Best TWAS P=5.78e-09 · Best GWAS P=6.38e-14 conditioned to 3.27e-12
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | DCAF16 | 0.10 | 0.01 | enet | 6 | 0.02 | 4.7e-02 | 4.4 | -5.2 | 1.6e-07 | -0.02 | 0.16 | 0.34 | FALSE |
| 2 | GTEx | Breast Mammary Tissue (Male) | DCAF16 | 0.24 | 0.03 | enet | 18 | -0.01 | 4.4e-01 | 4.6 | -5.8 | 5.8e-09 | -0.10 | 0.04 | 0.57 | TRUE |
| 3 | GTEx | Spleen | DCAF16 | 0.35 | 0.02 | lasso | 5 | 0.11 | 8.5e-04 | -4.1 | -5.6 | 2.5e-08 | 0.04 | 0.07 | 0.42 | FALSE |
| 4 | GTEx | Thyroid | DCAF16 | 0.11 | 0.02 | lasso | 5 | 0.03 | 2.3e-03 | -4.1 | -5.2 | 1.8e-07 | 0.01 | 0.21 | 0.62 | FALSE |
| 5 | The Cancer Genome Atlas | Brain Lower Grade Glioma | DCAF16 | 0.09 | 0.02 | lasso | 3 | 0.04 | 5.2e-05 | -4.1 | -5.4 | 7.2e-08 | -0.02 | 0.23 | 0.38 | FALSE |
| 6 | The Cancer Genome Atlas | Prostate Adenocarcinoma | DCAF16 | 0.04 | 0.04 | blup | 31 | 0.04 | 2.2e-05 | -4.1 | -5.7 | 1.6e-08 | -0.05 | 0.20 | 0.40 | FALSE |
| 7 | The Cancer Genome Atlas | Thyroid Carcinoma | DCAF16 | 0.07 | 0.04 | blup | 31 | 0.07 | 4.9e-07 | -4.3 | -5.2 | 2.0e-07 | 0.00 | 0.35 | 0.42 | FALSE |