Best TWAS P=5.15e-11 · Best GWAS P=7.28e-08 conditioned to 0.0594
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | SLC26A1 | 0.12 | 0.06 | bslmm | 400 | 0.08 | 8.0e-10 | 4.6 | 5.8 | 6.3e-09 | 0.51 | 0.13 | 0.85 | TRUE |
| 2 | GTEx | Artery Tibial | GAK | 0.19 | 0.03 | enet | 29 | 0.10 | 2.4e-08 | -3.5 | 5.6 | 2.7e-08 | 0.59 | 0.01 | 0.99 | FALSE |
| 3 | GTEx | Brain Cerebellum | SLC26A1 | 0.61 | 0.41 | enet | 22 | 0.46 | 2.1e-15 | 4.6 | 5.6 | 2.6e-08 | 0.57 | 0.11 | 0.87 | FALSE |
| 4 | GTEx | Stomach | SLC26A1 | 0.26 | 0.17 | enet | 14 | 0.16 | 4.0e-08 | 4.6 | 5.6 | 2.7e-08 | 0.63 | 0.10 | 0.88 | FALSE |
| 5 | NTR | Blood | PCGF3 | 0.07 | 0.00 | enet | 33 | 0.02 | 7.7e-08 | 4.0 | 5.3 | 8.9e-08 | 0.27 | 0.50 | 0.32 | FALSE |
| 6 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | SLC26A1 | 0.05 | 0.01 | blup | 53 | 0.02 | 1.2e-02 | 3.4 | 5.2 | 2.6e-07 | 0.58 | 0.05 | 0.38 | FALSE |
| 7 | The Cancer Genome Atlas | Breast Invasive Carcinoma | PCGF3 | 0.03 | 0.00 | blup | 69 | 0.01 | 3.7e-03 | 4.0 | 6.6 | 5.2e-11 | 0.34 | 0.00 | 0.13 | TRUE |