Best TWAS P=6.3e-10 · Best GWAS P=4.16e-10 conditioned to 0.00739
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | RP11-179B2.2 | 0.16 | 0.11 | lasso | 2 | 0.09 | 7.6e-06 | 5.4 | 5.4 | 8.5e-08 | 0.73 | 0.13 | 0.82 | FALSE |
| 2 | GTEx | Brain Cerebellum | RP11-179B2.2 | 0.37 | 0.21 | lasso | 4 | 0.20 | 1.4e-06 | 5.4 | 6.2 | 6.3e-10 | 0.70 | 0.15 | 0.68 | TRUE |
| 3 | GTEx | Esophagus Muscularis | RP11-179B2.2 | 0.15 | 0.16 | lasso | 3 | 0.16 | 8.1e-10 | 5.2 | 5.2 | 2.3e-07 | 0.71 | 0.26 | 0.74 | FALSE |
| 4 | GTEx | Heart Left Ventricle | RP11-179B2.2 | 0.15 | 0.18 | enet | 2 | 0.14 | 4.8e-08 | 5.4 | 5.4 | 6.4e-08 | 0.74 | 0.13 | 0.87 | FALSE |