TWAS hub - GSDMC

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Bladder Urothelial Carcinoma	0.0350	0.0220	9.9e-03	0.006	0.016	0.010	NA	0.009	8.8e-02	1.4e-02	4.3e-02	NA	4.8e-02
2	TCGA	Breast Invasive Carcinoma	0.0533	0.0196	4.1e-10	0.056	0.045	0.045	NA	0.050	1.2e-11	1.4e-09	1.6e-09	NA	1.5e-10
3	TCGA	Cervical Squamous Cell Carcinoma	0.2090	0.0750	2.4e-06	0.143	0.146	0.113	NA	0.129	1.6e-07	1.2e-07	3.6e-06	NA	7.0e-07
4	TCGA	Colon Adenocarcinoma	0.1330	0.0510	2.8e-05	0.080	0.071	0.080	NA	0.093	2.3e-05	6.2e-05	2.3e-05	NA	5.0e-06
5	TCGA	Head and Neck Squamous Cell Carcinoma	0.2512	0.0597	0.0e+00	0.298	0.284	0.314	NA	0.315	9.1e-34	4.5e-32	6.2e-36	NA	4.6e-36
6	TCGA	Lung Adenocarcinoma	0.0905	0.0353	4.0e-06	0.031	0.052	0.063	NA	0.058	1.5e-04	9.4e-07	7.0e-08	NA	2.5e-07
7	TCGA	Lung Squamous Cell Carcinoma	0.1650	0.0532	5.2e-14	0.135	0.152	0.138	NA	0.133	3.9e-15	6.3e-17	2.1e-15	NA	6.3e-15
8	TCGA	Prostate Adenocarcinoma	0.0295	0.0162	3.0e-03	0.017	0.024	0.008	NA	0.016	6.4e-03	1.4e-03	4.5e-02	NA	7.9e-03
9	TCGA	Uterine Corpus Endometrial Carcinoma	0.2080	0.1030	5.5e-03	0.046	0.055	0.010	NA	0.005	2.1e-02	1.2e-02	1.7e-01	NA	2.2e-01

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Standing height	21.2	210.6	301.9	-14.4	-16.1	-17.4	-13.5	-15.3	-12.3	-13.1	-15.9	-11.7
Comparative height size at age 10	20.3	111.6	174.2	-10.1	-11.9	-13.2	-9.4	-11.0	-8.5	-9.5	-11.6	-8.9
Sitting height	20.2	143.6	228.0	-11.4	-13.8	-15.1	-10.8	-12.6	-10.1	-10.7	-13.4	-8.5
Height	19.7	379.9	542.9	-19.1	-22.2	-23.3	-17.9	-20.9	-16.1	-17.6	-21.9	-14.6
Forced vital capacity (FVC), Best measure	17.0	62.3	87.2	-7.7	-8.8	-8.6	-7.3	-8.4	-6.6	-7.5	-9.3	-6.3
Forced vital capacity (FVC)	16.4	63.2	85.7	-8.0	-8.7	-8.2	-7.5	-8.4	-6.8	-7.8	-9.3	-6.6
Forced expiratory volume in 1-second (FEV1), Best measure	15.4	49.1	64.0	-6.7	-7.7	-7.2	-6.8	-7.4	-6.3	-6.7	-8.0	-6.0
Forced expiratory volume in 1-second (FEV1), predicted	15.0	31.1	39.2	-5.8	-6.0	-5.4	-5.2	-6.0	-4.5	-5.4	-6.3	-5.3
Forced expiratory volume in 1-second (FEV1)	14.6	49.3	65.1	-7.0	-7.6	-6.7	-6.8	-7.3	-6.3	-7.0	-8.1	-6.2
Peak expiratory flow (PEF)	13.4	31.0	42.6	-5.3	-6.1	-5.3	-5.7	-6.0	-5.3	-5.3	-6.5	-4.2
Trunk predicted mass	8.3	47.2	91.5	-6.2	-8.2	-9.6	-6.2	-7.1	-6.1	-5.5	-7.1	-4.5
Trunk fat-free mass	8.2	47.3	92.2	-6.2	-8.2	-9.6	-6.2	-7.1	-6.2	-5.5	-7.1	-4.5
Whole body fat-free mass	6.7	38.1	76.0	-5.4	-7.4	-8.7	-5.6	-6.3	-5.7	-4.9	-6.3	-4.0
Arm fat-free mass (right)	6.5	33.3	66.3	-5.2	-6.9	-8.1	-5.3	-6.0	-5.3	-4.4	-5.9	-3.5
Whole body water mass	6.4	36.6	73.8	-5.3	-7.2	-8.6	-5.5	-6.2	-5.6	-4.8	-6.1	-4.0
Arm predicted mass (right)	6.3	32.2	64.4	-5.1	-6.8	-8.0	-5.2	-5.9	-5.3	-4.3	-5.8	-3.4
Basal metabolic rate	6.0	33.0	66.1	-5.0	-6.8	-8.1	-5.2	-5.8	-5.4	-4.6	-5.8	-3.8
Respiratory disease	5.6	12.5	19.0	3.9	3.4	2.9	3.7	3.9	2.8	3.8	2.6	4.4
Arm fat-free mass (left)	5.4	27.6	59.2	-4.6	-6.4	-7.7	-4.7	-5.4	-4.8	-4.0	-5.4	-3.0
Arm predicted mass (left)	5.4	27.4	56.6	-4.6	-6.3	-7.5	-4.8	-5.4	-4.9	-4.0	-5.3	-3.2
Medication: Bendroflumethiazide	4.9	7.5	10.0	3.1	2.5	1.5	3.2	3.2	2.6	2.8	2.9	2.5
Leg fat-free mass (left)	4.5	23.6	48.9	-4.1	-5.8	-7.0	-4.4	-4.8	-4.7	-3.9	-4.8	-3.1
Leg predicted mass (left)	4.4	23.2	47.9	-4.1	-5.7	-6.9	-4.4	-4.8	-4.6	-3.9	-4.8	-3.2
Heel T-Score	4.3	34.5	58.5	5.5	6.6	7.7	4.5	6.1	3.5	5.8	7.2	4.7
Worry too long after embarrassment	4.3	7.2	9.9	-2.7	-3.0	-2.8	-3.2	-3.0	-3.1	-1.5	-2.6	-1.8
Sensitivity / hurt feelings	4.2	7.2	11.6	-2.4	-3.1	-3.4	-2.8	-2.4	-3.3	-1.7	-2.4	-2.2
Leg fat-free mass (right)	4.0	21.5	45.6	-3.8	-5.6	-6.7	-4.3	-4.6	-4.6	-3.6	-4.5	-3.0
Leg predicted mass (right)	4.0	21.5	46.0	-3.8	-5.6	-6.8	-4.2	-4.6	-4.5	-3.6	-4.5	-3.0
Noisy workplace	3.6	4.4	6.3	2.3	2.2	2.3	2.0	2.3	1.8	1.9	2.5	1.6
