Best TWAS P=1.03e-07 · Best GWAS P=1.37e-10 conditioned to 1.49e-08
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | FAM114A2 | 0.28 | 0.39 | lasso | 9 | 0.41 | 1.8e-53 | -5.0 | 5.2 | 2.3e-07 | 0.22 | 0.92 | 0.08 | FALSE |
2 | NTR | Blood | FAM114A2 | 0.04 | 0.03 | lasso | 10 | 0.02 | 8.9e-08 | -5.0 | 5.2 | 1.9e-07 | 0.18 | 0.92 | 0.08 | FALSE |
3 | ROSMAP | Brain Pre-frontal Cortex | FAM114A2 | 0.05 | 0.06 | lasso | 6 | 0.05 | 6.3e-07 | -5.1 | 5.1 | 3.1e-07 | 0.29 | 0.90 | 0.09 | FALSE |
4 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | FAM114A2 | 0.07 | 0.06 | blup | 56 | 0.06 | 1.5e-03 | -4.9 | -5.3 | 1.0e-07 | -0.15 | 0.02 | 0.66 | TRUE |