Best TWAS P=1.44e-14 · Best GWAS P=9.33e-17 conditioned to 9.8e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Breast Invasive Carcinoma | GSDMC | 0.05 | 0.06 | lasso | 7 | 0.05 | 1.5e-10 | -5.4 | -6.4 | 1.6e-10 | 0.66 | 0.86 | 0.14 | FALSE |
| 2 | The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | GSDMC | 0.21 | 0.14 | blup | 57 | 0.15 | 1.2e-07 | -5.5 | -7.7 | 1.4e-14 | 0.74 | 0.25 | 0.72 | TRUE |
| 3 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | GSDMC | 0.25 | 0.30 | lasso | 5 | 0.32 | 4.6e-36 | -5.4 | -5.4 | 7.4e-08 | 0.57 | 1.00 | 0.00 | FALSE |
| 4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | GSDMC | 0.03 | 0.02 | blup | 57 | 0.02 | 1.4e-03 | -5.4 | -5.4 | 6.1e-08 | 0.65 | 0.04 | 0.65 | FALSE |