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Arm fat-free mass (left)
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chr7:45,255,940-46,658,015
Best TWAS P=4.15e-08 · Best GWAS P=5.9e-12 conditioned to 2.05e-08
45.2M
45.4M
45.6M
45.8M
46M
46.2M
46.4M
46.6M
0
2
4
6
8
10
12
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Skin Sun Exposed Lower leg
IGFBP3
0.09
0
lasso
6
0
0.27
-4.5
-5.5
4.2e-08
-0.27
0.03
0.75
TRUE