TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Arm fat-free mass (left)
:
←
→
chr18:12,247,872-13,687,136
Best TWAS P=1.13e-08 · Best GWAS P=8.28e-08 conditioned to 0.069
12.2M
12.4M
12.6M
12.8M
13M
13.2M
13.4M
13.6M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Esophagus Mucosa
SEH1L
0.09
0.02
enet
25
0.03
0.0024
-5.4
5.7
1.1e-08
-0.72
0.00
0.99
TRUE
5
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
SEH1L
0.03
0.01
blup
60
0.01
0.0401
-5.0
5.2
1.9e-07
-0.87
0.00
0.63
FALSE
3
GTEx
Pituitary
SEH1L
0.22
0.07
lasso
6
0.05
0.0206
-5.4
5.2
2.3e-07
-0.89
0.02
0.69
FALSE
1
GTEx
Artery Coronary
RP11-773H22.4
0.18
0.11
lasso
5
0.06
0.0063
-5.4
5.2
2.4e-07
-0.97
0.01
0.77
FALSE
4
The Cancer Genome Atlas
Colon Adenocarcinoma
CEP192
0.06
0.05
blup
84
0.04
0.0015
4.2
5.1
3.1e-07
-0.59
0.20
0.36
FALSE