TWAS hub - HMCES

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Colon Transverse	0.182	0.071	0.0014	0.005	NA	0.058	NA	0.034	1.7e-01	NA	9.3e-04	NA	9.2e-03
2	GTEx	Testis	0.752	0.041	0.0000	0.563	NA	0.498	NA	0.551	1.1e-29	NA	5.2e-25	NA	8.4e-29

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Past tobacco smoking	8.5	15.5	17.3	-3.7	-4.2
Ever smoked	7.9	13.9	14.9	3.9	3.6
Smoking status: Previous	7.1	10.6	14.4	2.6	3.8
Leg fat-free mass (right)	5.7	30.4	57.6	1.8	7.6
Leg predicted mass (right)	5.7	30.3	57.0	1.9	7.5
Leg fat-free mass (left)	5.5	29.0	55.4	1.6	7.4
Leg predicted mass (left)	5.4	28.6	54.6	1.6	7.4
Peak expiratory flow (PEF)	5.1	11.9	23.0	0.9	4.8
Smoking Status	5.0	11.9	13.7	3.7	3.2
Waist Hip Ratio (WHR)	4.8	21.7	35.6	6.0	-2.8
Other serious medical condition/disability diagnosed by doctor	4.8	6.2	9.9	3.1	1.6
Commuting to job workplace: Walk	4.8	5.1	10.2	0.1	3.2
Whole body water mass	4.6	26.0	50.1	1.4	7.1
Whole body fat-free mass	4.5	26.0	49.8	1.5	7.1
Basal metabolic rate	4.5	25.1	47.9	1.5	6.9
Schizophrenia (2014)	4.4	9.8	14.4	-2.3	-3.8
Trunk fat-free mass	4.2	23.9	46.1	1.3	6.8
Supplements: Vitamin C	4.2	5.0	10.0	3.2	0.0
Trunk predicted mass	4.1	23.3	45.2	1.2	6.7
Number of operations (self-reported)	4.0	5.9	7.5	2.7	2.1
Mouth/teeth dental problems: Mouth ulcers	3.9	6.2	11.6	3.4	0.9
Comparative height size at age 10	3.8	20.8	41.5	0.4	6.4
HbA1C	3.7	4.1	8.3	0.0	-2.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	3.7	4.3	8.2	2.9	-0.7
Arm fat-free mass (right)	3.6	18.7	35.5	1.3	6.0
Weight	3.5	17.4	32.4	1.6	5.7
Irritability	3.5	6.0	11.6	3.4	0.6
Forced expiratory volume in 1-second (FEV1)	3.4	11.6	23.1	-0.2	4.8
Standing height	3.4	33.6	65.3	1.4	8.1
Arm predicted mass (right)	3.4	17.6	34.1	1.0	5.8
Forced expiratory volume in 1-second (FEV1), predicted	3.4	7.0	14.0	0.3	3.7
Arm predicted mass (left)	3.4	17.2	33.4	1.0	5.8
Arm fat-free mass (left)	3.3	16.7	32.0	1.2	5.7
Townsend deprivation index at recruitment	3.2	4.5	5.2	2.0	2.3
Diabetes diagnosed by doctor	3.2	5.3	5.8	2.2	-2.4
Miserableness	3.2	5.6	8.1	2.9	1.7
Bipolar Disorder (2011)	3.1	3.0	5.9	0.0	-2.4
Height	3.1	60.0	116.6	1.8	10.8
Diabetes (father)	3.1	3.8	4.8	2.2	-1.7
Neuroticism score	3.0	6.3	12.6	3.5	0.3
Schizophrenia (2018)	2.9	6.1	7.4	-2.2	-2.7
Diabetes (self-reported)	2.9	4.4	6.2	1.6	-2.5
Type 2 Diabetes (T2D) (2012)	2.8	3.2	5.8	0.7	-2.4
Forced vital capacity (FVC)	2.8	10.9	21.3	-0.7	4.6
Medication: Ramipril	2.8	3.6	6.4	-0.9	-2.5
Neuroticism	2.7	6.5	12.4	3.5	0.9
Hand grip strength (left)	2.7	7.0	14.0	0.2	3.7
