TWAS
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Traits
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Traits
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Arm fat-free mass (left)
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chr6:100,712,304-101,576,316
Best TWAS P=1.35e-08 · Best GWAS P=2.4e-09 conditioned to 0.0428
100.7M
100.8M
100.9M
101M
101.1M
101.2M
101.3M
101.4M
101.5M
101.6M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Thyroid Carcinoma
ASCC3
0.06
0.05
lasso
1
0.04
0.0002
5.7
-5.7
1.4e-08
-0.88
0.06
0.93
TRUE
1
The Cancer Genome Atlas
Esophageal Carcinoma
ASCC3
0.11
0.07
blup
131
0.07
0.0024
-4.5
-5.6
2.6e-08
-0.84
0.08
0.69
FALSE