[Hub]/) : Traits : Arm fat mass (left) : ← →

chr3:182,655,858-184,700,426

Best TWAS P=4.32e-10 · Best GWAS P=1.4e-08 conditioned to 0.0279

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
16	The Cancer Genome Atlas	Brain Lower Grade Glioma	ECE2	0.04	0.02	blup	61	0.03	3.5e-04	5.7	6.2	4.3e-10	0.89	0.00	0.99	TRUE
3	GTEx	Adipose Subcutaneous	KLHL24	0.15	0.10	lasso	6	0.10	1.4e-08	-5.6	6.0	1.9e-09	0.17	0.02	0.98	TRUE
7	GTEx	Brain Cortex	KLHL24	0.21	0.15	lasso	3	0.07	6.1e-03	-5.6	6.0	2.3e-09	0.18	0.02	0.93	FALSE
12	GTEx	Pituitary	ECE2	0.52	0.30	lasso	7	0.23	1.5e-06	5.7	5.8	6.0e-09	0.91	0.01	0.99	FALSE
9	GTEx	Breast Mammary Tissue	KLHL24	0.25	0.13	lasso	5	0.11	3.4e-06	-5.6	5.7	1.5e-08	0.17	0.02	0.98	FALSE
4	GTEx	Brain Caudate basal ganglia	KLHL24	0.22	0.21	lasso	3	0.19	3.5e-06	-5.6	5.6	1.9e-08	0.16	0.02	0.96	FALSE
10	GTEx	Esophagus Muscularis	KLHL24	0.10	0.12	lasso	1	0.09	4.4e-06	-5.6	5.6	1.9e-08	0.16	0.02	0.98	FALSE
14	GTEx	Testis	KLHL24	0.17	0.10	lasso	4	0.10	4.0e-05	-5.6	5.6	1.9e-08	0.16	0.02	0.98	FALSE
15	METSIM	Adipose	MAP6D1	0.06	0.05	bslmm	473	0.06	2.3e-09	5.1	5.6	2.0e-08	0.25	0.68	0.31	FALSE
13	GTEx	Skin Sun Exposed Lower leg	KLHL24	0.09	0.06	lasso	10	0.05	9.5e-05	-5.6	5.6	2.2e-08	0.16	0.02	0.97	FALSE
2	CommonMind	Brain Pre-frontal Cortex	KLHL24	0.42	0.60	bslmm	493	0.66	4.5e-107	-5.6	-5.6	2.4e-08	-0.14	0.02	0.98	FALSE
6	GTEx	Brain Cerebellum	KLHL24	0.52	0.14	enet	26	0.16	1.9e-05	-5.6	5.6	2.5e-08	0.15	0.02	0.97	FALSE
18	The Cancer Genome Atlas	Lung Adenocarcinoma	PSMD2	0.09	0.02	blup	50	0.05	1.2e-06	-2.9	5.6	2.7e-08	0.57	0.07	0.62	FALSE
11	GTEx	Nerve Tibial	KLHL24	0.08	0.06	lasso	3	0.05	1.5e-04	-5.6	5.5	3.0e-08	0.15	0.03	0.96	FALSE
17	The Cancer Genome Atlas	Brain Lower Grade Glioma	KLHL24	0.05	0.05	blup	53	0.05	1.1e-06	-5.6	5.5	4.5e-08	0.15	0.02	0.98	FALSE
1	CommonMind	Brain Pre-frontal Cortex	ECE2	0.24	0.20	bslmm	542	0.19	1.6e-22	5.7	5.3	1.0e-07	0.98	0.00	0.99	FALSE
5	GTEx	Brain Cerebellar Hemisphere	KLHL24	0.31	0.10	enet	22	0.09	3.4e-03	-5.6	5.2	1.5e-07	0.06	0.02	0.92	FALSE
19	The Cancer Genome Atlas	Testicular Germ Cell Tumors	KLHL24	0.16	0.16	blup	53	0.21	4.3e-08	-5.6	5.3	1.5e-07	0.14	0.02	0.98	FALSE
8	GTEx	Brain Frontal Cortex BA9	KLHL24	0.36	0.23	lasso	6	0.15	9.3e-05	-5.6	5.2	2.2e-07	0.15	0.02	0.96	FALSE