[Hub]/) : Traits : Arm fat percentage (left) : ← →

chr14:102,544,860-104,892,153

Best TWAS P=7.9e-11 · Best GWAS P=5.87e-11 conditioned to 0.000103

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	KLC1	0.05	0.03	lasso	3	0.03	1.8e-03	4.4	5.9	3.5e-09	-0.02	0.10	0.67	FALSE
2	GTEx	Adipose Subcutaneous	APOPT1	0.06	0.02	lasso	5	0.02	8.2e-03	4.9	-5.4	8.2e-08	0.03	0.18	0.58	FALSE
3	GTEx	Adipose Visceral Omentum	KLC1	0.06	0.02	lasso	2	0.00	2.2e-01	-5.1	5.3	1.0e-07	0.00	0.09	0.45	FALSE
4	GTEx	Adrenal Gland	KLC1	0.15	0.03	lasso	3	0.06	4.6e-03	4.9	5.9	3.8e-09	-0.03	0.08	0.54	FALSE
5	GTEx	Artery Aorta	KLC1	0.10	0.14	lasso	3	0.14	6.1e-08	-5.0	5.5	3.6e-08	0.00	0.13	0.86	FALSE
6	GTEx	Artery Tibial	TRMT61A	0.07	0.07	lasso	3	0.06	2.4e-05	-5.4	-5.3	9.5e-08	0.03	0.04	0.95	FALSE
7	GTEx	Brain Frontal Cortex BA9	APOPT1	0.17	0.07	lasso	3	0.08	4.6e-03	5.4	-6.1	1.3e-09	0.02	0.04	0.78	FALSE
8	GTEx	Breast Mammary Tissue	MARK3	0.12	0.11	lasso	2	0.08	3.9e-05	-5.2	-5.2	2.0e-07	0.02	0.06	0.90	FALSE
9	GTEx	Breast Mammary Tissue	KLC1	0.12	0.02	enet	26	0.07	2.9e-04	3.8	5.7	1.1e-08	0.00	0.34	0.61	FALSE
10	GTEx	Cells Transformed fibroblasts	KLC1	0.16	0.11	enet	17	0.10	3.1e-08	4.9	5.3	1.2e-07	-0.03	0.22	0.77	FALSE
11	GTEx	Cells Transformed fibroblasts	APOPT1	0.14	0.12	lasso	3	0.10	6.4e-08	-5.1	-5.5	4.3e-08	0.00	0.12	0.88	FALSE
12	GTEx	Colon Transverse	KLC1	0.16	0.01	lasso	7	0.00	1.9e-01	4.6	5.3	1.5e-07	-0.02	0.08	0.52	FALSE
13	GTEx	Esophagus Muscularis	KLC1	0.07	0.01	enet	10	0.02	2.6e-02	-5.1	5.1	2.7e-07	-0.04	0.09	0.57	FALSE
14	GTEx	Lung	MARK3	0.06	0.02	lasso	3	0.01	6.6e-02	-5.2	-5.3	9.0e-08	0.02	0.05	0.88	FALSE
15	GTEx	Lung	CKB	0.07	0.01	lasso	2	0.01	3.4e-02	-5.1	-5.6	1.7e-08	0.01	0.05	0.85	FALSE
16	GTEx	Muscle Skeletal	ZFYVE21	0.10	0.05	lasso	2	0.03	3.3e-04	-5.1	5.2	1.5e-07	-0.02	0.12	0.82	FALSE
17	GTEx	Muscle Skeletal	KLC1	0.11	0.07	lasso	7	0.08	3.3e-08	-5.0	5.5	3.4e-08	-0.02	0.13	0.87	FALSE
18	GTEx	Muscle Skeletal	APOPT1	0.14	0.21	enet	10	0.22	6.7e-21	-5.1	5.8	5.8e-09	-0.02	0.04	0.96	FALSE
19	GTEx	Pituitary	MARK3	0.21	0.27	enet	8	0.25	4.9e-07	-5.2	-5.5	4.8e-08	0.02	0.06	0.90	FALSE
20	GTEx	Prostate	MARK3	0.18	0.22	enet	11	0.20	8.0e-06	-5.2	-5.4	8.7e-08	0.03	0.06	0.88	FALSE
