[Hub]/) : Traits : Arm fat-free mass (left) :

chr6:80,120,201-81,872,212

Best TWAS P=5.68e-18 · Best GWAS P=6.1e-14 conditioned to 0.00117

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum RP11-250B2.6 0.16 0.05 lasso 6 0.06 7.8e-04 6.3 -6.7 1.7e-11 -0.57 0.20 0.50 FALSE
2 GTEx Brain Cerebellum RP11-250B2.5 0.43 0.11 lasso 5 0.14 4.7e-05 -6.7 -7.0 3.4e-12 -0.76 0.09 0.80 FALSE
3 GTEx Cells EBV-transformed lymphocytes RP11-250B2.6 0.21 0.03 enet 37 0.13 4.7e-05 4.7 -6.3 2.3e-10 -0.23 0.14 0.09 FALSE
4 GTEx Cells Transformed fibroblasts BCKDHB 0.16 0.02 enet 42 0.04 3.7e-04 4.2 7.4 1.8e-13 0.49 0.27 0.61 FALSE
5 GTEx Esophagus Mucosa RP11-250B2.6 0.20 0.16 lasso 7 0.23 3.3e-15 -6.5 -6.6 5.4e-11 -0.65 0.83 0.17 FALSE
6 GTEx Heart Atrial Appendage RP11-250B2.6 0.20 0.00 enet 17 0.03 2.6e-02 -4.0 -8.6 5.7e-18 -0.41 0.05 0.51 TRUE
7 GTEx Heart Left Ventricle RP11-250B2.6 0.09 0.00 enet 6 0.02 2.0e-02 7.0 -6.5 1.0e-10 -0.82 0.04 0.79 FALSE
8 GTEx Lung RP11-250B2.6 0.09 0.05 enet 16 0.07 5.3e-06 4.3 -6.6 4.4e-11 -0.36 0.69 0.19 TRUE
9 GTEx Muscle Skeletal RP11-250B2.6 0.07 0.04 lasso 5 0.04 4.2e-05 7.3 -7.5 5.9e-14 -0.94 0.02 0.98 FALSE
10 GTEx Testis RP11-250B2.5 0.13 0.17 lasso 3 0.14 7.0e-07 -6.5 -6.4 1.8e-10 -0.88 0.05 0.94 FALSE
11 GTEx Thyroid BCKDHB 0.17 0.06 lasso 8 0.10 3.4e-08 4.3 5.8 7.7e-09 0.46 0.97 0.03 FALSE
12 METSIM Adipose RP11-250B2.6 0.04 0.04 lasso 12 0.02 1.7e-04 6.5 -5.7 1.1e-08 -0.60 0.60 0.20 FALSE
13 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma BCKDHB 0.12 0.06 lasso 4 0.06 4.2e-07 5.8 -5.4 8.0e-08 -0.75 0.31 0.68 FALSE