Best TWAS P=5.43e-19 · Best GWAS P=1.33e-19 conditioned to 9.11e-07
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Gastroesophageal Junction | TMEM161B-AS1 | 0.19 | 0.09 | lasso | 6 | 0.09 | 4.2e-04 | 4.0 | 6.0 | 2.2e-09 | 0.36 | 0.26 | 0.21 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | LINC00461 | 0.10 | 0.07 | lasso | 2 | 0.05 | 4.5e-07 | 8.9 | 8.9 | 5.4e-19 | 0.95 | 0.00 | 1.00 | TRUE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | CTC-498M16.2 | 0.11 | 0.13 | lasso | 6 | 0.12 | 1.2e-14 | -7.4 | -6.5 | 8.8e-11 | 0.13 | 1.00 | 0.00 | TRUE |