Best TWAS P=2.25e-16 · Best GWAS P=6e-14 conditioned to 0.00396
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Testis | HMCES | 0.75 | 0.56 | lasso | 8 | 0.55 | 8.4e-29 | 5.6 | 5.7 | 1.5e-08 | -0.15 | 1.00 | 0.00 | FALSE |
| 2 | YFS | Blood | H1FX | 0.02 | 0.01 | lasso | 3 | 0.01 | 1.4e-03 | -6.7 | 6.7 | 2.6e-11 | -0.84 | 0.08 | 0.56 | FALSE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | H1FX | 0.02 | 0.02 | lasso | 5 | 0.03 | 6.5e-07 | 5.9 | 8.1 | 5.0e-16 | -0.62 | 0.10 | 0.88 | FALSE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | H1FX | 0.02 | 0.00 | blup | 36 | 0.00 | 5.1e-01 | -7.5 | 8.2 | 2.3e-16 | -0.65 | 0.00 | 0.68 | TRUE |