Best TWAS P=8.21e-11 · Best GWAS P=8.37e-12 conditioned to 0.000568
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Muscularis | GRB14 | 0.14 | 0.09 | lasso | 7 | 0.06 | 0.00016 | 6.3 | -6.5 | 8.2e-11 | -0.65 | 0.04 | 0.92 | TRUE |
| 2 | The Cancer Genome Atlas | Colon Adenocarcinoma | GRB14 | 0.09 | 0.01 | blup | 82 | 0.03 | 0.00464 | 5.2 | -5.5 | 5.0e-08 | -0.57 | 0.02 | 0.65 | FALSE |