Best TWAS P=2.91e-08 · Best GWAS P=3.14e-09 conditioned to 2.29e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Visceral Omentum | CEP192 | 0.38 | 0.35 | lasso | 4 | 0.43 | 3.0e-24 | -4.1 | -5.2 | 2.5e-07 | -0.36 | 0.96 | 0.04 | FALSE |
| 2 | GTEx | Brain Hippocampus | CEP192 | 0.43 | 0.35 | lasso | 9 | 0.44 | 9.8e-12 | -4.1 | -5.3 | 1.0e-07 | -0.34 | 0.50 | 0.49 | FALSE |
| 3 | GTEx | Brain Nucleus accumbens basal ganglia | PTPN2 | 0.32 | 0.02 | lasso | 10 | 0.05 | 2.2e-02 | 5.1 | 5.5 | 2.9e-08 | 0.24 | 0.09 | 0.18 | TRUE |
| 4 | GTEx | Pituitary | CEP192 | 0.51 | 0.24 | enet | 29 | 0.39 | 1.0e-10 | -4.1 | -5.1 | 3.0e-07 | -0.31 | 0.50 | 0.48 | FALSE |