TWAS
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About
Usage
Models
Genes
Traits
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Traits
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Arm fat mass (left)
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chr11:7,714,238-9,313,814
Best TWAS P=1.99e-08 · Best GWAS P=5.78e-12 conditioned to 6.46e-05
7.8M
8M
8.2M
8.4M
8.6M
8.8M
9M
9.2M
9.4M
0
2
4
6
8
10
12
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
CommonMind
Brain Pre-frontal Cortex
STK33
0.18
0.18
lasso
9
0.20
3.8e-24
-4.9
5.6
2.0e-08
-0.83
0.92
0.08
TRUE
4
The Cancer Genome Atlas
Thyroid Carcinoma
STK33
0.14
0.08
lasso
6
0.10
1.0e-09
-4.9
5.4
6.6e-08
-0.66
0.98
0.02
FALSE
2
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
STK33
0.05
0.03
lasso
2
0.03
2.5e-04
-5.4
5.2
2.5e-07
-0.53
0.48
0.11
FALSE
3
The Cancer Genome Atlas
Testicular Germ Cell Tumors
ST5
0.41
0.02
blup
128
0.13
2.3e-05
3.1
-5.2
2.5e-07
0.58
0.03
0.61
FALSE