Best TWAS P=4.4e-08 · Best GWAS P=1.97e-09 conditioned to 0.00199
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | PIP4K2A | 0.20 | 0.18 | lasso | 1 | 0.18 | 6.4e-21 | 5.5 | -5.5 | 4.4e-08 | -0.09 | 0.01 | 0.99 | TRUE |
| 2 | GTEx | Artery Tibial | CASC10 | 0.05 | 0.06 | lasso | 4 | 0.02 | 1.3e-02 | 4.4 | 5.3 | 8.7e-08 | 0.55 | 0.26 | 0.47 | TRUE |