[Hub]/) : Traits : Arm fat-free mass (left) :

chr12:27,587,038-29,432,481

Best TWAS P=1.33e-13 · Best GWAS P=9.41e-14 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex CCDC91 0.08 0.06 lasso 6 0.07 9.4e-09 -6.8 6.0 1.8e-09 -0.87 0.16 0.84 FALSE
2 GTEx Artery Aorta RP11-967K21.1 0.07 0.02 lasso 7 0.01 7.9e-02 4.4 6.5 8.3e-11 -0.83 0.07 0.79 FALSE
3 GTEx Cells Transformed fibroblasts CCDC91 0.10 0.10 lasso 5 0.09 5.5e-07 -7.0 -7.0 2.1e-12 0.85 0.10 0.90 FALSE
4 GTEx Cells Transformed fibroblasts RP11-967K21.1 0.07 0.07 lasso 2 0.07 3.7e-06 -7.2 7.4 1.3e-13 -0.96 0.04 0.95 TRUE
5 GTEx Colon Transverse CCDC91 0.11 0.01 lasso 6 0.00 4.6e-01 -6.8 -6.5 6.8e-11 0.80 0.09 0.76 FALSE
6 GTEx Heart Atrial Appendage CCDC91 0.10 0.06 lasso 8 0.04 4.4e-03 -7.0 -6.4 1.3e-10 0.85 0.05 0.89 FALSE
7 GTEx Heart Atrial Appendage RP11-967K21.1 0.08 0.09 lasso 1 0.08 2.3e-04 -7.2 7.2 6.1e-13 -0.91 0.04 0.91 FALSE
8 GTEx Muscle Skeletal RP11-967K21.1 0.04 0.01 lasso 9 0.00 2.9e-01 -6.8 6.4 1.8e-10 -0.90 0.06 0.81 FALSE
9 GTEx Skin Not Sun Exposed Suprapubic CCDC91 0.26 0.05 lasso 15 0.04 4.1e-03 -7.4 -6.4 1.2e-10 0.87 0.04 0.96 FALSE
10 GTEx Skin Sun Exposed Lower leg CCDC91 0.09 0.01 enet 8 0.01 2.6e-02 -7.2 -7.2 5.0e-13 0.85 0.07 0.88 FALSE
11 GTEx Thyroid CCDC91 0.15 0.12 enet 42 0.12 2.9e-09 -7.0 -5.2 2.2e-07 0.81 0.06 0.94 FALSE
12 The Cancer Genome Atlas Breast Invasive Carcinoma CCDC91 0.04 0.04 lasso 3 0.03 1.8e-06 -6.8 -6.8 9.6e-12 0.94 0.12 0.88 FALSE
13 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma CCDC91 0.06 0.02 blup 174 0.04 2.9e-05 3.7 -6.2 6.1e-10 0.79 0.35 0.63 FALSE
14 The Cancer Genome Atlas Lung Adenocarcinoma CCDC91 0.09 0.01 blup 170 0.02 1.0e-03 -7.0 -5.8 7.0e-09 0.75 0.11 0.80 FALSE
15 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma CCDC91 0.09 0.11 lasso 2 0.12 2.3e-05 -6.9 -6.9 6.1e-12 0.91 0.07 0.91 FALSE
16 The Cancer Genome Atlas Thyroid Carcinoma CCDC91 0.40 0.12 blup 175 0.14 4.9e-13 -7.1 -6.2 4.8e-10 0.72 0.05 0.95 FALSE