.1	0.1	-0.4	-0.0	-0.2	-0.4	-0.2	-0.2	0.1	0.3	-0.4	-0.0	0.2
Breastfed as a baby	0.1	0.2	0.5	0.1	0.5	0.2	-0.4	0.4	0.4	0.6	0.1	-0.0	0.7	-0.2	0.3	0.6	0.1	0.5	0.3	0.7	0.3
Age at last live birth	0.1	0.2	0.6	0.2	0.6	0.2	-0.4	-0.7	0.0	-0.0	0.3	0.3	0.1	0.0	0.1	-0.8	-0.5	-0.4	-0.1	-0.4	-0.5
Illnesses of siblings: Diabetes	0.1	0.1	0.4	0.0	-0.1	0.5	-0.3	-0.6	0.7	0.3	-0.2	0.2	0.1	-0.2	0.2	0.1	0.3	-0.3	0.2	-0.1	-0.3
Loneliness, isolation	0.1	0.2	0.9	-0.2	0.1	-0.9	0.8	-0.4	-0.4	0.1	0.2	-0.7	-0.3	0.0	-0.4	0.2	0.6	-0.4	-0.4	0.5	-0.2
Eye problems/disorders: Cataract	0.1	0.1	0.3	0.4	0.3	-0.5	-0.1	0.1	-0.4	-0.4	0.2	-0.0	-0.1	-0.1	0.0	0.0	-0.5	-0.5	-0.5	0.1	-0.2
Medication: Blood pressure	0.1	0.2	0.8	0.1	-0.6	-0.6	-0.9	-0.1	-0.3	0.4	-0.6	-0.1	-0.3	-0.4	-0.1	-0.5	0.8	-0.2	-0.6	0.4	0.1
Medication: Bendroflumethiazide	0.1	0.2	1.4	0.1	-0.1	-0.1	-0.1	-0.5	-0.2	-0.2	-0.1	-0.2	-0.3	0.7	-0.3	-0.2	-0.6	-1.2	-0.0	-0.1	0.0
Ever smoked	0.1	0.2	1.0	-0.3	-0.5	-0.2	-0.5	1.0	-0.7	-0.5	0.3	-0.4	-0.3	0.4	-0.4	0.2	0.5	-0.6	-0.2	0.0	0.0
Blood Red Count	0.0	0.3	1.1	0.4	-0.6	-0.4	0.6	-1.1	0.2	0.6	-0.5	0.8	-0.3	0.3	0.4	-0.4	0.3	-0.6	-0.4	0.5	0.3
Hair Pigment	0.0	0.6	2.2	0.4	1.5	0.6	0.1	0.6	1.1	0.7	0.6	0.6	1.4	-0.1	1.0	0.8	-0.2	0.1	0.9	0.9	-0.3
Diastolic blood pressure, automated reading	0.0	0.1	0.8	0.9	-0.4	0.4	-0.1	0.2	-0.5	-0.5	0.5	0.3	-0.1	0.4	-0.0	-0.1	-0.3	0.0	-0.3	0.2	0.1

Hub : Genes

MAPK9

Models

Trait associations