Bipolar Disorder or Schizophrenia	2.6	6.3	10.4	-1.4	-3.2
Hip circumference	2.6	11.2	22.1	-0.6	4.7
Hand grip strength (right)	2.5	6.7	13.0	0.7	3.6
Hair/balding pattern: Pattern 2	2.5	3.2	6.1	-0.5	-2.5
Alcohol drinker status: Previous	2.5	2.8	5.4	2.3	0.5
Impedance of leg (right)	2.4	11.8	21.3	-1.5	-4.6
Sitting height	2.4	17.2	30.4	2.0	5.5
Impedance of leg (left)	2.4	11.4	21.8	-1.0	-4.7
Depression (self-reported)	2.4	2.8	4.8	2.2	0.9
Hearing difficulty/problems: Yes	2.3	3.6	4.2	2.1	1.7
Medication: Simvastatin	2.3	3.4	4.1	2.0	-1.6
Worry too long after embarrassment	2.3	3.9	5.9	2.4	1.4
Illness, injury, bereavement, stress in last 2 years	2.3	2.8	5.4	-2.3	0.4
Ever had stillbirth, spontaneous miscarriage or termination	2.3	2.4	4.8	2.2	-0.1
Commuting to job workplace: Public transport	2.3	2.7	4.7	0.8	-2.2
Major Depression (MDD)	2.2	2.6	5.2	2.3	-0.2
Medication: Metformin	2.2	3.1	5.2	0.9	-2.3
Depressed Affect (Nagel 2018)	2.1	4.5	4.9	2.2	2.0
Supplements: Zinc	2.1	2.3	2.3	-1.5	-1.5
Chronic bronchitis/emphysema (father)	2.1	2.4	4.5	2.1	0.6
Hearing difficulty/problems with background noise	2.1	3.3	3.5	1.8	1.9
Birth weight	2.1	4.5	5.9	2.4	1.8
Hearing aid user	2.1	2.4	4.7	-0.2	2.2
Age at First Birth	2.0	2.9	4.0	-2.0	-1.3
Pack years adult smoking proportion	2.0	3.1	4.2	2.1	-1.4
Maternal smoking around birth	2.0	2.8	5.4	0.5	2.3
Fed-up feelings	2.0	3.7	4.0	1.8	2.0
Serious illness, injury or assault of a close relative in last 2 years	2.0	2.4	4.1	0.7	-2.0
Supplements: Glucosamine	1.9	2.5	3.5	1.2	1.9
Diverticular disease/diverticulitis (self-reported)	1.9	2.2	2.9	1.2	-1.7
Tense / ‘highly strung’	1.9	3.2	5.8	2.4	-0.8
Long-standing illness, disability or infirmity	1.9	2.9	5.2	2.3	0.8
Trunk fat mass	1.8	7.6	13.5	1.3	3.7
Arm fat mass (left)	1.8	7.4	13.8	1.0	3.7
Medication: Blood pressure	1.8	3.3	6.6	0.2	-2.6
Serious illness, injury or assault to yourself	1.7	2.0	3.8	1.9	-0.5
Forced expiratory volume in 1-second (FEV1), Best measure	1.7	5.6	10.8	0.5	3.3
Arm fat mass (right)	1.7	7.1	12.8	1.1	3.6
Medication for pain relief, constipation, heartburn	1.7	2.9	5.7	-2.4	0.2
Whole body fat mass	1.7	7.1	12.5	1.3	3.5
Illnesses of father: None of the above (group 1)	1.7	2.1	2.2	-1.4	1.5
Age started oral contraceptive pill	1.7	2.2	2.4	-1.4	-1.6
Pack years of smoking	1.7	2.5	3.1	1.8	-1.4
Waist circumference	1.6	5.9	6.4	2.3	2.5
Frequency of tenseness / restlessness in last 2 weeks	1.6	2.4	4.8	2.2	-0.3
Worrier / anxious feelings	1.6	3.1	6.1	2.5	-0.2
Had major operations	1.6	1.9	2.6	1.1	1.6
Lupus	1.5	2.3	3.2	-1.8	-1.2
