[Hub]/) : Traits : Arm fat mass (left) :

chr3:182,655,858-184,700,426

Best TWAS P=4.32e-10 · Best GWAS P=1.4e-08 conditioned to 0.0279

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex ECE2 0.24 0.20 bslmm 542 0.19 1.6e-22 5.7 5.3 1.0e-07 0.98 0.00 0.99 FALSE
2 CommonMind Brain Pre-frontal Cortex KLHL24 0.42 0.60 bslmm 493 0.66 4.5e-107 -5.6 -5.6 2.4e-08 -0.14 0.02 0.98 FALSE
3 GTEx Adipose Subcutaneous KLHL24 0.15 0.10 lasso 6 0.10 1.4e-08 -5.6 6.0 1.9e-09 0.17 0.02 0.98 TRUE
4 GTEx Brain Caudate basal ganglia KLHL24 0.22 0.21 lasso 3 0.19 3.5e-06 -5.6 5.6 1.9e-08 0.16 0.02 0.96 FALSE
5 GTEx Brain Cerebellar Hemisphere KLHL24 0.31 0.10 enet 22 0.09 3.4e-03 -5.6 5.2 1.5e-07 0.06 0.02 0.92 FALSE
6 GTEx Brain Cerebellum KLHL24 0.52 0.14 enet 26 0.16 1.9e-05 -5.6 5.6 2.5e-08 0.15 0.02 0.97 FALSE
7 GTEx Brain Cortex KLHL24 0.21 0.15 lasso 3 0.07 6.1e-03 -5.6 6.0 2.3e-09 0.18 0.02 0.93 FALSE
8 GTEx Brain Frontal Cortex BA9 KLHL24 0.36 0.23 lasso 6 0.15 9.3e-05 -5.6 5.2 2.2e-07 0.15 0.02 0.96 FALSE
9 GTEx Breast Mammary Tissue KLHL24 0.25 0.13 lasso 5 0.11 3.4e-06 -5.6 5.7 1.5e-08 0.17 0.02 0.98 FALSE
10 GTEx Esophagus Muscularis KLHL24 0.10 0.12 lasso 1 0.09 4.4e-06 -5.6 5.6 1.9e-08 0.16 0.02 0.98 FALSE
11 GTEx Nerve Tibial KLHL24 0.08 0.06 lasso 3 0.05 1.5e-04 -5.6 5.5 3.0e-08 0.15 0.03 0.96 FALSE
12 GTEx Pituitary ECE2 0.52 0.30 lasso 7 0.23 1.5e-06 5.7 5.8 6.0e-09 0.91 0.01 0.99 FALSE
13 GTEx Skin Sun Exposed Lower leg KLHL24 0.09 0.06 lasso 10 0.05 9.5e-05 -5.6 5.6 2.2e-08 0.16 0.02 0.97 FALSE
14 GTEx Testis KLHL24 0.17 0.10 lasso 4 0.10 4.0e-05 -5.6 5.6 1.9e-08 0.16 0.02 0.98 FALSE
15 METSIM Adipose MAP6D1 0.06 0.05 bslmm 473 0.06 2.3e-09 5.1 5.6 2.0e-08 0.25 0.68 0.31 FALSE
16 The Cancer Genome Atlas Brain Lower Grade Glioma ECE2 0.04 0.02 blup 61 0.03 3.5e-04 5.7 6.2 4.3e-10 0.89 0.00 0.99 TRUE
17 The Cancer Genome Atlas Brain Lower Grade Glioma KLHL24 0.05 0.05 blup 53 0.05 1.1e-06 -5.6 5.5 4.5e-08 0.15 0.02 0.98 FALSE
18 The Cancer Genome Atlas Lung Adenocarcinoma PSMD2 0.09 0.02 blup 50 0.05 1.2e-06 -2.9 5.6 2.7e-08 0.57 0.07 0.62 FALSE
19 The Cancer Genome Atlas Testicular Germ Cell Tumors KLHL24 0.16 0.16 blup 53 0.21 4.3e-08 -5.6 5.3 1.5e-07 0.14 0.02 0.98 FALSE