[Hub]/) : Traits : Arm fat-free mass (left) : ← →

chr17:42,041,273-43,913,030

Best TWAS P=5.59e-14 · Best GWAS P=1.02e-15 conditioned to 0.384

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
30	GTEx	Thyroid	ACBD4	0.20	0.16	enet	23	0.15	1.2e-11	-6.3	-7.5	5.6e-14	0.51	1.00	0.00	TRUE
5	GTEx	Artery Coronary	NMT1	0.13	0.06	enet	7	0.11	1.5e-04	5.2	-6.1	1.1e-09	0.53	0.13	0.21	TRUE
14	GTEx	Breast Mammary Tissue	KANSL1	0.31	0.00	enet	9	0.11	2.6e-06	2.2	-5.3	1.4e-07	0.08	0.00	0.01	TRUE
45	The Cancer Genome Atlas	Thyroid Carcinoma	HEXIM1	0.05	0.05	blup	47	0.04	8.5e-05	-8.0	7.4	1.1e-13	-0.84	0.00	1.00	FALSE
2	GTEx	Adipose Subcutaneous	ACBD4	0.10	0.06	enet	8	0.06	1.8e-05	-6.3	-7.2	6.2e-13	0.52	0.52	0.36	FALSE
25	GTEx	Nerve Tibial	ACBD4	0.21	0.10	lasso	5	0.11	4.2e-08	-5.8	-7.1	1.3e-12	0.47	0.92	0.07	FALSE
28	GTEx	Skin Sun Exposed Lower leg	ACBD4	0.06	0.05	lasso	4	0.02	3.8e-03	5.6	-7.1	1.3e-12	0.33	0.19	0.08	FALSE
4	GTEx	Artery Aorta	DCAKD	0.22	0.16	enet	26	0.19	1.1e-10	-3.9	6.6	4.1e-11	-0.46	0.92	0.07	FALSE
7	GTEx	Artery Tibial	ACBD4	0.10	0.09	lasso	2	0.08	4.8e-07	-6.3	-6.3	2.4e-10	0.58	0.80	0.13	FALSE
33	YFS	Blood	NMT1	0.02	0.01	lasso	6	0.01	5.0e-03	6.0	-6.3	3.3e-10	0.37	0.29	0.02	FALSE
37	The Cancer Genome Atlas	Brain Lower Grade Glioma	ACBD4	0.08	0.04	enet	9	0.04	6.9e-06	-6.3	-6.3	3.9e-10	0.50	0.94	0.01	FALSE
36	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	DCAKD	0.07	0.07	lasso	4	0.07	1.4e-08	-5.1	6.2	7.3e-10	-0.56	0.03	0.97	FALSE
46	The Cancer Genome Atlas	Thyroid Carcinoma	PLCD3	0.24	0.16	lasso	5	0.20	2.8e-19	5.4	6.2	7.5e-10	-0.15	1.00	0.00	FALSE
29	GTEx	Stomach	DCAKD	0.29	0.17	enet	25	0.20	9.4e-10	-3.9	6.1	1.2e-09	-0.48	0.57	0.42	FALSE
41	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	NMT1	0.23	0.08	blup	82	0.12	1.1e-05	3.9	-6.0	1.6e-09	0.55	0.06	0.89	FALSE
10	GTEx	Brain Cerebellar Hemisphere	CTD-2020K17.4	0.23	0.02	enet	20	0.11	1.1e-03	-5.8	-6.0	2.6e-09	0.46	0.03	0.16	FALSE
19	GTEx	Esophagus Gastroesophageal Junction	NMT1	0.24	0.21	lasso	4	0.22	2.8e-08	3.8	-6.0	2.7e-09	0.54	0.68	0.27	FALSE
42	The Cancer Genome Atlas	Prostate Adenocarcinoma	ACBD4	0.04	0.01	enet	7	0.03	2.2e-04	4.1	-5.9	3.0e-09	0.44	0.09	0.13	FALSE
43	The Cancer Genome Atlas	Prostate Adenocarcinoma	LOC644172	0.15	0.01	blup	77	0.06	1.0e-06	6.0	5.9	3.4e-09	-0.40	0.19	0.29	FALSE
3	GTEx	Adrenal Gland	PLEKHM1	0.21	0.00	enet	20	0.08	1.0e-03	4.1	5.8	8.8e-09	-0.13	0.08	0.14	FALSE
39	The Cancer Genome Atlas	Lung Adenocarcinoma	NMT1	0.04	0.00	blup	81	0.01	1.9e-02	-4.0	-5.7	1.0e-08	0.27	0.03	0.67	FALSE
21	GTEx	Esophagus Mucosa	ACBD4	0.14	0.10	lasso	4	0.10	4.5e-07	5.4	-5.7	1.1e-08	0.13	0.59	0.08	FALSE
