TWAS
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Traits
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Traits
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Arm fat-free mass (left)
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chr6:85,673,386-87,086,122
Best TWAS P=1.71e-07 · Best GWAS P=1.25e-06 conditioned to 0.00947
85.6M
85.8M
86M
86.2M
86.4M
86.6M
86.8M
87M
0
1
2
3
4
5
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Esophagus Gastroesophageal Junction
SNHG5
0.29
0.34
lasso
3
0.34
7.3e-13
4.2
-5.2
1.7e-07
0.50
0.13
0.79
TRUE
2
The Cancer Genome Atlas
Cervical Squamous Cell Carcinoma
SYNCRIP
0.07
0.04
blup
35
0.03
1.3e-02
4.4
5.1
2.8e-07
-0.33
0.02
0.60
FALSE