Best TWAS P=7.46e-15 · Best GWAS P=5.77e-16 conditioned to 6.92e-07
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Muscularis | NEGR1 | 0.13 | 0.04 | lasso | 3 | 0.05 | 5.1e-04 | -4.6 | 5.6 | 2.7e-08 | -0.66 | 0.65 | 0.20 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | NEGR1 | 0.24 | 0.15 | lasso | 8 | 0.22 | 1.3e-27 | 5.2 | 7.8 | 7.5e-15 | -0.48 | 0.09 | 0.91 | TRUE |