Migraine (self-reported)	3.6	4.5	7.9	-2.0	-2.3	-1.7	-2.1	-2.4	-1.7	-2.1	-2.8	-1.7
Fluid intelligence score	3.4	7.0	8.2	-2.8	-2.5	-2.4	-2.9	-2.8	-2.5	-2.9	-2.2	-2.8
Weight	3.4	16.9	35.1	-3.5	-4.9	-5.9	-3.8	-4.0	-4.1	-3.2	-4.1	-2.5
Alzheimer’s Disease (in mother)	3.2	3.7	7.5	1.7	2.2	2.3	1.9	2.1	1.6	0.9	2.7	1.4
Verbal and Numeric Reasoning (VNR)	3.2	7.6	9.0	-2.8	-2.6	-2.8	-3.0	-3.0	-2.6	-2.9	-2.2	-2.9
Nervous feelings	3.1	5.7	7.7	-2.2	-2.8	-2.2	-2.5	-2.4	-2.6	-2.1	-2.5	-2.0
Asthma	2.8	5.5	8.9	2.7	2.0	1.2	2.6	2.5	2.0	3.0	1.4	2.9
Back pain experienced in last month	2.8	4.0	11.6	-0.9	-3.1	-3.4	-0.7	-1.7	-0.9	-0.5	-3.1	-0.0
Medication for hormone replacement therapy	2.7	3.0	4.8	2.1	1.7	0.8	1.7	2.0	1.2	1.4	2.2	2.0
Birth weight	2.7	6.0	7.8	-2.5	-2.7	-2.8	-2.6	-2.6	-2.5	-1.7	-2.7	-1.5
Medication for cholesterol	2.7	4.2	7.1	-2.7	-1.9	-0.1	-2.2	-2.4	-1.7	-1.8	-2.4	-2.1
Diastolic blood pressure, automated reading	2.7	8.5	9.9	2.8	3.0	2.7	3.1	3.1	2.7	2.7	3.1	2.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	2.5	3.0	5.1	1.6	1.7	2.3	1.6	1.9	1.2	1.6	2.1	1.3
Angina	2.4	3.2	6.8	2.1	1.6	1.1	1.7	2.2	1.1	1.9	2.6	0.9
Chronic bronchitis/emphysema (father)	2.4	2.9	3.8	1.7	1.7	1.4	1.9	1.8	1.8	1.3	1.9	1.6
Breast cancer (self-reported)	2.4	2.8	8.0	1.5	2.0	1.6	1.5	1.9	1.3	0.7	2.8	0.8
Diverticular disease/diverticulitis (self-reported)	2.3	2.7	4.5	1.9	1.6	1.7	1.5	1.9	0.8	1.6	2.1	1.2
Reason for reducing amount of alcohol drunk: Health precaution	2.3	2.7	5.4	1.5	1.6	1.1	2.1	1.7	2.3	1.0	1.6	1.2
Angina (self-reported)	2.3	3.1	6.6	2.0	1.7	1.2	1.7	2.1	1.1	1.9	2.6	0.8
Pain experienced in last month	2.3	3.8	6.7	1.1	2.6	2.5	1.9	2.2	2.0	1.2	2.2	1.1
Lung FVC	2.2	11.0	20.9	-3.3	-3.5	-3.5	-2.8	-3.7	-2.0	-2.7	-4.6	-3.0
Impedance of leg (right)	2.2	10.5	16.4	-4.0	-2.7	-1.4	-3.1	-3.5	-2.1	-3.6	-4.0	-3.6
Medication: Cholesterol lowering	2.2	3.4	8.7	2.0	1.8	1.5	1.6	2.1	0.9	1.5	2.9	1.5
Comparative body size at age 10	2.2	6.1	10.0	1.9	2.9	2.9	2.1	2.6	2.1	2.5	3.2	1.6
BMI	2.1	12.0	18.4	3.8	3.4	3.3	2.9	3.9	1.8	3.5	4.3	3.7
Ever unenthusiastic/disinterested for a whole week	2.1	2.5	4.3	-2.1	-1.2	-0.4	-1.7	-1.6	-1.4	-1.8	-1.3	-2.0
Impedance of arm (right)	2.1	9.6	15.6	-3.5	-2.5	-1.8	-2.9	-3.1	-2.2	-3.6	-3.6	-4.0
Wheeze or whistling in the chest in last year	2.1	3.7	6.2	2.0	1.6	1.6	2.0	2.0	1.5	2.5	1.5	2.3
Asthma (self-reported)	2.1	4.2	6.8	2.3	1.8	1.0	2.4	2.2	1.8	2.6	1.1	2.6
Financial situation satisfaction	2.1	2.6	5.2	-1.5	-1.4	-1.3	-2.2	-1.6	-2.3	-1.3	-1.4	-1.1
Medication: Blood pressure	2.1	4.0	7.8	2.7	1.5	-0.2	2.1	2.5	1.0	1.8	2.8	2.0
Happiness	2.0	2.4	3.5	-1.2	-1.6	-1.9	-1.8	-1.6	-1.7	-0.9	-1.5	-1.5
Crohns Disease (2017)	1.9	4.1	6.2	-1.8	-2.2	-2.5	-2.0	-2.1	-1.7	-1.7	-2.2	-1.9
Hypothyroidism (self reported)	1.9	4.3	7.2	-2.1	-2.7	-2.6	-1.8	-2.1	-1.9	-1.6	-2.4	-1.1
Hand grip strength (right)	1.9	5.1	7.0	-2.6	-2.1	-1.2	-2.3	-2.5	-1.7	-2.6	-2.3	-2.5
Impedance of arm (left)	1.9	9.0	13.1	-3.5	-2.4	-1.7	-2.9	-3.0	-2.1	-3.5	-3.6	-3.6
Leg pain on walking	1.9	2.4	3.9	-1.1	-1.8	-2.0	-1.4	-1.6	-1.4	-1.7	-1.3	-1.4
Ever had stillbirth, spontaneous miscarriage or termination	1.9	2.1	3.2	-1.8	-1.4	-1.8	-1.4	-1.4	-1.2	-1.3	-1.7	-0.5
Falls in the last year	1.8	2.4	5.4	-1.4	-1.6	-2.3	-1.0	-1.6	-0.6	-1.3	-2.0	-1.5
Impedance of whole body	1.8	9.4	14.9	-3.7	-2.4	-1.4	-2.9	-3.2	-2.1	-3.5	-3.9	-3.5
Intelligence (Savage-Jansen 2018)	1.7	5.1	7.8	-2.4	-1.9	-2.5	-2.3	-2.4	-1.9	-2.3	-1.7	-2.8
Crohns Disease (2012)	1.7	2.7	4.9	-1.6	-1.7	-2.2	-1.5	-1.8	-1.1	-1.4	-1.8	-1.4
Vitamin and mineral supplements	1.7	2.3	3.6	1.9	1.7	0.9	1.6	1.7	1.3	1.5	1.5	1.3
Body mass index (BMI)	1.7	7.2	10.8	3.2	2.5	2.0	2.4	3.0	1.4	2.9	3.3	2.9
Headache pain in last month	1.7	3.0	4.2	-1.4	-2.0	-2.0	-2.0	-1.7	-2.1	-1.0	-1.7	-1.3