Heel T-Score	1.5	11.6	21.2	-1.4	-4.6
Noisy workplace	1.5	1.8	2.9	0.9	1.7
Medication: Amlodipine	1.5	2.1	2.1	1.4	-1.4
Chronic bronchitis/emphysema (mother)	1.5	1.7	2.1	1.5	1.1
Medication: Gliclazide	1.5	1.7	2.0	1.4	-1.2
Ever taken oral contraceptive pill	1.5	1.7	2.8	1.7	-0.7
Medication: Atorvastatin	1.5	1.9	3.1	1.8	-0.9
Had menopause	1.4	1.8	3.5	0.2	-1.9
Forced vital capacity (FVC), Best measure	1.4	5.0	10.0	0.1	3.2
Mood swings	1.4	2.5	4.4	2.1	0.8
Guilty feelings	1.4	2.1	4.0	2.0	0.5
Illnesses of father: High blood pressure	1.4	1.7	2.9	1.7	-0.7
Vascular/heart problems diagnosed by doctor	1.4	3.7	6.9	-0.7	2.6
Breast Cancer	1.3	3.1	6.1	-0.1	-2.5
BMI	1.3	7.6	13.1	1.4	3.6
Financial difficulties in last 2 years	1.3	1.7	2.2	1.1	1.5
Mouth/teeth dental problems	1.3	2.0	3.5	-1.9	0.7
Medication: Cholesterol lowering	1.3	2.0	2.4	1.6	-1.2
Illnesses of siblings: Diabetes	1.3	1.7	1.8	1.3	-1.2
Medication for cholesterol	1.3	1.9	2.6	-1.1	1.6
Average weekly champagne plus white wine intake	1.3	1.8	1.9	1.4	-1.3
Financial situation satisfaction	1.3	1.6	3.1	-0.2	1.8
Medication: Lisinopril	1.3	1.7	2.9	-0.7	-1.7
Cholesterol lowering medication	1.3	2.0	2.1	1.4	-1.4
Pain experienced in last month	1.3	2.1	4.2	-2.1	0.1
Type 2 Diabetes (T2D) (2018)	1.2	2.3	3.2	1.2	-1.8
Eye problems/disorders: Diabetes related eye disease	1.2	1.3	1.6	1.2	-1.1
Average weekly fortified wine intake	1.2	1.4	2.8	1.7	-0.1
Reason for reducing amount of alcohol drunk: Health precaution	1.2	1.4	1.8	0.9	-1.4
Qualifications: College or University degree	1.2	3.9	7.4	-0.6	-2.7
Neck or shoulder pain in last month	1.2	1.7	2.8	1.7	0.8
Alcohol intake frequency.	1.2	2.9	3.7	1.9	-1.4
Risk taking	1.2	1.8	2.2	1.5	-1.1
Bipolar Disorder (2018)	1.1	1.7	3.2	-0.4	-1.8
Neuroticism (Nagel 2018)	1.1	2.6	4.3	2.1	1.0
Medication for hormone replacement therapy	1.1	1.3	1.3	1.1	1.1
Frequency of unenthusiasm / disinterest in last 2 weeks	1.1	1.5	2.9	1.7	0.4
Qualifications: CSEs or equivalent	1.1	1.5	2.2	-0.9	1.5
Hayfever/allergic rhinitis (self-reported)	1.1	1.4	1.7	1.1	-1.3
Comparative body size at age 10	1.1	3.2	4.6	1.3	2.1
Number of children fathered	1.1	1.2	1.6	-0.9	1.3
Suffer from ‘nerves’	1.1	1.8	3.0	0.7	-1.7
Hypertension (Self-reported)	1.1	3.1	4.4	1.4	-2.1
Leg fat mass (left)	1.1	4.4	7.3	1.2	2.7
Neuroticism (2016)	1.0	1.5	3.0	1.7	0.2
Ulcerative Colitis	1.0	1.4	2.7	-1.6	-0.4
High blood pressure	1.0	2.8	4.4	1.1	-2.1
Hair/balding pattern: Pattern 3	1.0	1.4	2.8	-0.2	1.7
Seen a psychiatrist for nerves, anxiety, tension or depression	1.0	1.3	1.4	1.2	1.0
Leg fat mass (right)	1.0	4.0	7.0	1.0	2.6
