Best TWAS P=4.74e-09 · Best GWAS P=5.91e-11 conditioned to 0.00255
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | STK33 | 0.18 | 0.18 | lasso | 9 | 0.2 | 3.8e-24 | -5.0 | 5.9 | 4.7e-09 | -0.83 | 0.84 | 0.16 | TRUE |
2 | The Cancer Genome Atlas | Thyroid Carcinoma | STK33 | 0.14 | 0.08 | lasso | 6 | 0.1 | 1.0e-09 | -5.3 | 5.8 | 7.3e-09 | -0.66 | 0.52 | 0.48 | FALSE |