Best TWAS P=9.06e-16 · Best GWAS P=1.26e-22 conditioned to 1.88e-06
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Tibial | ZFP64 | 0.10 | 0.03 | lasso | 4 | 0.06 | 3.4e-05 | 2.9 | 8.0 | 9.1e-16 | -0.71 | 0.22 | 0.48 | TRUE |
2 | GTEx | Cells Transformed fibroblasts | ZFP64 | 0.09 | 0.09 | enet | 5 | 0.09 | 1.9e-07 | -2.9 | 6.7 | 2.8e-11 | -0.44 | 0.64 | 0.29 | TRUE |
3 | YFS | Blood | TSHZ2 | 0.10 | 0.03 | bslmm | 798 | 0.07 | 2.8e-22 | -7.1 | 6.0 | 2.2e-09 | -0.59 | 0.01 | 0.99 | FALSE |