Commuting to job workplace: Car/motor vehicle	1.0	1.2	2.2	-1.5	-0.4
Medication: Aspirin	1.0	1.3	2.1	1.4	-0.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.0	1.1	1.2	1.0	1.1
Ever had prostate specific antigen (PSA) test	1.0	1.2	1.9	-0.7	-1.4
Primary Biliary Cirrhosis	0.9	1.3	2.1	0.7	-1.4
Cardiovascular Disease	0.9	3.0	4.1	1.4	-2.0
Current tobacco smoking	0.9	1.5	3.0	1.7	0.2
Bilateral oophorectomy (both ovaries removed)	0.9	1.0	1.6	1.3	0.7
Body mass index (BMI)	0.9	3.6	5.9	1.2	2.4
Heel bone mineral density (BMD) T-score, automated (right)	0.9	2.0	3.9	0.2	-2.0
Illnesses of siblings	0.9	1.3	1.8	-1.3	0.9
Alcohol intake versus 10 years previously	0.9	1.3	1.6	1.3	1.0
Pulse wave reflection index	0.9	1.1	2.1	-1.5	0.1
Ever highly irritable/argumentative for 2 days	0.9	1.1	1.5	-0.8	1.2
Medication: Seretide 50 evohaler	0.9	1.0	2.0	1.4	-0.2
Tinnitus: Yes, now most or all of the time	0.9	1.0	1.5	0.7	1.2
Average weekly beer plus cider intake	0.9	1.3	1.9	-1.4	0.9
Ever depressed for a whole week	0.9	1.2	1.8	1.3	0.7
Medication: Omeprazole (e.g. Zanprol)	0.9	1.2	2.2	1.5	0.4
Heart attack/myocardial infarction (self-reported)	0.9	1.2	1.2	-1.1	-1.1
Impedance of whole body	0.9	4.5	7.4	-1.3	-2.7
Coronary Artery Disease (CAD)	0.8	1.0	1.7	-0.4	1.3
Systolic Blood Pressure	0.8	3.9	6.5	-2.5	-1.2
Severe depression (siblings)	0.8	0.9	1.8	1.4	0.2
Heel bone mineral density (BMD) T-score, automated (left)	0.8	1.9	3.3	0.7	-1.8
Frequency of tiredness / lethargy in last 2 weeks	0.8	1.3	2.6	-0.3	1.6
Length of working week for main job	0.8	0.9	1.8	1.3	0.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.8	1.3	2.1	1.5	-0.7
Hair/balding pattern: Pattern 4	0.8	1.8	3.1	1.8	0.8
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.8	1.0	1.5	-0.7	1.2
Overall health rating	0.8	1.6	2.6	1.6	-0.8
Qualifications: NVQ or HND or HNC or equivalent	0.8	1.0	1.4	0.7	1.2
Ever had bowel cancer screening	0.8	0.9	0.9	1.0	-1.0
Eye problems/disorders: Cataract	0.8	0.9	1.4	-1.2	-0.6
Smoking status: Current	0.8	1.3	2.7	1.6	0.1
Number of self-reported non-cancer illnesses	0.8	1.4	2.7	1.7	-0.3
Supplements: Calcium	0.8	0.8	1.0	-1.0	-0.8
Depression (Nagel 2018)	0.7	1.0	1.3	1.2	-0.8
Crohns Disease (2012)	0.7	1.2	2.3	0.2	-1.5
Number of incorrect matches in round	0.7	1.2	2.3	-0.3	-1.5
Falls in the last year	0.7	0.9	1.6	-0.6	-1.3
Medication: Paracetamol	0.7	1.2	2.4	0.0	1.5
Medication for cholesterol, blood pressure or diabetes	0.7	1.1	1.9	-0.6	1.4
High blood pressure (siblings)	0.7	1.0	1.4	1.2	-0.8
Exposure to tobacco smoke outside home	0.7	0.9	0.9	1.0	-0.9