23	GTEx	Muscle Skeletal	PLCD3	0.18	0.10	enet	8	0.10	1.7e-10	5.4	5.7	1.3e-08	-0.12	1.00	0.00	FALSE
32	YFS	Blood	HEXIM2	0.02	0.01	bslmm	279	0.01	1.0e-05	5.2	-5.7	1.6e-08	0.61	0.37	0.61	FALSE
38	The Cancer Genome Atlas	Brain Lower Grade Glioma	LOC644172	0.04	0.00	enet	15	0.02	4.0e-03	-8.0	5.6	1.7e-08	-0.60	0.00	0.76	FALSE
1	GTEx	Adipose Subcutaneous	DCAKD	0.21	0.09	lasso	6	0.14	6.1e-12	5.2	5.6	2.0e-08	-0.35	1.00	0.00	FALSE
12	GTEx	Brain Cerebellum	ACBD4	0.40	0.06	lasso	8	0.17	1.0e-05	5.6	-5.6	2.3e-08	0.27	0.09	0.14	FALSE
24	GTEx	Muscle Skeletal	DCAKD	0.12	0.06	enet	16	0.07	9.9e-08	-5.1	5.6	2.3e-08	-0.54	0.87	0.13	FALSE
26	GTEx	Skin Not Sun Exposed Suprapubic	DCAKD	0.30	0.21	lasso	6	0.20	5.0e-11	-5.1	5.6	2.3e-08	-0.58	1.00	0.00	FALSE
9	GTEx	Brain Cerebellar Hemisphere	ACBD4	0.43	0.12	lasso	8	0.18	1.7e-05	-5.8	-5.6	2.6e-08	0.37	0.11	0.44	FALSE
35	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	LOC644172	0.19	-0.01	blup	81	0.03	1.3e-02	2.0	5.5	2.8e-08	-0.47	0.02	0.56	FALSE
44	The Cancer Genome Atlas	Testicular Germ Cell Tumors	LOC644172	0.20	0.01	enet	12	0.06	4.5e-03	-3.3	5.4	7.8e-08	-0.47	0.06	0.09	FALSE
40	The Cancer Genome Atlas	Lung Adenocarcinoma	PLCD3	0.04	0.01	blup	64	0.01	2.3e-02	5.4	-5.3	1.0e-07	0.27	0.05	0.08	FALSE
34	The Cancer Genome Atlas	Breast Invasive Carcinoma	LOC644172	0.14	0.07	enet	10	0.12	1.2e-23	2.0	5.3	1.1e-07	-0.35	1.00	0.00	FALSE
6	GTEx	Artery Tibial	NMT1	0.11	0.09	lasso	5	0.10	6.3e-08	-4.1	-5.3	1.4e-07	0.36	0.99	0.00	FALSE
27	GTEx	Skin Sun Exposed Lower leg	DCAKD	0.33	0.20	enet	30	0.31	2.4e-26	-3.9	5.3	1.4e-07	-0.27	1.00	0.00	FALSE
20	GTEx	Esophagus Gastroesophageal Junction	DCAKD	0.42	0.36	lasso	7	0.37	3.8e-14	-5.1	5.2	1.6e-07	-0.58	0.96	0.04	FALSE
15	GTEx	Breast Mammary Tissue (Male)	DCAKD	0.36	0.29	lasso	8	0.33	1.4e-08	-3.9	5.2	1.8e-07	-0.58	0.42	0.44	FALSE
8	GTEx	Artery Tibial	HEXIM1	0.13	0.08	lasso	2	0.05	1.8e-04	5.2	5.2	2.2e-07	-0.58	0.85	0.11	FALSE
17	GTEx	Cells Transformed fibroblasts	HEXIM1	0.11	0.10	lasso	2	0.08	1.6e-06	5.2	5.2	2.4e-07	-0.58	0.78	0.16	FALSE
31	METSIM	Adipose	C17orf104	0.05	0.02	bslmm	404	0.04	4.2e-06	4.5	-5.2	2.4e-07	0.11	0.91	0.00	FALSE
18	GTEx	Colon Transverse	DCAKD	0.28	0.18	lasso	8	0.26	1.5e-12	-3.9	5.2	2.5e-07	-0.41	0.99	0.01	FALSE
11	GTEx	Brain Cerebellum	DCAKD	0.40	0.06	enet	20	0.24	1.4e-07	-3.9	5.1	2.7e-07	-0.39	0.80	0.06	FALSE
22	GTEx	Heart Left Ventricle	DCAKD	0.17	0.17	lasso	3	0.17	2.3e-09	-3.9	5.1	2.8e-07	-0.55	0.97	0.03	FALSE
16	GTEx	Cells Transformed fibroblasts	PLCD3	0.23	0.04	lasso	5	0.08	1.3e-06	2.1	5.1	3.0e-07	-0.48	0.95	0.01	FALSE
13	GTEx	Brain Hippocampus	CCDC43	0.23	0.09	enet	9	0.16	1.8e-04	-5.8	5.1	3.1e-07	-0.46	0.05	0.30	FALSE