Cholesterol lowering medication	1.7	2.5	4.3	2.1	1.6	1.0	1.8	1.7	1.7	1.4	1.6	0.9
Relative age voice broke	1.6	2.4	3.9	2.0	1.6	1.8	1.0	1.5	0.8	1.7	1.9	1.3
Impedance of leg (left)	1.6	7.8	12.0	-3.4	-2.1	-1.0	-2.7	-3.0	-1.8	-3.1	-3.5	-3.4
Tense / ‘highly strung’	1.6	2.6	3.5	-1.7	-1.6	-1.2	-1.8	-1.6	-1.5	-1.3	-1.9	-1.7
Alzheimer’s Disease (including proxy)	1.5	2.2	4.9	1.4	1.7	1.7	1.4	1.6	1.3	0.8	2.2	0.7
LDL Cholesterol	1.5	2.4	4.0	1.7	1.6	1.2	1.8	1.6	2.0	1.3	1.5	1.0
Rheumatoid Arthritis	1.5	2.1	4.0	-2.0	-1.3	-1.0	-1.5	-1.4	-1.4	-1.2	-1.4	-1.4
Hair/balding pattern: Pattern 2	1.5	2.0	3.3	-1.5	-1.4	-0.5	-1.6	-1.5	-1.5	-1.8	-0.9	-1.4
Qualifications: None of the above	1.5	3.3	4.4	2.1	1.4	1.9	2.0	1.9	1.8	1.8	1.1	2.1
Medication: Simvastatin	1.5	2.3	4.0	2.0	1.3	0.6	1.7	1.7	1.2	1.4	1.7	1.4
Trunk fat mass	1.4	6.2	12.0	-2.0	-2.8	-3.5	-2.5	-2.3	-2.8	-2.0	-2.3	-1.7
Had menopause	1.4	1.8	4.5	1.2	0.9	0.2	1.6	1.1	1.8	2.1	0.4	1.5
Hair/balding pattern: Pattern 4	1.4	3.4	4.9	1.8	2.2	0.9	2.0	2.1	1.9	2.2	1.9	1.2
Medication: Paracetamol	1.4	2.1	4.2	-0.5	-1.4	-1.4	-1.5	-1.3	-1.5	-1.6	-1.2	-2.0
Myopia	1.4	2.0	3.5	-1.6	-1.2	-1.8	-1.0	-1.7	-0.3	-1.6	-1.9	-1.1
Eye problems/disorders: Diabetes related eye disease	1.3	1.4	2.0	-1.1	-1.4	-1.4	-1.3	-1.2	-1.3	-1.2	-1.1	-0.7
Stomach or abdominal pain in last month	1.3	1.6	3.5	-1.0	-1.1	-0.3	-1.3	-1.5	-0.7	-1.4	-1.4	-1.9
Hearing difficulty/problems with background noise	1.3	2.1	4.2	-1.1	-1.6	-2.1	-1.6	-1.6	-1.5	0.0	-1.8	-0.8
Hip circumference	1.3	5.5	16.2	-1.5	-3.0	-4.0	-1.9	-2.1	-2.4	-1.6	-2.4	-0.4
Mouth/teeth dental problems: Bleeding gums	1.3	1.7	2.8	-0.7	-1.4	-0.8	-1.6	-1.5	-1.5	-1.1	-1.7	-1.1
Number of children fathered	1.3	1.5	3.6	1.2	1.3	-0.1	1.0	1.4	0.6	1.5	1.9	1.1
Qualifications: College or University degree	1.3	4.0	6.3	-1.6	-2.0	-2.5	-1.9	-2.0	-1.7	-1.6	-2.1	-2.4
Had major operations	1.3	1.5	2.7	-1.5	-1.1	-1.6	-0.9	-1.2	-0.6	-1.6	-0.7	-1.4
Supplements: Vitamin C	1.3	1.5	2.3	-1.5	-1.5	-0.6	-1.0	-1.4	-0.7	-1.5	-1.4	-1.1
Leg fat percentage (left)	1.3	4.5	5.9	2.4	2.3	2.1	1.9	2.4	1.3	2.2	2.4	1.9
Heel bone mineral density (BMD) T-score, automated (right)	1.2	2.8	6.6	1.5	1.9	2.4	0.7	1.6	0.5	1.5	2.6	0.9
Medication: Paracetamol	1.2	2.1	4.6	-0.7	-1.4	-1.3	-1.4	-1.2	-1.5	-1.6	-1.3	-2.1
Medication: Aspirin	1.2	1.5	4.2	1.7	1.2	-0.1	1.0	1.4	0.5	1.1	2.1	1.0
Illnesses of siblings: Diabetes	1.2	1.5	2.9	-1.0	-1.3	-0.7	-1.7	-1.5	-1.6	-1.1	-0.8	-0.5
Friendships satisfaction	1.2	1.5	2.9	-1.4	-1.0	-0.6	-1.7	-1.4	-1.4	-0.8	-1.1	-1.2
Pulse wave reflection index	1.1	1.4	3.2	0.4	1.4	1.8	0.9	0.9	1.2	1.0	1.2	1.2
Hypothyroidism/myxoedema (self-reported)	1.1	2.2	4.8	-1.4	-2.2	-2.0	-1.0	-1.3	-1.3	-1.1	-1.6	-0.6
Medication: Seretide 50 evohaler	1.1	1.2	2.8	1.3	0.7	0.1	1.4	1.0	1.5	1.1	-0.1	1.7
Medication: Aspirin	1.1	1.4	3.4	1.6	1.2	-0.1	1.0	1.3	0.7	1.1	1.8	0.8
High cholesterol (Self-reported)	1.1	2.0	3.6	1.9	1.3	0.8	1.6	1.6	1.4	1.2	1.7	1.0
Ovarian Cancer	1.0	1.3	4.5	-0.5	-1.5	-2.1	-0.7	-1.2	-0.6	-0.0	-1.5	-0.2
Heel bone mineral density (BMD) T-score, automated (left)	1.0	2.2	5.5	1.2	1.8	2.3	0.7	1.4	0.6	1.3	2.1	0.8
Medication: Atenolol	1.0	1.3	2.2	1.1	1.0	1.1	1.5	1.2	1.5	0.8	1.2	0.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.0	1.2	1.9	1.0	1.2	1.4	1.0	1.1	0.8	1.1	1.4	0.8
Tinnitus: Yes, now most or all of the time	1.0	1.2	3.1	1.2	1.0	1.1	0.8	0.9	0.8	1.0	1.8	1.0
Medication: Lisinopril	1.0	1.2	3.2	1.1	1.1	0.4	0.9	1.5	0.1	0.5	1.8	1.5
Heart disease (siblings)	1.0	1.2	1.8	-1.1	-0.9	-0.9	-1.3	-1.0	-1.3	-1.0	-0.9	-1.2
Worry (Nagel 2018)	0.9	1.9	2.8	-1.4	-1.3	-0.6	-1.6	-1.3	-1.6	-1.7	-1.1	-1.6
Medication: Levothyroxine sodium	0.9	1.5	3.9	-0.9	-1.8	-2.0	-0.8	-0.8	-1.4	-1.1	-0.9	-0.4
Had other major operations	0.9	1.1	2.0	1.2	0.6	-0.6	1.2	0.9	1.1	1.0	1.1	1.4