Medication: Omeprazole	0.7	0.8	1.6	1.3	0.2
Family relationship satisfaction	0.7	0.8	1.6	0.1	1.3
Arm fat percentage (left)	0.7	2.7	4.9	0.7	2.2
Mineral and other dietary supplements	0.7	0.9	1.1	-1.0	-0.9
Medication: Paracetamol	0.7	1.0	2.0	-0.2	1.4
Diastolic blood pressure, automated reading	0.7	2.2	2.4	-1.6	1.4
Intelligence (Savage-Jansen 2018)	0.6	1.7	3.4	-0.1	1.9
Worry (Nagel 2018)	0.6	1.2	1.6	1.3	-0.9
Alzheimer’s Disease (in mother)	0.6	0.7	1.2	-0.5	-1.1
Alzheimer’s Disease (in father)	0.6	0.6	1.0	1.0	0.6
Prostate Cancer	0.6	0.9	1.0	-0.8	-1.0
Body Mass Index (BMI) (2010)	0.6	0.8	1.6	-0.3	1.2
Rheumatoid Arthritis	0.6	0.8	1.0	1.0	-0.8
Systolic blood pressure, automated reading	0.6	1.7	2.9	-1.7	-0.8
Trunk fat percentage	0.6	2.2	4.0	0.7	2.0
Taking other prescription medications	0.6	0.9	1.1	1.0	-0.8
Had other major operations	0.6	0.7	0.7	0.8	0.9
Heart attack	0.6	0.8	0.8	-0.9	-0.9
Happiness	0.6	0.8	1.4	0.3	1.2
Lung cancer (father)	0.6	0.7	1.2	1.1	0.5
Exposure to tobacco smoke at home	0.6	0.7	0.8	0.9	0.7
Qualifications: O levels/GCSEs or equivalent	0.6	1.0	1.9	-0.3	1.4
Number of full brothers	0.6	0.8	1.1	1.1	0.7
Medication: Aspirin	0.6	0.8	1.5	1.2	-0.4
Supplements: Fish oil (including cod liver oil)	0.6	0.8	1.5	-0.3	1.2
Heart disease (siblings)	0.6	0.8	1.6	1.2	-0.0
Alzheimer’s Disease (including proxy)	0.5	0.7	1.2	0.3	-1.1
Sensitivity / hurt feelings	0.5	0.9	1.5	1.2	0.5
Ever used hormone-replacement therapy (HRT)	0.5	0.6	1.0	0.5	-1.0
Nervous feelings	0.5	0.9	1.3	0.8	-1.1
Arm fat percentage (right)	0.5	2.0	3.2	0.9	1.8
Number of live births	0.5	0.7	1.0	-1.0	0.6
Prospective memory result	0.5	0.6	0.8	-0.7	-0.9
Birth weight of first child	0.5	1.0	1.9	1.4	-0.2
Age at first live birth	0.5	0.8	1.6	-1.3	0.1
Knee pain experienced in last month	0.5	0.8	1.5	1.2	-0.2
Qualifications: nursing, teaching	0.5	0.7	1.5	-1.2	0.1
Eye problems/disorders: Glaucoma	0.5	0.6	1.2	-1.1	0.2
High cholesterol (Self-reported)	0.5	0.8	0.9	0.9	-1.0
Unable to work because of sickness or disability	0.5	0.7	0.7	0.8	0.8
Ulcerative Colitis (UC)	0.4	0.7	1.2	-0.4	-1.1
Ovarian Cancer	0.4	0.5	0.8	0.9	-0.5
Mean Putamen Volume	0.4	0.5	1.0	-0.1	1.0
Hypothyroidism (self reported)	0.4	0.9	1.7	1.3	-0.3
Lung FEV1/FVC ratio	0.4	2.3	4.2	2.0	0.6
Lung FVC	0.4	2.2	4.2	-2.0	0.5
Frequency of depressed mood in last 2 weeks	0.4	0.5	1.0	1.0	0.2
Hayfever, allergic rhinitis or eczema	0.4	0.8	1.4	-1.2	-0.5
Mouth/teeth dental problems: Dentures	0.4	0.6	1.2	1.1	0.2
Breastfed as a baby	0.4	0.5	0.9	-0.3	-0.9
Health satisfaction	0.4	0.5	0.9	0.3	0.9
