Best TWAS P=1.04e-08 · Best GWAS P=5.31e-11 conditioned to 2.87e-07
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | FAM114A2 | 0.28 | 0.39 | lasso | 9 | 0.41 | 1.8e-53 | -4.9 | 5.2 | 1.5e-07 | 0.22 | 0.98 | 0.02 | FALSE |
2 | NTR | Blood | FAM114A2 | 0.04 | 0.03 | lasso | 10 | 0.02 | 8.9e-08 | -4.9 | 5.1 | 3.0e-07 | 0.18 | 0.98 | 0.02 | FALSE |
3 | ROSMAP | Brain Pre-frontal Cortex | FAM114A2 | 0.05 | 0.06 | lasso | 6 | 0.05 | 6.3e-07 | -5.7 | 5.7 | 1.0e-08 | 0.29 | 0.60 | 0.39 | TRUE |