Best TWAS P=1.39e-09 · Best GWAS P=3.15e-14 conditioned to 0.00756
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | BTBD7 | 0.16 | 0.01 | lasso | 8 | 0.04 | 3.6e-04 | -6.0 | 5.7 | 1.4e-08 | -0.58 | 0.10 | 0.88 | FALSE |
| 2 | The Cancer Genome Atlas | Brain Lower Grade Glioma | C14orf142 | 0.11 | 0.04 | enet | 7 | 0.05 | 7.2e-07 | 4.0 | -5.6 | 1.9e-08 | 0.22 | 0.51 | 0.08 | TRUE |
| 3 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | BTBD7 | 0.02 | 0.01 | blup | 72 | 0.02 | 6.8e-03 | -6.4 | 6.1 | 1.4e-09 | -0.80 | 0.01 | 0.90 | TRUE |
| 4 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | BTBD7 | 0.11 | 0.03 | blup | 72 | 0.02 | 8.0e-02 | -6.0 | 5.6 | 1.9e-08 | -0.56 | 0.03 | 0.68 | FALSE |