Eye problems/disorders: None of the above	0.4	0.5	0.9	0.9	0.2
Medication: Ibuprofen	0.4	0.5	1.0	1.0	-0.2
Pulse rate, automated reading	0.4	1.2	1.9	0.6	-1.4
Age at last live birth	0.4	0.6	0.9	-0.4	1.0
Breast cancer (self-reported)	0.4	0.5	1.0	-1.0	-0.0
Schizophrenia vs Biploar Disorder	0.3	0.5	0.8	0.9	0.3
Relative age of first facial hair	0.3	0.7	1.0	-0.6	-1.0
Age when periods started (menarche)	0.3	0.8	1.1	0.7	-1.0
Stomach or abdominal pain in last month	0.3	0.4	0.8	0.9	0.2
Medication: Levothyroxine sodium	0.3	0.4	0.9	-0.9	-0.1
Pain all over the body in last month	0.3	0.3	0.5	0.4	-0.7
Pulse rate	0.3	0.4	0.6	0.5	-0.8
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.4	0.8	0.9	0.1
Illnesses of mother	0.3	0.4	0.7	-0.3	0.8
Mouth/teeth dental problems: Bleeding gums	0.3	0.4	0.6	-0.4	-0.8
Glaucoma (self-reported)	0.3	0.4	0.7	-0.8	-0.3
Body fat percentage	0.3	1.4	2.3	0.6	1.5
Pulse wave peak to peak time	0.3	0.4	0.7	0.2	0.8
Mouth/teeth dental problems: Loose teeth	0.3	0.3	0.6	-0.3	-0.7
Medication: Blood pressure	0.3	0.5	0.9	-0.1	-0.9
Medication: Allopurinol	0.3	0.3	0.7	0.1	-0.8
Leg pain on walking	0.3	0.3	0.6	0.2	0.8
Average weekly red wine intake	0.3	0.5	0.6	-0.8	0.6
Friendships satisfaction	0.3	0.4	0.4	-0.5	0.7
Mother’s age at death	0.3	0.4	0.8	-0.9	-0.3
Medication: Bendroflumethiazide	0.3	0.5	0.7	-0.4	-0.8
Fractured/broken bones in last 5 years	0.3	0.3	0.7	-0.2	0.8
Commuting to job workplace: Cycle	0.3	0.4	0.7	-0.3	-0.8
Reaction Time	0.2	0.4	0.6	0.5	0.8
Verbal and Numeric Reasoning (VNR)	0.2	0.5	0.8	-0.9	0.4
Blood White Count	0.2	1.3	2.6	1.6	0.1
Chronotype (morning person)	0.2	0.5	0.7	0.6	0.8
Vitamin and mineral supplements	0.2	0.2	0.4	-0.7	0.0
Medication: Co-codamol	0.2	0.2	0.4	0.0	0.6
Fluid intelligence score	0.2	0.4	0.6	-0.5	0.7
Impedance of arm (right)	0.2	1.0	1.5	-0.7	-1.2
Impedance of arm (left)	0.2	0.9	1.1	-1.1	-0.8
Loud music exposure frequency	0.2	0.2	0.3	0.3	0.5
Blood clot in the leg (DVT)	0.2	0.3	0.5	0.7	-0.2
Headache pain in last month	0.2	0.4	0.8	0.9	-0.2
Gout (self-reported)	0.2	0.3	0.4	-0.4	-0.6
Medication: Ventolin 100micrograms inhaler	0.2	0.2	0.3	-0.4	-0.6
Emphysema/chronic bronchitis	0.2	0.2	0.3	0.1	0.6
Heart disease (mother)	0.2	0.2	0.3	-0.5	0.3
Chest pain or discomfort	0.2	0.3	0.3	0.6	-0.6
Loneliness, isolation	0.2	0.3	0.3	0.6	0.5
Osteoporosis (self-reported)	0.2	0.2	0.4	0.2	0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.4	0.6	0.8	0.4
Alcohol drinker status: Never	0.2	0.2	0.5	0.7	0.0
Myopia	0.2	0.3	0.3	0.4	0.6
