Best TWAS P=2.74e-08 · Best GWAS P=9.09e-08 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | METSIM | Adipose | ARFGEF2 | 0.04 | 0.03 | lasso | 12 | 0.02 | 9.8e-05 | 5.3 | -5.6 | 2.7e-08 | -0.96 | 0.02 | 0.98 | TRUE |
| 2 | NTR | Blood | SNORD12B | 0.03 | 0.05 | lasso | 8 | 0.05 | 1.9e-14 | 5.3 | -5.5 | 4.6e-08 | -0.98 | 0.01 | 0.99 | FALSE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | ARFGEF2 | 0.05 | 0.04 | lasso | 5 | 0.05 | 3.2e-06 | 5.0 | -5.3 | 9.1e-08 | -0.87 | 0.01 | 0.99 | FALSE |
| 4 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | C20orf199 | 0.05 | 0.06 | lasso | 4 | 0.06 | 1.0e-04 | 5.3 | 5.3 | 1.0e-07 | 1.00 | 0.00 | 0.96 | FALSE |