Best TWAS P=2.72e-08 · Best GWAS P=1.8e-07 conditioned to 0.000476
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | GSTM1 | 0.51 | 0.05 | blup | 434 | 0.26 | 1.4e-33 | -1.2 | 5.6 | 2.7e-08 | 0.35 | 0.74 | 0.04 | TRUE |
| 2 | YFS | Blood | GNAI3 | 0.43 | 0.44 | lasso | 11 | 0.50 | 2.3e-192 | 5.2 | -5.2 | 2.6e-07 | -0.95 | 0.00 | 0.99 | FALSE |