Basal cell carcinoma (self-reported)	0.2	0.2	0.4	0.7	0.1
Irritable Bowel Disease (IBD)	0.1	0.2	0.4	-0.2	-0.6
Fasting Glucose	0.1	0.1	0.1	-0.2	-0.3
HDL Cholesterol	0.1	0.2	0.4	0.6	-0.3
LDL Cholesterol	0.1	0.1	0.2	-0.4	0.1
Triglycerides	0.1	0.1	0.2	0.1	-0.5
Blood Red Count	0.1	1.1	2.2	-0.0	-1.5
Allergy or Eczema	0.1	0.2	0.2	-0.5	-0.4
Respiratory disease	0.1	0.1	0.2	0.5	-0.0
Tanning	0.1	1.1	1.6	1.3	0.7
Ever had hysterectomy (womb removed)	0.1	0.1	0.2	0.4	-0.4
Angina	0.1	0.2	0.3	0.5	0.4
Diabetes (mother)	0.1	0.2	0.3	0.6	0.1
Relative age voice broke	0.1	0.1	0.3	0.2	-0.5
Multivitamins +/- minerals	0.1	0.1	0.2	-0.1	0.4
Medication: Atenolol	0.1	0.1	0.1	-0.3	-0.3
High blood pressure (mother)	0.1	0.1	0.2	-0.4	0.1
Ever unenthusiastic/disinterested for a whole week	0.1	0.1	0.1	-0.1	0.4
Qualifications: None of the above	0.1	0.2	0.4	-0.0	0.6
Allergy	0.1	0.2	0.2	0.4	0.4
Time employed in main current job	0.1	0.1	0.3	-0.1	0.5
Father’s age at death	0.1	0.1	0.2	0.5	0.2
Pulse wave Arterial Stiffness index	0.1	0.1	0.1	0.3	-0.2
Shortness of breath walking on level ground	0.1	0.1	0.2	-0.4	-0.2
Angina (self-reported)	0.1	0.1	0.1	0.3	0.3
Migraine (self-reported)	0.1	0.1	0.1	-0.3	0.2
Mean time to correctly identify matches	0.1	0.2	0.3	0.5	-0.3
Number of full sisters	0.1	0.1	0.1	-0.1	-0.4
Handedness (chirality/laterality): Left-handed	0.1	0.2	0.2	0.4	0.4
Back pain experienced in last month	0.1	0.1	0.1	-0.3	0.3
Asthma (self-reported)	0.1	0.2	0.4	0.6	-0.2
Wears glasses or contact lenses	0.1	0.1	0.3	0.5	0.1
Pain type(s) experienced in last month: Hip pain	0.1	0.2	0.2	0.5	0.3
Crohns Disease (2017)	0.0	0.0	0.0	0.1	-0.0
Blood Eosinophil Count	0.0	0.3	0.3	0.4	-0.6
Blood Platelet Count	0.0	0.1	0.2	-0.4	0.1
Hair Pigment	0.0	0.1	0.1	0.1	0.3
Number of treatments/medications taken	0.0	0.1	0.1	0.3	-0.0
Average weekly spirits intake	0.0	0.0	0.1	-0.0	-0.3
Tinnitus: Yes, but not now, but have in the past	0.0	0.0	0.0	0.1	0.1
Alcohol usually taken with meals	0.0	0.0	0.0	0.0	0.1
Qualifications: A levels/AS levels or equivalent	0.0	0.0	0.1	-0.0	-0.3
Asthma	0.0	0.0	0.0	0.2	0.0
Medication: Lansoprazole	0.0	0.0	0.0	-0.1	-0.1
Hypothyroidism/myxoedema (self-reported)	0.0	0.0	0.0	0.2	0.1
Leg fat percentage (right)	0.0	0.0	0.1	0.2	-0.2
Wheeze or whistling in the chest in last year	0.0	0.1	0.1	-0.2	0.2
Illnesses of father: Heart disease	0.0	0.1	0.1	0.2	-0.3
Osteoarthritis (self-reported)	0.0	0.1	0.1	0.2	-0.3
Leg fat percentage (left)	0.0	0.1	0.2	0.5	-0.1
Deep venous thrombosis (DVT) (self-reported)	0.0	0.1	0.1	0.3	0.0

Hub : Genes

HMCES

Models

Trait associations