Medication: Lansoprazole	0.9	1.0	3.7	0.4	0.6	0.2	1.1	0.7	1.2	1.3	0.6	1.9
Prospective memory result	0.9	1.2	2.0	-1.2	-1.1	-1.2	-0.9	-1.2	-0.5	-1.0	-1.4	-0.9
Glaucoma (self-reported)	0.9	1.1	2.8	0.9	0.8	0.2	1.3	0.8	1.7	1.4	0.6	0.9
High blood pressure (siblings)	0.9	1.3	2.6	1.6	0.6	0.4	1.0	1.4	0.2	1.3	1.3	1.5
Ever had bowel cancer screening	0.9	1.1	2.2	1.5	0.5	0.0	1.0	1.1	0.5	1.1	1.4	1.4
Supplements: Zinc	0.8	0.9	1.8	-0.5	-1.1	-1.3	-0.9	-0.9	-0.9	-1.1	-0.6	-0.9
Mouth/teeth dental problems: Dentures	0.8	1.3	2.9	0.8	1.1	1.1	1.0	1.1	0.7	0.6	1.7	1.5
Ever highly irritable/argumentative for 2 days	0.8	1.0	2.1	-1.1	-1.0	-0.4	-1.3	-1.0	-1.4	-0.9	-0.6	-0.8
Shortness of breath walking on level ground	0.8	0.9	3.2	0.8	0.9	0.0	0.9	1.1	0.5	0.6	1.8	1.0
Medication: Ibuprofen	0.8	1.0	2.9	-0.5	-1.2	-0.9	-0.6	-1.2	-0.2	-0.9	-1.7	-1.0
Suffer from ‘nerves’	0.8	1.3	2.8	-1.2	-0.9	-0.5	-1.1	-1.0	-0.9	-1.6	-1.0	-1.7
Chest pain or discomfort	0.8	1.1	3.4	-0.9	-1.1	-0.5	-1.6	-1.1	-1.8	-0.0	-0.8	-0.2
Mood swings	0.8	1.4	3.4	1.1	1.4	1.8	1.0	1.3	0.9	0.8	1.2	0.7
Risk taking	0.8	1.2	2.2	-1.1	-1.1	-1.2	-0.9	-1.3	-0.5	-0.6	-1.5	-1.4
Bipolar Disorder or Schizophrenia	0.7	1.6	2.6	1.3	1.4	1.3	1.6	1.5	1.4	0.9	1.0	0.8
Hand grip strength (left)	0.7	2.0	2.8	-1.6	-1.5	-0.9	-1.7	-1.7	-1.5	-1.3	-1.4	-0.8
Diabetes (father)	0.7	0.9	2.9	-1.7	-0.6	-0.6	-1.0	-1.0	-0.8	-0.9	-0.6	-0.9
Bilateral oophorectomy (both ovaries removed)	0.7	0.8	1.7	0.6	1.0	0.1	1.1	0.9	1.3	0.2	1.2	-0.5
Multivitamins +/- minerals	0.7	0.8	1.5	-1.2	-0.8	-0.4	-1.0	-0.9	-0.8	-0.9	-0.6	-1.2
Arm fat percentage (right)	0.7	2.6	4.2	2.0	1.7	1.3	1.4	2.0	0.7	1.5	2.0	1.2
Loud music exposure frequency	0.7	0.7	1.4	-0.4	-1.2	-1.1	-0.8	-0.8	-0.9	-0.7	-0.4	-0.8
Leg fat percentage (right)	0.7	2.7	3.5	1.9	1.8	1.6	1.4	1.9	0.9	1.6	1.8	1.6
Whole body fat mass	0.7	2.8	7.0	-1.1	-1.9	-2.6	-1.6	-1.4	-2.1	-1.1	-1.4	-1.0
Hypertension (Self-reported)	0.7	2.0	4.8	1.7	1.0	0.1	1.1	1.8	-0.0	1.3	2.2	1.7
Arm fat percentage (left)	0.7	2.8	4.4	2.0	1.8	1.3	1.5	2.1	0.7	1.6	2.1	1.4
Commuting to job workplace: Walk	0.7	0.7	2.1	0.6	0.5	0.0	1.2	0.6	1.4	1.0	0.0	0.9
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.7	1.5	2.4	-0.8	-1.4	-1.2	-1.1	-1.2	-1.1	-1.5	-1.5	-1.0
Commuting to job workplace: Public transport	0.7	0.8	2.0	-1.4	-0.6	-0.5	-0.8	-0.9	-0.5	-1.1	-1.0	-0.7
Supplements: Fish oil (including cod liver oil)	0.7	1.0	1.2	-1.0	-1.0	-1.1	-1.0	-1.1	-0.7	-1.1	-0.6	-1.1
Irritability	0.7	1.2	3.8	0.9	1.0	2.0	0.9	1.1	0.7	1.2	1.0	0.6
Ever depressed for a whole week	0.7	0.9	2.0	-1.0	-0.8	-0.5	-1.1	-0.7	-1.4	-0.8	-0.8	-0.9
Commuting to job workplace: Cycle	0.7	0.8	1.9	0.2	-0.9	-1.0	-1.1	-0.7	-1.4	-0.0	-1.2	-0.7
Schizophrenia (2018)	0.6	1.3	1.7	1.2	1.1	1.3	1.3	1.3	1.0	0.9	0.7	1.1
Major Depression (MDD)	0.6	0.8	2.0	-1.1	-0.8	-0.5	-1.1	-0.8	-1.4	-0.5	-0.7	-0.2
Body Mass Index (BMI) (2010)	0.6	0.8	1.3	1.2	1.0	1.1	0.6	0.9	0.3	0.9	1.2	0.8
Waist Hip Ratio (WHR)	0.6	2.9	9.6	-1.6	-0.9	-1.0	-1.8	-1.7	-1.0	-1.2	-1.9	-3.1
Ever used hormone-replacement therapy (HRT)	0.6	0.7	2.5	0.7	1.0	0.3	1.2	0.7	1.6	0.6	0.5	0.3
Allergy	0.6	1.4	2.9	-1.4	-0.7	-0.3	-1.3	-1.5	-0.6	-1.4	-0.8	-1.7
Emphysema/chronic bronchitis	0.6	0.7	3.6	0.5	-0.0	-0.7	0.5	0.7	-0.1	0.9	0.4	1.9
Commuting to job workplace: Car/motor vehicle	0.6	0.7	1.2	0.4	1.0	1.1	0.7	0.7	0.9	1.0	0.6	0.7
Illnesses of father: Heart disease	0.6	0.9	2.8	-1.7	-0.4	0.4	-0.7	-0.9	-0.3	-0.7	-0.3	-1.6
Handedness (chirality/laterality): Left-handed	0.6	0.8	2.0	1.4	0.8	0.3	0.7	1.0	0.1	0.8	1.0	1.0
Qualifications: nursing, teaching	0.6	0.9	2.7	-0.5	-0.6	-1.2	-1.0	-0.7	-1.0	-0.6	-0.7	-1.6
Mineral and other dietary supplements	0.6	0.8	1.6	0.9	0.9	0.9	0.8	1.0	0.4	1.2	0.6	1.3
Illnesses of father: High blood pressure	0.6	0.8	2.3	-1.3	-1.0	-1.5	-0.7	-0.8	-0.6	-0.2	-0.6	-0.4
