TWAS
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Traits
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Traits
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Arm fat-free mass (left)
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chr7:98,791,892-100,214,015
Best TWAS P=1.04e-07 · Best GWAS P=5.1e-09 conditioned to 0.000106
98.8M
99M
99.2M
99.4M
99.6M
99.8M
100M
100.2M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Skin Not Sun Exposed Suprapubic
TRIM4
0.18
0.09
enet
17
0.13
1.8e-07
4.8
-5.3
1.0e-07
0.45
0.22
0.77
TRUE
3
GTEx
Whole Blood
TRIM4
0.12
0.05
lasso
5
0.06
5.9e-06
4.8
-5.2
2.0e-07
0.47
0.21
0.78
FALSE
4
The Cancer Genome Atlas
Glioblastoma Multiforme
TRIM4
0.23
0.13
blup
52
0.20
1.4e-06
4.8
-5.1
3.0e-07
0.51
0.20
0.76
FALSE
2
GTEx
Skin Sun Exposed Lower leg
TRIM4
0.39
0.26
lasso
11
0.25
5.5e-21
4.8
-5.1
3.1e-07
0.45
0.22
0.78
FALSE