TWAS
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Traits
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Traits
:
Arm fat-free mass (left)
:
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chr8:130,517,157-131,045,893
Best TWAS P=1.44e-14 · Best GWAS P=9.33e-17 conditioned to 9.8e-05
130.5M
130.6M
130.7M
130.8M
130.9M
131M
0
5
10
15
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Cervical Squamous Cell Carcinoma
GSDMC
0.21
0.14
blup
57
0.15
1.2e-07
-5.5
-7.7
1.4e-14
0.74
0.25
0.72
TRUE
1
The Cancer Genome Atlas
Breast Invasive Carcinoma
GSDMC
0.05
0.06
lasso
7
0.05
1.5e-10
-5.4
-6.4
1.6e-10
0.66
0.86
0.14
FALSE
4
The Cancer Genome Atlas
Prostate Adenocarcinoma
GSDMC
0.03
0.02
blup
57
0.02
1.4e-03
-5.4
-5.4
6.1e-08
0.65
0.04
0.65
FALSE
3
The Cancer Genome Atlas
Head and Neck Squamous Cell Carcinoma
GSDMC
0.25
0.30
lasso
5
0.32
4.6e-36
-5.4
-5.4
7.4e-08
0.57
1.00
0.00
FALSE