[Hub]/) : Traits : Arm fat mass (left) :

chr1:752,566-3,191,909

Best TWAS P=1.57e-11 · Best GWAS P=4.63e-09 conditioned to 0.0515

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous RP1-283E3.4 0.65 0.14 lasso 9 0.33 5.1e-28 -3.3 -5.9 4.3e-09 0.00 0.83 0.04 FALSE
2 GTEx Adipose Visceral Omentum RP1-283E3.4 0.26 0.05 enet 25 0.16 1.5e-08 -3.3 -5.8 5.9e-09 -0.02 0.13 0.08 FALSE
3 GTEx Artery Aorta RP1-283E3.4 0.60 0.12 lasso 9 0.27 3.2e-15 -3.3 -5.3 9.0e-08 -0.01 0.45 0.09 FALSE
4 GTEx Artery Tibial RP1-283E3.4 0.66 0.09 lasso 6 0.38 4.9e-31 -3.3 -5.5 3.9e-08 0.01 0.83 0.04 FALSE
5 GTEx Artery Tibial RP11-345P4.10 0.61 0.10 lasso 10 0.36 3.1e-29 -3.0 5.2 1.7e-07 0.01 0.85 0.02 FALSE
6 GTEx Brain Cerebellar Hemisphere RP5-890O3.9 0.24 0.02 lasso 9 0.02 1.3e-01 -4.9 5.4 5.4e-08 -0.01 0.02 0.49 TRUE
7 GTEx Cells Transformed fibroblasts RP1-283E3.4 0.59 0.13 lasso 8 0.29 3.0e-22 3.2 -6.1 1.1e-09 0.01 0.84 0.03 FALSE
8 GTEx Cells Transformed fibroblasts RP11-345P4.10 0.66 0.17 lasso 13 0.32 7.5e-25 -3.0 5.1 3.0e-07 0.00 0.85 0.02 FALSE
9 GTEx Esophagus Mucosa RP1-283E3.4 0.53 0.12 enet 20 0.22 4.1e-15 -3.3 -6.5 9.6e-11 0.02 0.82 0.04 FALSE
10 GTEx Esophagus Muscularis RP1-283E3.4 0.46 0.14 enet 23 0.24 1.6e-14 -3.3 -6.7 1.6e-11 0.01 0.79 0.04 TRUE
11 GTEx Esophagus Muscularis RP3-395M20.12 0.08 0.06 enet 6 0.06 2.3e-04 4.4 -5.8 6.7e-09 0.78 0.01 0.98 TRUE
12 GTEx Heart Atrial Appendage RP11-345P4.10 0.36 0.11 enet 15 0.16 1.1e-07 -3.0 5.3 8.8e-08 -0.01 0.08 0.05 FALSE
13 GTEx Lung RP1-283E3.4 0.58 0.07 lasso 7 0.34 8.8e-27 -3.3 -5.5 2.9e-08 0.02 0.83 0.03 FALSE
14 GTEx Muscle Skeletal TMEM52 0.11 0.08 lasso 6 0.10 7.2e-10 -4.9 5.4 6.2e-08 -0.02 0.03 0.96 FALSE
15 GTEx Muscle Skeletal SLC35E2B 0.35 0.06 lasso 4 0.19 3.2e-18 -3.0 5.7 1.4e-08 0.01 0.83 0.02 FALSE
16 GTEx Muscle Skeletal RP1-283E3.4 0.51 0.12 lasso 6 0.29 2.4e-28 -3.3 -5.4 5.4e-08 0.01 0.83 0.04 FALSE
17 GTEx Muscle Skeletal RP11-345P4.10 0.54 0.06 lasso 7 0.29 4.7e-29 -3.0 5.5 4.0e-08 0.00 0.84 0.02 FALSE
18 GTEx Pancreas TNFRSF14 0.13 0.04 enet 8 0.04 1.0e-02 4.4 5.2 2.6e-07 -0.63 0.17 0.72 FALSE
19 GTEx Skin Not Sun Exposed Suprapubic RP1-283E3.4 0.48 0.12 lasso 5 0.31 1.1e-17 -3.3 -6.0 2.0e-09 0.01 0.39 0.11 FALSE
20 GTEx Thyroid RP1-283E3.4 0.59 0.04 lasso 10 0.22 3.8e-17 -3.3 -6.2 6.9e-10 0.00 0.62 0.05 FALSE
21 The Cancer Genome Atlas Testicular Germ Cell Tumors TNFRSF14 0.18 0.02 blup 52 0.10 2.4e-04 2.7 5.2 1.6e-07 -0.68 0.01 0.46 FALSE