[Hub]/) : Traits : Arm fat percentage (left) :

chr1:106,906,072-108,296,508

Best TWAS P=5.37e-08 · Best GWAS P=2.5e-07 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex PRMT6 0.19 0.16 lasso 6 0.16 5.4e-19 5.2 -5.1 2.8e-07 -0.99 0.01 0.99 FALSE
2 GTEx Colon Transverse PRMT6 0.29 0.24 lasso 7 0.19 1.4e-09 5.0 -5.2 2.3e-07 -0.96 0.01 0.99 FALSE
3 GTEx Heart Left Ventricle PRMT6 0.16 0.12 enet 9 0.13 2.3e-07 4.9 -5.2 1.7e-07 -0.88 0.01 0.98 FALSE
4 GTEx Liver PRMT6 0.60 0.52 lasso 6 0.58 1.0e-19 5.0 -5.3 1.0e-07 -0.99 0.01 0.99 FALSE
5 GTEx Muscle Skeletal PRMT6 0.32 0.16 enet 13 0.16 2.8e-15 5.0 -5.4 5.7e-08 -0.94 0.01 0.99 FALSE
6 GTEx Thyroid PRMT6 0.19 0.17 enet 14 0.19 1.7e-14 5.0 -5.4 5.4e-08 -0.97 0.01 0.99 TRUE
7 The Cancer Genome Atlas Bladder Urothelial Carcinoma PRMT6 0.13 0.10 lasso 4 0.10 2.0e-08 5.0 -5.1 2.9e-07 -0.97 0.01 0.99 FALSE
8 The Cancer Genome Atlas Esophageal Carcinoma PRMT6 0.33 0.26 lasso 3 0.25 2.0e-08 5.0 -5.1 2.7e-07 -0.97 0.01 0.99 FALSE
9 The Cancer Genome Atlas Lung Squamous Cell Carcinoma PRMT6 0.11 0.12 enet 7 0.12 2.3e-13 5.0 -5.2 2.3e-07 -0.96 0.01 0.99 FALSE
10 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma PRMT6 0.09 0.08 blup 36 0.08 3.3e-06 5.0 -5.3 8.9e-08 -0.94 0.01 0.99 FALSE