Number of operations (self-reported)	0.6	0.9	4.3	-0.7	-1.0	-2.1	-0.1	-0.7	0.2	-0.8	-0.6	-0.8
Vascular/heart problems diagnosed by doctor	0.6	1.6	6.0	-1.4	-1.1	-0.2	-0.9	-1.6	-0.0	-1.0	-2.4	-0.9
Alcohol drinker status: Previous	0.6	0.6	1.4	0.8	0.3	0.6	0.6	0.9	0.1	1.0	1.2	1.1
Depressed Affect (Nagel 2018)	0.5	1.1	1.8	0.9	1.4	1.3	1.0	1.2	1.0	0.7	1.4	0.6
Age at First Birth	0.5	0.7	2.3	-0.0	0.8	1.4	0.8	0.3	1.5	0.6	0.3	0.4
Lung FEV1/FVC ratio	0.5	2.5	6.7	-0.8	-1.1	0.2	-2.1	-1.1	-2.5	-1.4	-0.3	-2.6
Hearing difficulty/problems: Yes	0.5	0.7	2.8	0.7	0.3	-0.0	0.3	0.6	0.1	1.7	0.8	1.4
Systolic blood pressure, automated reading	0.5	1.5	2.8	1.3	0.8	0.3	1.4	1.4	0.9	1.5	1.4	1.7
High blood pressure	0.5	1.5	4.4	1.5	0.9	0.1	0.9	1.6	-0.1	1.1	2.1	1.3
Supplements: Glucosamine	0.5	0.7	2.6	-0.1	-0.6	-0.9	-0.3	-0.7	0.2	-1.1	-0.9	-1.6
Financial difficulties in last 2 years	0.5	0.7	1.8	-0.7	-0.8	-0.3	-1.1	-0.7	-1.3	-0.7	-0.8	-0.4
Heart attack	0.5	0.7	1.7	-0.6	-0.5	-0.2	-0.9	-0.4	-1.3	-1.2	0.6	-0.8
Medication: Ramipril	0.5	0.6	1.6	0.9	0.6	0.6	0.5	1.0	0.0	0.8	1.3	0.9
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.8	1.2	-1.0	-1.0	-0.7	-1.0	-0.9	-0.9	-1.1	-0.7	-0.6
Pulse rate	0.5	0.8	1.7	1.3	0.9	0.7	1.0	1.0	1.0	0.5	0.9	0.2
Pulse wave peak to peak time	0.5	0.6	0.9	-0.4	-0.7	-0.8	-0.8	-0.7	-1.0	-0.7	-0.8	-0.8
Age at last live birth	0.5	0.7	1.4	-0.8	-1.2	-1.1	-0.8	-1.0	-0.7	-0.8	-0.6	-0.6
Number of self-reported non-cancer illnesses	0.5	0.9	2.1	1.2	-0.6	-1.5	0.7	0.6	-0.1	1.2	-0.3	1.3
Average weekly champagne plus white wine intake	0.5	0.7	1.6	-0.3	-1.0	-0.8	-0.9	-0.6	-1.3	-0.8	-0.8	-0.7
Miserableness	0.5	0.9	2.9	0.7	1.4	0.9	0.3	1.0	0.2	0.9	1.7	0.3
Heart attack/myocardial infarction (self-reported)	0.5	0.6	1.6	-0.5	-0.5	-0.1	-0.8	-0.3	-1.3	-1.2	0.7	-0.7
Schizophrenia vs Biploar Disorder	0.4	0.5	1.6	-0.5	0.1	0.8	-0.2	-0.3	0.2	-1.3	0.2	-1.2
Bipolar Disorder (2011)	0.4	0.4	1.4	-0.2	0.6	0.8	0.4	0.2	0.8	-0.3	0.1	-1.2
Chronotype (morning person)	0.4	0.9	1.5	0.9	1.1	1.2	0.9	0.9	1.0	0.7	0.8	0.8
Number of treatments/medications taken	0.4	0.7	1.3	1.0	0.6	-0.2	1.1	0.9	1.0	0.8	1.1	0.4
Other serious medical condition/disability diagnosed by doctor	0.4	0.5	1.5	-0.3	-1.2	-1.1	-0.2	-0.6	-0.2	0.2	-1.2	0.3
Tinnitus: Yes, but not now, but have in the past	0.4	0.4	1.4	-0.0	-0.7	-0.5	-0.8	-0.6	-0.9	0.1	-1.2	0.3
Serious illness, injury or assault to yourself	0.4	0.4	2.0	-0.1	-0.7	-1.4	-0.5	-0.6	-0.4	0.3	-0.5	0.6
Waist circumference	0.4	1.4	5.6	-0.4	-1.4	-2.4	-1.0	-0.9	-1.4	-0.4	-1.0	-0.5
Alcohol usually taken with meals	0.4	0.6	1.7	-0.4	-0.5	-0.3	-1.0	-0.5	-1.3	-0.9	-0.3	-1.1
Pain all over the body in last month	0.4	0.4	2.0	0.8	-0.2	0.0	-0.0	0.2	-0.5	0.4	0.7	1.4
Illnesses of siblings	0.4	0.5	2.0	0.1	0.8	0.8	0.9	0.3	1.4	0.4	-0.1	0.5
Neuroticism score	0.4	0.8	2.0	-1.0	-0.8	-0.4	-1.4	-0.9	-1.4	-0.6	-0.3	-0.8
Father’s age at death	0.4	0.6	1.1	0.8	0.8	0.7	0.5	0.8	0.5	1.0	0.6	1.0
Depression (self-reported)	0.4	0.5	1.7	-0.3	-0.8	-0.8	-0.3	-0.5	-0.4	-0.7	-1.3	-0.5
Breastfed as a baby	0.4	0.5	2.1	0.4	0.4	-0.2	0.1	0.5	-0.3	-0.3	1.5	-1.2
Medication for cholesterol, blood pressure or diabetes	0.4	0.7	3.8	-1.1	-0.5	-0.1	-0.4	-1.0	0.3	-0.4	-1.9	-0.2
Medication: Ventolin 100micrograms inhaler	0.4	0.5	2.1	0.4	0.4	0.5	0.3	0.2	0.3	1.2	0.3	1.4
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.5	2.4	0.4	0.3	0.4	0.8	0.7	0.4	0.6	0.1	1.6
Number of full sisters	0.4	0.5	1.2	-0.7	-0.7	0.2	-1.0	-0.6	-1.1	-0.5	-0.5	-0.4
Guilty feelings	0.4	0.6	1.5	-0.7	-0.8	-0.6	-1.2	-1.0	-1.1	-0.5	-0.2	-0.2
Hearing aid user	0.4	0.5	2.5	0.4	0.2	0.0	-0.0	0.5	-0.5	0.2	1.6	1.0
Alcohol drinker status: Never	0.4	0.4	2.6	-0.4	-0.8	-1.6	-0.2	-0.5	-0.1	0.1	-0.4	0.0