21	GTEx	Skin Sun Exposed Lower leg	MARK3	0.10	0.09	enet	13	0.08	7.5e-07	-5.3	-5.9	3.9e-09	0.02	0.06	0.94	FALSE
22	GTEx	Spleen	KLC1	0.15	0.05	lasso	3	0.03	6.4e-02	5.4	6.0	2.5e-09	-0.03	0.05	0.53	FALSE
23	GTEx	Stomach	MARK3	0.10	0.09	lasso	2	0.04	4.5e-03	-5.2	-5.3	1.2e-07	0.02	0.06	0.84	FALSE
24	GTEx	Stomach	TRMT61A	0.12	0.11	lasso	5	0.08	1.2e-04	-5.2	-5.2	1.9e-07	0.02	0.06	0.90	FALSE
25	GTEx	Thyroid	MARK3	0.38	0.48	lasso	4	0.48	2.8e-41	-5.2	-5.2	1.9e-07	0.02	0.08	0.92	FALSE
26	METSIM	Adipose	MARK3	0.03	0.02	lasso	6	0.03	6.3e-05	4.9	-6.0	1.9e-09	0.04	0.06	0.94	FALSE
27	METSIM	Adipose	TRAF3	0.04	0.02	enet	7	0.04	4.5e-06	5.2	5.5	3.1e-08	0.79	0.03	0.96	TRUE
28	The Cancer Genome Atlas	Breast Invasive Carcinoma	C14orf153	0.05	0.02	lasso	4	0.02	8.0e-05	-5.1	-5.5	3.2e-08	0.03	0.01	0.98	FALSE
29	The Cancer Genome Atlas	Glioblastoma Multiforme	C14orf153	0.14	0.01	blup	40	0.03	3.5e-02	-5.1	-6.1	1.3e-09	0.02	0.01	0.46	FALSE
30	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	MARK3	0.07	0.03	blup	64	0.06	5.5e-07	-4.1	-5.5	4.5e-08	0.03	0.04	0.95	FALSE
31	The Cancer Genome Atlas	Brain Lower Grade Glioma	C14orf153	0.04	0.01	blup	38	0.03	6.2e-04	4.4	-6.2	6.3e-10	0.03	0.03	0.68	FALSE
32	The Cancer Genome Atlas	Lung Adenocarcinoma	C14orf153	0.06	0.02	blup	38	0.04	2.4e-05	-5.1	-6.4	1.7e-10	0.03	0.03	0.88	FALSE
33	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	CKB	0.03	0.00	blup	34	0.02	1.4e-03	4.9	-6.5	7.9e-11	0.03	0.02	0.66	TRUE
34	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	BAG5	0.08	0.09	lasso	2	0.08	3.7e-04	-5.2	-5.2	1.6e-07	0.02	0.01	0.90	FALSE
35	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	C14orf153	0.11	0.11	lasso	3	0.10	1.1e-04	-5.4	-5.8	6.6e-09	0.03	0.01	0.96	FALSE
36	The Cancer Genome Atlas	Prostate Adenocarcinoma	C14orf153	0.09	0.08	blup	38	0.09	6.2e-10	-5.4	-6.3	2.2e-10	0.04	0.01	0.99	FALSE
37	The Cancer Genome Atlas	Prostate Adenocarcinoma	CKB	0.07	0.09	blup	32	0.10	1.1e-10	5.4	-6.1	9.5e-10	0.02	0.01	0.99	FALSE
38	The Cancer Genome Atlas	Stomach Adenocarcinoma	C14orf153	0.20	0.05	lasso	2	0.04	8.8e-04	5.4	-5.6	2.2e-08	0.02	0.01	0.85	FALSE
39	The Cancer Genome Atlas	Thyroid Carcinoma	KLC1	0.04	0.01	blup	82	0.03	5.4e-04	4.6	5.5	3.5e-08	-0.03	0.04	0.73	FALSE