Best TWAS P=1.71e-07 · Best GWAS P=1.25e-06 conditioned to 0.00947
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Esophagus Gastroesophageal Junction | SNHG5 | 0.29 | 0.34 | lasso | 3 | 0.34 | 7.3e-13 | 4.2 | -5.2 | 1.7e-07 | 0.50 | 0.13 | 0.79 | TRUE |
2 | The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | SYNCRIP | 0.07 | 0.04 | blup | 35 | 0.03 | 1.3e-02 | 4.4 | 5.1 | 2.8e-07 | -0.33 | 0.02 | 0.60 | FALSE |