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Traits
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Traits
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Arm fat-free mass (left)
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chr3:84,317,575-86,808,226
Best TWAS P=6.4e-22 · Best GWAS P=9.89e-22 conditioned to 0.000718
84.5M
85M
85.5M
86M
86.5M
0
5
10
15
20
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
The Cancer Genome Atlas
Lung Adenocarcinoma
CADM2
0.08
0.04
lasso
4
0.05
2.1e-06
9.3
9.6
6.4e-22
0.77
0.11
0.88
TRUE
4
The Cancer Genome Atlas
Lung Squamous Cell Carcinoma
CADM2
0.05
0.03
lasso
3
0.04
5.0e-05
9.3
9.6
7.2e-22
0.81
0.08
0.92
FALSE
1
METSIM
Adipose
CADM2
0.05
0.06
lasso
10
0.06
1.3e-09
7.1
7.7
1.7e-14
0.63
0.90
0.10
FALSE
2
The Cancer Genome Atlas
Brain Lower Grade Glioma
CADM2
0.06
0.00
blup
339
0.00
2.7e-01
-5.9
-7.1
1.2e-12
-0.39
0.06
0.14
FALSE
5
The Cancer Genome Atlas
Pheochromocytoma and Paraganglioma
CADM2
0.14
0.05
blup
339
0.09
2.7e-04
9.0
6.0
2.1e-09
0.76
0.10
0.60
FALSE