[Hub]/) : Traits : Arm fat-free mass (left) :

chr3:55,894,951-57,412,804

Best TWAS P=4.84e-13 · Best GWAS P=1.48e-10 conditioned to 0.0974

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous FAM208A 0.12 0.09 enet 11 0.12 1.1e-09 -3.4 5.5 4.3e-08 -0.82 0.03 0.97 FALSE
2 GTEx Cells Transformed fibroblasts FAM208A 0.10 0.00 lasso 4 0.00 1.3e-01 -6.3 6.0 1.4e-09 -0.82 0.01 0.96 FALSE
3 YFS Blood CCDC66 0.11 0.09 lasso 8 0.11 6.0e-34 -5.2 -5.2 1.5e-07 0.53 0.83 0.16 FALSE
4 The Cancer Genome Atlas Breast Invasive Carcinoma CCDC66 0.09 0.03 lasso 8 0.05 4.2e-11 -4.5 -6.5 6.2e-11 0.54 0.23 0.77 FALSE
5 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma CCDC66 0.05 0.05 blup 56 0.06 1.0e-07 -6.3 -7.1 9.7e-13 0.79 0.00 1.00 FALSE
6 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma C3orf63 0.03 0.01 enet 4 0.01 1.3e-02 -6.3 5.8 6.1e-09 -0.89 0.01 0.88 FALSE
7 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma CCDC66 0.09 0.05 blup 56 0.06 5.3e-07 -5.2 -5.3 1.3e-07 0.69 0.55 0.45 FALSE
8 The Cancer Genome Atlas Brain Lower Grade Glioma CCDC66 0.16 0.13 enet 12 0.16 3.1e-17 -5.2 -5.3 9.6e-08 0.34 0.67 0.33 FALSE
9 The Cancer Genome Atlas Lung Adenocarcinoma CCDC66 0.05 0.06 blup 56 0.05 9.7e-07 -6.3 -7.2 4.8e-13 0.73 0.00 1.00 TRUE
10 The Cancer Genome Atlas Lung Squamous Cell Carcinoma CCDC66 0.03 0.03 blup 56 0.03 9.6e-05 -4.5 -5.8 5.0e-09 0.51 0.31 0.32 FALSE
11 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma CCDC66 0.08 0.01 blup 56 0.07 7.2e-04 -5.2 -5.3 1.1e-07 0.32 0.11 0.11 FALSE
12 The Cancer Genome Atlas Prostate Adenocarcinoma CCDC66 0.15 0.10 enet 11 0.13 7.3e-14 -4.5 -5.6 2.2e-08 0.48 0.79 0.21 FALSE
13 The Cancer Genome Atlas Stomach Adenocarcinoma CCDC66 0.05 0.01 blup 57 0.02 8.4e-03 -4.5 -6.0 2.7e-09 0.55 0.07 0.53 FALSE