Fractured/broken bones in last 5 years	0.4	0.5	0.9	0.9	0.5	0.6	0.9	0.7	0.8	0.4	0.9	0.7
Pack years of smoking	0.4	0.6	3.0	0.8	0.3	-0.1	0.6	0.5	0.5	0.9	0.3	1.7
Bipolar Disorder (2018)	0.3	0.5	0.9	0.5	0.8	0.5	1.0	0.8	1.0	0.4	0.8	-0.0
Neuroticism (Nagel 2018)	0.3	0.6	1.1	-0.7	-0.9	-0.3	-1.0	-0.7	-1.1	-0.7	-0.6	-0.8
Irritable Bowel Disease (IBD)	0.3	0.6	1.0	-0.7	-0.9	-0.7	-0.8	-0.7	-0.9	-1.0	-0.6	-0.7
Fasting Glucose	0.3	0.3	0.7	-0.4	0.8	0.8	0.4	0.4	0.8	0.5	0.1	-0.4
HDL Cholesterol	0.3	0.4	1.3	0.1	-0.4	-0.7	-0.3	-0.3	-0.6	-0.7	-0.9	-1.1
Cardiovascular Disease	0.3	0.9	2.1	1.4	0.8	0.3	0.6	1.2	-0.2	0.9	1.3	1.0
Ever had hysterectomy (womb removed)	0.3	0.3	1.8	-0.2	0.4	0.1	0.9	0.2	1.3	-0.0	-0.4	-0.3
Medication: Co-codamol	0.3	0.4	1.1	-0.4	-1.1	-0.6	-0.5	-0.6	-0.8	-0.4	-0.3	0.3
Pack years adult smoking proportion	0.3	0.5	2.8	0.6	0.2	0.0	0.6	0.4	0.5	0.8	0.1	1.7
Fed-up feelings	0.3	0.5	1.1	1.0	0.7	0.6	0.7	0.8	0.5	0.5	0.5	1.0
Taking other prescription medications	0.3	0.5	2.6	0.4	-0.6	-1.6	0.5	0.4	-0.1	0.8	0.0	0.7
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.5	0.9	-0.9	-0.5	-0.8	-0.9	-0.6	-0.8	-0.7	-0.6	-0.5
Diabetes (self-reported)	0.3	0.5	1.7	0.8	0.7	0.7	0.5	0.6	0.4	0.1	1.3	0.4
Hayfever/allergic rhinitis (self-reported)	0.3	0.5	0.8	-0.7	-0.8	-0.5	-0.8	-0.7	-0.9	-0.6	-0.6	-0.3
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.4	1.7	0.1	-0.9	-0.4	-0.0	-0.6	0.2	-0.7	-1.3	-0.5
Illnesses of mother	0.3	0.3	1.2	-0.7	0.1	-0.1	-0.2	-0.5	0.2	-0.4	-1.1	-0.8
Length of working week for main job	0.3	0.3	1.0	-0.3	-0.3	-1.0	-0.8	-0.5	-0.9	-0.5	-0.0	-0.2
Medication: Amlodipine	0.3	0.4	1.4	0.1	-0.1	-0.1	-0.6	0.1	-1.2	-0.9	0.8	-0.7
Number of full brothers	0.3	0.4	1.0	0.7	0.2	0.1	0.7	0.7	0.3	1.0	0.3	0.8
Neck or shoulder pain in last month	0.3	0.5	1.4	-0.4	-0.6	-0.2	-0.8	-0.7	-0.7	-0.3	-0.9	-1.2
Mean time to correctly identify matches	0.3	0.6	1.5	0.6	0.5	0.6	0.9	1.0	0.6	1.2	0.6	0.0
Osteoporosis (self-reported)	0.3	0.4	1.2	0.5	0.5	-0.1	0.8	0.4	1.1	0.5	0.1	0.9
Wears glasses or contact lenses	0.3	0.4	0.7	0.8	0.6	0.4	0.5	0.8	0.2	0.3	0.8	0.8
Ever had prostate specific antigen (PSA) test	0.3	0.3	0.8	0.1	-0.9	-0.9	0.1	-0.2	-0.2	-0.2	-0.7	0.7
Unable to work because of sickness or disability	0.3	0.4	0.8	0.4	0.3	0.2	0.9	0.5	0.8	0.8	0.4	0.8
Basal cell carcinoma (self-reported)	0.3	0.4	1.2	0.1	-0.7	-0.4	-0.9	-0.6	-1.1	0.2	-0.5	0.4
Alzheimer’s Disease (in father)	0.2	0.2	1.1	0.3	0.6	0.3	0.0	0.3	0.1	0.1	1.1	-0.5
Ulcerative Colitis (UC)	0.2	0.4	0.9	0.6	0.7	1.0	0.7	0.9	0.4	0.2	0.8	0.2
Reaction Time	0.2	0.4	1.2	0.5	0.4	0.7	0.5	0.8	0.1	1.1	0.4	-0.3
Lupus	0.2	0.2	0.7	0.6	0.1	0.6	-0.1	0.2	-0.3	-0.6	0.8	-0.5
Triglycerides	0.2	0.3	0.9	0.2	0.5	0.9	0.5	0.3	0.6	0.3	0.9	0.4
Ulcerative Colitis	0.2	0.2	0.7	0.6	0.1	0.1	0.8	0.8	0.1	0.1	0.6	0.4
Smoking Status	0.2	0.4	0.8	-0.5	-0.3	-0.0	-0.5	-0.6	-0.4	-0.8	-0.9	-0.7
Hair Pigment	0.2	4.7	6.6	2.5	2.1	2.6	2.2	2.2	1.9	2.1	1.8	2.1
Medication: Metformin	0.2	0.2	1.0	0.6	0.5	0.3	0.0	0.4	-0.1	0.3	1.0	0.5
Diabetes (mother)	0.2	0.2	0.6	-0.4	-0.6	-0.1	-0.3	-0.7	-0.1	0.4	-0.8	0.4
Severe depression (siblings)	0.2	0.3	0.9	-0.5	-0.3	0.4	-0.7	-0.2	-1.0	-0.2	0.0	-0.6
Trunk fat percentage	0.2	0.9	2.1	-0.6	-0.9	-1.2	-1.0	-0.6	-1.5	-0.7	-0.7	-0.7
Average weekly fortified wine intake	0.2	0.2	0.6	-0.5	-0.3	-0.7	0.4	-0.2	0.6	0.2	-0.6	0.6
Maternal smoking around birth	0.2	0.3	0.7	0.5	0.4	0.9	0.0	0.4	-0.2	0.3	0.8	0.7
High blood pressure (mother)	0.2	0.3	1.1	-0.1	-0.5	-0.4	-0.7	-0.3	-1.1	-0.5	0.6	-0.3
Number of incorrect matches in round	0.2	0.4	0.6	0.8	0.5	-0.1	0.8	0.7	0.7	0.7	0.6	0.4
Alcohol intake versus 10 years previously	0.2	0.3	0.8	-0.9	-0.6	0.1	-0.7	-0.5	-0.9	-0.1	-0.2	0.2
Hair/balding pattern: Pattern 3	0.2	0.3	1.1	0.2	-0.4	-0.7	0.3	-0.1	0.4	0.7	-1.0	0.7
