TWAS
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Traits
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Traits
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Arm fat-free mass (left)
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chr12:327,421-1,795,687
Best TWAS P=1.52e-08 · Best GWAS P=1.01e-13 conditioned to 4.68e-07
0.4M
0.6M
0.8M
1M
1.2M
1.4M
1.6M
1.8M
0
5
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Esophageal Carcinoma
RAD52
0.25
0.13
blup
66
0.19
1.1e-06
6.6
-5.7
1.5e-08
-0.61
0.00
1.00
TRUE
1
GTEx
Adipose Visceral Omentum
RAD52
0.14
0.07
lasso
3
0.10
1.1e-05
-4.3
-5.6
2.7e-08
-0.44
0.52
0.39
FALSE