Qualifications: A levels/AS levels or equivalent	0.2	0.4	0.9	0.7	0.8	1.0	0.3	0.6	0.2	0.4	0.7	0.1
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.3	0.6	-0.6	-0.1	0.5	-0.4	-0.5	-0.0	-0.7	-0.6	-0.8
Exposure to tobacco smoke at home	0.2	0.2	0.6	0.5	0.3	-0.0	0.5	0.5	0.2	0.7	0.8	0.3
Birth weight of first child	0.2	0.4	2.5	-0.4	-0.4	-1.6	-0.4	-0.4	-0.4	-0.3	-0.1	-0.6
Gout (self-reported)	0.2	0.3	1.2	0.1	-0.5	-0.4	-0.5	-0.4	-0.6	-0.2	-0.6	-1.1
Chronic bronchitis/emphysema (mother)	0.2	0.3	0.8	0.5	0.1	0.3	0.8	0.5	0.5	0.0	0.3	0.9
Exposure to tobacco smoke outside home	0.2	0.3	1.1	-0.1	-0.7	-0.5	-0.5	-0.4	-0.6	0.1	-1.1	-0.5
Age at first live birth	0.2	0.4	1.9	-0.4	-0.3	-0.8	-0.3	-0.5	0.0	-0.6	-0.2	-1.4
Mouth/teeth dental problems: Loose teeth	0.2	0.2	1.0	0.1	0.2	-0.2	-0.0	-0.2	0.4	0.4	-0.6	1.0
Medication: Blood pressure	0.2	0.4	2.1	0.8	0.3	0.0	0.2	0.8	-0.4	-0.1	1.5	-0.2
Overall health rating	0.2	0.4	1.3	0.9	-0.2	-0.7	0.3	0.2	0.1	0.7	0.1	1.1
Family relationship satisfaction	0.2	0.2	0.7	-0.3	-0.4	-0.0	-0.6	-0.3	-0.8	0.0	-0.4	-0.4
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.3	0.8	-0.1	0.4	0.9	0.5	0.2	0.8	-0.1	0.4	-0.5
Illness, injury, bereavement, stress in last 2 years	0.2	0.3	1.4	-0.2	0.1	-0.4	0.1	-0.3	0.6	-0.7	-0.2	-1.2
Smoking status: Previous	0.2	0.2	0.7	0.1	-0.2	-0.9	-0.2	-0.0	-0.4	-0.3	-0.5	-0.9
Loneliness, isolation	0.2	0.3	1.3	-0.5	-0.1	-0.2	-0.5	-0.4	-0.4	-0.8	-0.1	-1.2
Long-standing illness, disability or infirmity	0.2	0.3	1.3	0.5	-0.6	-1.2	0.2	0.2	-0.2	0.5	-0.7	-0.1
Illnesses of father: None of the above (group 1)	0.2	0.2	0.5	0.7	0.1	-0.1	0.7	0.4	0.5	0.1	-0.5	0.6
Mother’s age at death	0.2	0.3	1.4	0.1	-0.5	-1.2	-0.2	-0.2	-0.4	-0.4	-0.1	-0.6
Pain type(s) experienced in last month: Hip pain	0.2	0.2	0.9	0.3	-0.6	-0.9	-0.3	-0.4	-0.4	-0.1	0.1	-0.4
Age started oral contraceptive pill	0.2	0.2	1.2	-0.3	-0.6	-1.1	-0.2	-0.3	-0.1	-0.1	-0.2	-0.6
Medication: Omeprazole (e.g. Zanprol)	0.2	0.3	0.5	0.7	0.2	-0.2	0.4	0.7	-0.3	0.4	0.7	0.6
Depression (Nagel 2018)	0.1	0.2	0.5	-0.1	0.6	-0.0	0.3	0.3	0.7	-0.4	0.4	-0.3
Prostate Cancer	0.1	0.1	0.7	-0.0	-0.0	0.1	-0.4	-0.0	-0.6	-0.0	0.1	-0.8
Coronary Artery Disease (CAD)	0.1	0.2	0.9	0.1	0.5	0.0	0.5	0.2	0.9	0.3	0.0	0.2
Mean Putamen Volume	0.1	0.1	0.8	-0.2	0.1	0.6	-0.3	-0.2	-0.2	-0.9	0.2	0.1
HbA1C	0.1	0.2	0.5	-0.5	0.6	0.7	-0.4	-0.2	-0.2	0.0	-0.1	-0.2
Neuroticism (2016)	0.1	0.2	0.8	0.3	0.4	0.9	0.1	0.4	0.0	-0.1	0.5	-0.2
Primary Biliary Cirrhosis	0.1	0.2	0.5	0.0	-0.4	-0.5	0.5	0.0	0.5	0.3	-0.2	0.7
Type 2 Diabetes (T2D) (2012)	0.1	0.1	0.4	0.5	-0.1	-0.1	0.5	0.2	0.4	0.4	0.1	0.6
Blood Eosinophil Count	0.1	0.7	1.8	-1.3	-0.5	-0.1	-0.3	-1.0	0.3	-0.7	-0.9	-1.1
Blood Platelet Count	0.1	0.8	2.5	-0.8	-0.7	-1.6	-0.9	-1.1	-0.2	-0.2	-0.9	-0.6
Blood Red Count	0.1	0.5	1.7	-0.5	-0.3	-0.4	-1.2	-0.6	-1.3	0.3	0.1	-0.6
Type 2 Diabetes (T2D) (2018)	0.1	0.2	0.7	0.1	0.4	0.2	0.1	0.4	-0.1	-0.1	0.8	0.6
Neuroticism	0.1	0.2	0.4	-0.4	0.0	0.3	-0.7	-0.2	-0.7	-0.4	0.3	-0.5
Tanning	0.1	0.9	1.5	0.8	1.1	0.7	1.1	0.9	1.2	0.7	0.6	1.1
Average weekly spirits intake	0.1	0.2	0.8	0.0	0.1	-0.3	0.8	0.3	0.9	0.0	0.0	-0.1
Frequency of depressed mood in last 2 weeks	0.1	0.2	0.5	0.1	0.7	0.6	0.3	0.5	0.4	-0.0	0.3	0.5
Relative age of first facial hair	0.1	0.1	0.5	0.4	-0.3	-0.2	-0.1	-0.1	-0.4	0.3	0.1	0.7
Current tobacco smoking	0.1	0.2	0.8	-0.7	0.3	0.9	-0.1	-0.4	0.4	-0.5	-0.1	-0.2
Age when periods started (menarche)	0.1	0.2	1.3	0.1	0.5	1.1	0.2	0.2	0.2	0.3	0.3	0.5
Qualifications: CSEs or equivalent	0.1	0.2	0.5	-0.3	-0.0	0.6	-0.0	0.1	-0.1	0.5	0.5	0.7
Mouth/teeth dental problems	0.1	0.2	0.4	0.3	0.4	0.2	0.5	0.6	0.2	0.4	0.6	0.0
Time employed in main current job	0.1	0.2	0.7	-0.8	-0.2	-0.2	-0.3	-0.5	-0.0	-0.5	-0.0	-0.2
Number of live births	0.1	0.1	0.3	-0.3	0.0	0.4	-0.2	-0.0	-0.4	-0.2	0.6	0.4
Lung cancer (father)	0.1	0.2	0.7	0.1	0.2	-0.1	-0.1	0.1	0.1	-0.8	0.3	-0.8
Pulse wave Arterial Stiffness index	0.1	0.2	0.5	-0.7	-0.5	-0.4	-0.2	-0.5	0.1	-0.3	-0.5	-0.2
Arm fat mass (right)	0.1	0.5	2.5	0.1	-0.8	-1.6	-0.5	-0.3	-1.1	-0.2	-0.2	-0.1
Qualifications: O levels/GCSEs or equivalent	0.1	0.1	0.9	-0.4	0.0	-0.1	-0.2	0.0	-0.4	-0.0	0.2	1.0
Blood clot in the leg (DVT)	0.1	0.1	0.3	-0.2	-0.4	-0.6	0.0	-0.0	-0.2	-0.2	-0.2	0.0
Health satisfaction	0.1	0.2	0.7	0.3	-0.3	-0.8	-0.3	-0.2	-0.5	-0.0	-0.0	0.4
Eye problems/disorders: None of the above	0.1	0.1	0.3	0.0	-0.2	0.0	-0.2	-0.3	-0.1	0.1	-0.4	0.6
Medication for pain relief, constipation, heartburn	0.1	0.2	0.6	-0.8	0.3	0.8	0.1	-0.2	0.5	0.2	-0.3	0.3
Medication: Allopurinol	0.1	0.1	0.3	0.4	-0.4	-0.4	-0.2	-0.1	-0.5	-0.2	-0.2	-0.5
Medication: Omeprazole	0.1	0.1	0.3	0.4	0.2	-0.3	0.2	0.5	-0.4	-0.1	0.3	-0.1
Leg fat mass (right)	0.1	0.3	1.4	0.1	-0.6	-1.2	-0.5	-0.2	-1.0	-0.1	-0.1	0.0
Alcohol intake frequency.	0.1	0.3	0.7	-0.7	-0.7	-0.3	-0.5	-0.5	-0.5	0.2	0.2	0.9
Knee pain experienced in last month	0.1	0.1	0.3	-0.1	-0.1	-0.3	-0.3	-0.4	-0.3	-0.5	-0.2	-0.4
Average weekly red wine intake	0.1	0.2	1.3	0.1	-0.3	-1.1	0.0	-0.2	0.1	0.2	-0.5	0.0
Diabetes diagnosed by doctor	0.1	0.2	0.9	0.6	0.4	0.1	0.2	0.4	0.0	-0.1	1.0	0.6
Eye problems/disorders: Cataract	0.1	0.1	0.3	-0.5	-0.2	0.3	-0.2	-0.2	-0.1	-0.3	-0.0	-0.0
Mouth/teeth dental problems: Mouth ulcers	0.1	0.1	0.5	-0.0	-0.1	-0.3	0.0	0.0	0.0	0.7	-0.2	0.2
Osteoarthritis (self-reported)	0.1	0.2	0.9	0.4	0.4	0.2	0.6	0.2	0.9	-0.2	-0.2	0.1
Smoking status: Current	0.1	0.2	0.7	-0.7	0.2	0.8	-0.3	-0.5	0.1	-0.6	-0.1	-0.3
Arm fat mass (left)	0.1	0.4	2.3	0.0	-0.7	-1.5	-0.4	-0.2	-1.0	-0.1	-0.0	0.1
Ever taken oral contraceptive pill	0.1	0.2	0.5	0.4	0.2	0.3	0.5	0.2	0.7	0.1	-0.5	-0.1
Eye problems/disorders: Glaucoma	0.1	0.1	0.4	-0.5	0.2	-0.2	0.0	-0.3	0.6	0.3	-0.1	-0.2
Medication: Atorvastatin	0.1	0.1	0.3	0.0	-0.2	0.1	-0.2	-0.2	-0.2	-0.5	0.4	-0.1
Average weekly beer plus cider intake	0.1	0.2	0.8	-0.1	-0.0	0.9	0.2	0.3	-0.2	-0.0	-0.2	0.8
Supplements: Calcium	0.1	0.1	0.5	-0.4	-0.4	-0.3	0.5	-0.1	0.7	0.1	-0.3	-0.0
Leg fat mass (left)	0.1	0.2	1.0	0.3	-0.4	-1.0	-0.3	0.0	-0.8	0.1	0.1	0.1
Breast Cancer	0.0	0.1	0.3	-0.1	-0.3	-0.4	0.3	0.1	0.3	0.0	-0.3	0.5
Schizophrenia (2014)	0.0	0.1	0.3	-0.0	0.1	0.6	0.3	0.3	0.1	-0.3	-0.2	-0.2
Blood White Count	0.0	0.3	1.4	-0.2	0.1	-0.1	0.1	-0.2	0.1	-1.2	0.9	-0.0
Systolic Blood Pressure	0.0	0.2	0.7	0.0	-0.4	-0.6	0.5	0.2	0.3	0.5	-0.0	0.8
Allergy or Eczema	0.0	0.0	0.1	-0.1	-0.0	-0.1	0.0	0.2	-0.2	-0.2	0.2	-0.3
Townsend deprivation index at recruitment	0.0	0.1	0.4	0.1	-0.3	-0.0	0.1	-0.0	0.0	0.1	-0.6	-0.0
Frequency of unenthusiasm / disinterest in last 2 weeks	0.0	0.1	0.2	-0.1	0.0	-0.3	0.2	0.2	0.0	-0.1	0.2	0.5
Hayfever, allergic rhinitis or eczema	0.0	0.0	0.1	-0.1	-0.2	-0.4	0.0	0.2	-0.2	0.1	0.0	0.2
Past tobacco smoking	0.0	0.1	0.2	-0.4	-0.3	0.2	0.0	-0.2	0.2	0.1	0.1	0.2
Worrier / anxious feelings	0.0	0.1	0.4	-0.1	0.0	0.5	-0.3	0.1	-0.6	0.1	0.3	-0.0
Seen doctor (GP) for nerves, anxiety, tension or depression	0.0	0.1	0.4	-0.1	0.2	0.2	0.2	0.1	0.3	0.2	-0.6	-0.1
Body fat percentage	0.0	0.2	0.4	0.6	0.3	-0.0	0.0	0.5	-0.5	0.3	0.5	0.3
Heart disease (mother)	0.0	0.1	0.2	-0.4	-0.2	0.1	-0.2	-0.3	-0.1	-0.3	0.2	-0.1
Pulse rate, automated reading	0.0	0.1	0.5	0.0	0.0	-0.1	-0.1	-0.2	-0.0	-0.7	0.1	-0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.0	0.1	0.1	-0.2	0.2	-0.4	0.2	0.2	0.4	-0.1	0.1	-0.3
Medication: Gliclazide	0.0	0.1	0.2	0.2	0.1	0.0	0.1	0.2	-0.1	-0.3	0.4	0.3
Ever smoked	0.0	0.1	0.2	0.2	0.2	-0.4	-0.3	-0.1	-0.5	-0.2	-0.3	-0.1
Deep venous thrombosis (DVT) (self-reported)	0.0	0.0	0.2	0.0	-0.0	-0.2	0.4	0.4	0.2	0.0	0.1	0.2

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